STRINGSTRING
RK21_04129 RK21_04129 GCA_000688275_00268 GCA_000688275_00268 CMV24_29695 CMV24_29695 CMV24_16990 CMV24_16990 nfuA nfuA RK21_03069 RK21_03069 CMV24_10690 CMV24_10690 ilvD ilvD CMV24_00065 CMV24_00065 CMV24_00185 CMV24_00185 CMV24_00315 CMV24_00315 CMV24_00320 CMV24_00320 RK21_05474 RK21_05474 sdhB sdhB RK21_00894 RK21_00894 CMV24_07350 CMV24_07350 RK21_00848 RK21_00848 hemN hemN xdhA xdhA CMV24_05840 CMV24_05840 C7318_1616 C7318_1616 RK21_03984 RK21_03984 RK21_00352 RK21_00352 grxD grxD RK21_00355 RK21_00355 nth nth CMV24_21765 CMV24_21765 dinG dinG CMV24_26070 CMV24_26070 CMV24_24490 CMV24_24490 peaB peaB GCA_000688275_01625 GCA_000688275_01625 lipA lipA ispG ispG rlmN rlmN RK21_05186 RK21_05186 erpA erpA pqqE pqqE bioB bioB gbcB gbcB CMV24_11365 CMV24_11365 RK21_03318 RK21_03318 RK21_00147 RK21_00147 CMV24_12040 CMV24_12040 RK21_00230 RK21_00230 GCA_000688275_03179 GCA_000688275_03179 lipA-2 lipA-2 fdxH fdxH RK21_04525 RK21_04525 CMV24_20520 CMV24_20520 CMV24_02310 CMV24_02310 CMV24_02575 CMV24_02575 paaJ paaJ RK21_01983 RK21_01983 CMV24_24595 CMV24_24595 benA benA GCA_000688275_03707 GCA_000688275_03707 CMV24_25910 CMV24_25910 RK21_01662 RK21_01662 GCA_000688275_03812 GCA_000688275_03812 GCA_000688275_03814 GCA_000688275_03814 ccoG ccoG rlmD rlmD ttcA ttcA CMV24_09510 CMV24_09510 RK21_03694 RK21_03694 RK21_03696 RK21_03696 leuC leuC GCA_000688275_04267 GCA_000688275_04267 nuoB nuoB CMV24_15920 CMV24_15920 CMV24_15915 CMV24_15915 RK21_00978 RK21_00978 nuoI nuoI RK21_03470 RK21_03470 ispH ispH GCA_000688275_04669 GCA_000688275_04669 CMV24_10205 CMV24_10205 CMV24_16305 CMV24_16305 CMV24_16300 CMV24_16300 GCA_000688275_00140 GCA_000688275_00140 GCA_000688275_00187 GCA_000688275_00187 CMV24_17325 CMV24_17325 edd edd CMV24_09960 CMV24_09960 rimO rimO queE queE nadA nadA moaA moaA CMV24_23305 CMV24_23305 fdx fdx CMV24_03805 CMV24_03805 C7318_1492 C7318_1492 iscS iscS CMV24_20040 CMV24_20040 CMV24_20045 CMV24_20045 CMV24_20050 CMV24_20050 CMV24_15415 CMV24_15415 RK21_03111 RK21_03111 prpD prpD acnB acnB GCA_000688275_02297 GCA_000688275_02297 GCA_000688275_00265 GCA_000688275_00265 RK21_04771 RK21_04771 CMV24_11215 CMV24_11215 CMV24_11270 CMV24_11270 CMV24_11345 CMV24_11345 RK21_05706 RK21_05706 CMV24_01375 CMV24_01375 queG queG thiC thiC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RK21_04129Unannotated protein. (127 aa)
GCA_000688275_00268Unannotated protein. (424 aa)
CMV24_29695Unannotated protein. (172 aa)
CMV24_16990Unannotated protein. (411 aa)
nfuAUnannotated protein; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. (194 aa)
RK21_03069Unannotated protein. (550 aa)
CMV24_10690Unannotated protein. (322 aa)
ilvDUnannotated protein; Belongs to the IlvD/Edd family. (613 aa)
CMV24_00065Unannotated protein. (83 aa)
CMV24_00185Unannotated protein; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. (391 aa)
CMV24_00315Unannotated protein. (1481 aa)
CMV24_00320Unannotated protein. (472 aa)
RK21_05474Unannotated protein. (134 aa)
sdhBUnannotated protein. (234 aa)
RK21_00894Unannotated protein; Accepts electrons from ETF and reduces ubiquinone. (554 aa)
CMV24_07350Unannotated protein. (178 aa)
RK21_00848Unannotated protein. (471 aa)
hemNUnannotated protein; Belongs to the anaerobic coproporphyrinogen-III oxidase family. (460 aa)
xdhAUnannotated protein. (484 aa)
CMV24_05840Unannotated protein. (1006 aa)
C7318_1616Unannotated protein; Belongs to the BolA/IbaG family. (79 aa)
RK21_03984Unannotated protein; Belongs to the iron-sulfur dependent L-serine dehydratase family. (458 aa)
RK21_00352Unannotated protein; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (705 aa)
grxDUnannotated protein; Belongs to the glutaredoxin family. Monothiol subfamily. (111 aa)
RK21_00355Unannotated protein. (73 aa)
nthUnannotated protein; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (212 aa)
CMV24_21765Unannotated protein; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. (364 aa)
dinGUnannotated protein; DNA-dependent ATPase and 5'-3' DNA helicase. (714 aa)
CMV24_26070Unannotated protein. (151 aa)
CMV24_24490Unannotated protein; Belongs to the iron-sulfur dependent L-serine dehydratase family. (458 aa)
peaBUnannotated protein. (476 aa)
GCA_000688275_01625Unannotated protein. (252 aa)
lipAUnannotated protein; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (332 aa)
ispGUnannotated protein; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (369 aa)
rlmNUnannotated protein; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family. (381 aa)
RK21_05186Unannotated protein. (351 aa)
erpAUnannotated protein; Required for insertion of 4Fe-4S clusters for at least IspG. (116 aa)
pqqEUnannotated protein; Catalyzes the cross-linking of a glutamate residue and a tyrosine residue in the PqqA protein as part of the biosynthesis of pyrroloquinoline quinone (PQQ). (382 aa)
bioBUnannotated protein; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (352 aa)
gbcBUnannotated protein. (366 aa)
CMV24_11365Unannotated protein. (430 aa)
RK21_03318Unannotated protein; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (913 aa)
RK21_00147Unannotated protein; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. (197 aa)
CMV24_12040Unannotated protein; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (507 aa)
RK21_00230Unannotated protein. (306 aa)
GCA_000688275_03179Unannotated protein. (237 aa)
lipA-2Unannotated protein; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (338 aa)
fdxHUnannotated protein; The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers. (316 aa)
RK21_04525Unannotated protein; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (809 aa)
CMV24_20520Unannotated protein. (196 aa)
CMV24_02310Unannotated protein. (936 aa)
CMV24_02575Unannotated protein. (105 aa)
paaJUnannotated protein. (177 aa)
RK21_01983Unannotated protein. (358 aa)
CMV24_24595Unannotated protein. (336 aa)
benAUnannotated protein. (452 aa)
GCA_000688275_03707Unannotated protein. (156 aa)
CMV24_25910Unannotated protein. (406 aa)
RK21_01662Unannotated protein. (284 aa)
GCA_000688275_03812Unannotated protein. (577 aa)
GCA_000688275_03814Unannotated protein. (389 aa)
ccoGUnannotated protein. (466 aa)
rlmDUnannotated protein; Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily. (452 aa)
ttcAUnannotated protein; Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system. (274 aa)
CMV24_09510Unannotated protein. (122 aa)
RK21_03694Unannotated protein. (120 aa)
RK21_03696Unannotated protein; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. (641 aa)
leuCUnannotated protein; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (477 aa)
GCA_000688275_04267Unannotated protein. (335 aa)
nuoBUnannotated protein; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (225 aa)
CMV24_15920Unannotated protein. (165 aa)
CMV24_15915Unannotated protein; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Belongs to the complex I 51 kDa subunit family. (454 aa)
RK21_00978Unannotated protein; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. Belongs to the complex I 75 kDa subunit family. (904 aa)
nuoIUnannotated protein; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (182 aa)
RK21_03470Unannotated protein; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (322 aa)
ispHUnannotated protein; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (315 aa)
GCA_000688275_04669Unannotated protein. (614 aa)
CMV24_10205Unannotated protein. (117 aa)
CMV24_16305Unannotated protein. (455 aa)
CMV24_16300Unannotated protein. (424 aa)
GCA_000688275_00140Unannotated protein. (108 aa)
GCA_000688275_00187Unannotated protein. (832 aa)
CMV24_17325Unannotated protein. (384 aa)
eddUnannotated protein; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. (608 aa)
CMV24_09960Unannotated protein; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. (107 aa)
rimOUnannotated protein; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily. (443 aa)
queEUnannotated protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. (215 aa)
nadAUnannotated protein; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate; Belongs to the quinolinate synthase A family. Type 1 subfamily. (352 aa)
moaAUnannotated protein; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (334 aa)
CMV24_23305Unannotated protein; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (776 aa)
fdxUnannotated protein. (113 aa)
CMV24_03805Unannotated protein; Is able to transfer iron-sulfur clusters to apo-ferredoxin. Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system; Belongs to the HesB/IscA family. (107 aa)
C7318_1492Unannotated protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. (128 aa)
iscSUnannotated protein; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. (404 aa)
CMV24_20040Unannotated protein. (160 aa)
CMV24_20045Unannotated protein. (519 aa)
CMV24_20050Unannotated protein. (956 aa)
CMV24_15415Unannotated protein; Reduction of activated sulfate into sulfite. (244 aa)
RK21_03111Unannotated protein. (885 aa)
prpDUnannotated protein. (494 aa)
acnBUnannotated protein; Belongs to the aconitase/IPM isomerase family. (697 aa)
GCA_000688275_02297Unannotated protein. (81 aa)
GCA_000688275_00265Unannotated protein. (319 aa)
RK21_04771Unannotated protein; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (781 aa)
CMV24_11215Unannotated protein; Adenine glycosylase active on G-A mispairs. (355 aa)
CMV24_11270Unannotated protein; Belongs to the iron-sulfur dependent L-serine dehydratase family. (458 aa)
CMV24_11345Unannotated protein. (650 aa)
RK21_05706Unannotated protein. (438 aa)
CMV24_01375Unannotated protein. (766 aa)
queGUnannotated protein; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr); Belongs to the QueG family. (354 aa)
thiCUnannotated protein; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. (628 aa)
Your Current Organism:
Pseudomonas plecoglossicida
NCBI taxonomy Id: 1215115
Other names: P. plecoglossicida NBRC 103162 = DSM 15088, Pseudomonas plecoglossicida DSM 15088, Pseudomonas plecoglossicida DSM 15088 = NBRC 103162, Pseudomonas plecoglossicida NBRC 103162, Pseudomonas plecoglossicida NBRC 103162 = DSM 15088
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