STRINGSTRING
glk glk ctaD ctaD gyrB gyrB rpmH rpmH cyaY cyaY rpsF rpsF CMV24_21985 CMV24_21985 bfr bfr iscX iscX fdx fdx hscA hscA hscB hscB cyoD cyoD rplY rplY recA recA pyrH pyrH rpsB rpsB rplS rplS rpsU rpsU RK21_03962 RK21_03962 hutU hutU rho rho fusA-2 fusA-2 infA infA rpsT rpsT rpmF rpmF fusA fusA C7318_1586 C7318_1586 pgi pgi greA greA C7318_0526 C7318_0526 rplF rplF bfr-2 bfr-2 nrdR nrdR nusB nusB infC infC ftsZ ftsZ rpsI rpsI rplM rplM topA topA RK21_03277 RK21_03277 efp efp ccmA ccmA ccoP-2 ccoP-2 ccoN-2 ccoN-2 ccoP ccoP ccoN ccoN sdhD sdhD sdhB sdhB hutG hutG hutH-2 hutH-2 hutH hutH
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
glkUnannotated protein; Belongs to the bacterial glucokinase family. (319 aa)
ctaDUnannotated protein; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B. (529 aa)
gyrBUnannotated protein; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (806 aa)
rpmHUnannotated protein; Belongs to the bacterial ribosomal protein bL34 family. (44 aa)
cyaYUnannotated protein; Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis. (110 aa)
rpsFUnannotated protein; Binds together with S18 to 16S ribosomal RNA. (141 aa)
CMV24_21985Unannotated protein. (251 aa)
bfrUnannotated protein; Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex; Belongs to the bacterioferritin family. (157 aa)
iscXUnannotated protein. (66 aa)
fdxUnannotated protein. (113 aa)
hscAUnannotated protein; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. (620 aa)
hscBUnannotated protein; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family. (173 aa)
cyoDUnannotated protein. (110 aa)
rplYUnannotated protein; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily. (198 aa)
recAUnannotated protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. (355 aa)
pyrHUnannotated protein; Catalyzes the reversible phosphorylation of UMP to UDP. (247 aa)
rpsBUnannotated protein; Belongs to the universal ribosomal protein uS2 family. (245 aa)
rplSUnannotated protein; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. (116 aa)
rpsUUnannotated protein; Belongs to the bacterial ribosomal protein bS21 family. (71 aa)
RK21_03962Unannotated protein; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (333 aa)
hutUUnannotated protein; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate. (559 aa)
rhoUnannotated protein; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. (419 aa)
fusA-2Unannotated protein; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. (715 aa)
infAUnannotated protein; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. (72 aa)
rpsTUnannotated protein; Binds directly to 16S ribosomal RNA. (92 aa)
rpmFUnannotated protein; Belongs to the bacterial ribosomal protein bL32 family. (60 aa)
fusAUnannotated protein; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. (703 aa)
C7318_1586Unannotated protein. (345 aa)
pgiUnannotated protein; Belongs to the GPI family. (554 aa)
greAUnannotated protein; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides. (160 aa)
C7318_0526Unannotated protein. (55 aa)
rplFUnannotated protein; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. (177 aa)
bfr-2Unannotated protein; Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex; Belongs to the bacterioferritin family. (154 aa)
nrdRUnannotated protein; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. (154 aa)
nusBUnannotated protein; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. (166 aa)
infCUnannotated protein; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins. (183 aa)
ftsZUnannotated protein; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. (398 aa)
rpsIUnannotated protein; Belongs to the universal ribosomal protein uS9 family. (130 aa)
rplMUnannotated protein; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. (142 aa)
topAUnannotated protein; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] (870 aa)
RK21_03277Unannotated protein; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (487 aa)
efpUnannotated protein; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. (191 aa)
ccmAUnannotated protein; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family. (210 aa)
ccoP-2Unannotated protein; C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex. (325 aa)
ccoN-2Unannotated protein; Belongs to the heme-copper respiratory oxidase family. (480 aa)
ccoPUnannotated protein; C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex. (311 aa)
ccoNUnannotated protein; Belongs to the heme-copper respiratory oxidase family. (474 aa)
sdhDUnannotated protein; Membrane-anchoring subunit of succinate dehydrogenase (SDH). (122 aa)
sdhBUnannotated protein. (234 aa)
hutGUnannotated protein. (267 aa)
hutH-2Unannotated protein. (510 aa)
hutHUnannotated protein. (507 aa)
Your Current Organism:
Pseudomonas plecoglossicida
NCBI taxonomy Id: 1215115
Other names: P. plecoglossicida NBRC 103162 = DSM 15088, Pseudomonas plecoglossicida DSM 15088, Pseudomonas plecoglossicida DSM 15088 = NBRC 103162, Pseudomonas plecoglossicida NBRC 103162, Pseudomonas plecoglossicida NBRC 103162 = DSM 15088
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