STRINGSTRING
ENX15535.1 ENX15535.1 ppc ppc ENX18086.1 ENX18086.1 ENX18087.1 ENX18087.1 acsA acsA ENX18166.1 ENX18166.1 leuA leuA ENX17997.1 ENX17997.1 ENX18001.1 ENX18001.1 ackA ackA ENX17806.1 ENX17806.1 ENX17543.1 ENX17543.1 ENX17692.1 ENX17692.1 mqo mqo accA accA mdh mdh ENX17176.1 ENX17176.1 ENX17250.1 ENX17250.1 ENX16251.1 ENX16251.1 ENX16288.1 ENX16288.1 dld dld lldD lldD ENX16049.1 ENX16049.1 ENX16141.1 ENX16141.1 ENX15287.1 ENX15287.1 ENX15294.1 ENX15294.1 ENX15295.1 ENX15295.1 fumC fumC ENX15499.1 ENX15499.1 ENX15501.1 ENX15501.1 ENX15565.1 ENX15565.1 glcB glcB ENX15765.1 ENX15765.1 ENX14430.1 ENX14430.1 ENX13179.1 ENX13179.1 ENX13206.1 ENX13206.1 gloB gloB ENX13267.1 ENX13267.1 ENX12492.1 ENX12492.1 ENX12500.1 ENX12500.1 ENX12551.1 ENX12551.1 ENX12587.1 ENX12587.1 ENX12282.1 ENX12282.1 pckG pckG ENX11856.1 ENX11856.1 ENX11942.1 ENX11942.1 ENX12038.1 ENX12038.1 ENX12039.1 ENX12039.1 ENX12049.1 ENX12049.1 accD accD ENX11234.1 ENX11234.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENX15535.1Chaperone hchA. (291 aa)
ppcPhosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (893 aa)
ENX18086.1Pyruvate dehydrogenase (acetyl-transferring), homodimeric type; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (905 aa)
ENX18087.1Dihydrolipoyllysine-residue acetyltransferase. (656 aa)
acsAacetate-CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (647 aa)
ENX18166.1Hypothetical protein. (504 aa)
leuA2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. (565 aa)
ENX17997.1Hypothetical protein; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (508 aa)
ENX18001.1Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. (708 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (391 aa)
ENX17806.1NAD-dependent malic enzyme. (566 aa)
ENX17543.1Hypothetical protein. (125 aa)
ENX17692.1Hypothetical protein. (325 aa)
mqoMalate dehydrogenase (acceptor). (546 aa)
accAAcetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (274 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. (328 aa)
ENX17176.1Hypothetical protein; Belongs to the aldehyde dehydrogenase family. (484 aa)
ENX17250.1Hypothetical protein. (214 aa)
ENX16251.1Hypothetical protein. (306 aa)
ENX16288.1Hypothetical protein. (549 aa)
dldHypothetical protein; Catalyzes the oxidation of D-lactate to pyruvate. Belongs to the quinone-dependent D-lactate dehydrogenase family. (568 aa)
lldDL-lactate dehydrogenase [cytochrome]; Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain; Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family. (381 aa)
ENX16049.1Hypothetical protein; Belongs to the thiolase-like superfamily. Thiolase family. (511 aa)
ENX16141.1Hypothetical protein. (186 aa)
ENX15287.1Hypothetical protein. (182 aa)
ENX15294.1acetyl-CoA carboxylase, biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (454 aa)
ENX15295.1acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (141 aa)
fumCFumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (464 aa)
ENX15499.1Hypothetical protein. (230 aa)
ENX15501.1Hypothetical protein. (266 aa)
ENX15565.1Hypothetical protein. (290 aa)
glcBMalate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. (720 aa)
ENX15765.1Hypothetical protein. (146 aa)
ENX14430.1Hypothetical protein. (313 aa)
ENX13179.1Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (503 aa)
ENX13206.1Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (792 aa)
gloBHydroxyacylglutathione hydrolase; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid. (243 aa)
ENX13267.1Hypothetical protein. (756 aa)
ENX12492.1Hypothetical protein. (100 aa)
ENX12500.1Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. (133 aa)
ENX12551.1Hypothetical protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (321 aa)
ENX12587.1Hypothetical protein. (573 aa)
ENX12282.1Hypothetical protein. (64 aa)
pckGPhosphoenolpyruvate carboxykinase [GTP]; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. (609 aa)
ENX11856.1Dihydrolipoyl dehydrogenase. (477 aa)
ENX11942.1Hypothetical protein; Belongs to the aldehyde dehydrogenase family. (486 aa)
ENX12038.1Hypothetical protein; Belongs to the thiolase-like superfamily. Thiolase family. (391 aa)
ENX12039.1Hypothetical protein. (147 aa)
ENX12049.1Hypothetical protein; Belongs to the thiolase-like superfamily. Thiolase family. (401 aa)
accDAcetyl-coenzyme A carboxylase carboxyl transferase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (298 aa)
ENX11234.1Hypothetical protein. (284 aa)
Your Current Organism:
Acinetobacter sp. CIP64.2
NCBI taxonomy Id: 1217694
Other names: A. sp. CIP 64.2, Acinetobacter sp. CIP 64.2
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