STRINGSTRING
hisG hisG hisE hisE suhB_2 suhB_2 hprA_1 hprA_1 hisI hisI hisF hisF suhB_1 suhB_1 hisA hisA GCA_001895045_01000 GCA_001895045_01000 hisH hisH GCA_001895045_01002 GCA_001895045_01002 hisB hisB hisC hisC hisD hisD serA serA serB_3 serB_3 hisN hisN ino1 ino1 serC serC gpmA gpmA serB_2 serB_2 GCA_001895045_03874 GCA_001895045_03874 serB_1 serB_1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
hisGUnannotated protein; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily. (287 aa)
hisEUnannotated protein. (93 aa)
suhB_2Unannotated protein; Belongs to the inositol monophosphatase superfamily. (292 aa)
hprA_1Unannotated protein. (311 aa)
hisIUnannotated protein; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. (119 aa)
hisFUnannotated protein; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (257 aa)
suhB_1Unannotated protein. (274 aa)
hisAUnannotated protein. (244 aa)
GCA_001895045_01000Unannotated protein. (81 aa)
hisHUnannotated protein; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (211 aa)
GCA_001895045_01002Unannotated protein. (405 aa)
hisBUnannotated protein. (204 aa)
hisCUnannotated protein; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (377 aa)
hisDUnannotated protein; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (440 aa)
serAUnannotated protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (530 aa)
serB_3Unannotated protein. (410 aa)
hisNUnannotated protein. (262 aa)
ino1Unannotated protein. (366 aa)
serCUnannotated protein; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (373 aa)
gpmAUnannotated protein; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (249 aa)
serB_2Unannotated protein. (328 aa)
GCA_001895045_03874Unannotated protein. (96 aa)
serB_1Unannotated protein. (288 aa)
Your Current Organism:
Rhodococcus coprophilus
NCBI taxonomy Id: 1219011
Other names: R. coprophilus NBRC 100603, Rhodococcus coprophilus NBRC 100603
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