STRINGSTRING
EYZ11_012703 EYZ11_012703 EYZ11_012598 EYZ11_012598 EYZ11_012106 EYZ11_012106 EYZ11_011659 EYZ11_011659 HTZ1 HTZ1 EYZ11_010624 EYZ11_010624 EYZ11_009808 EYZ11_009808 UFD1 UFD1 HTA1 HTA1 EYZ11_009720 EYZ11_009720 EYZ11_009653 EYZ11_009653 EYZ11_008786 EYZ11_008786 EYZ11_008789 EYZ11_008789 EYZ11_009661 EYZ11_009661 EYZ11_007453 EYZ11_007453 EYZ11_007179 EYZ11_007179 EYZ11_006956 EYZ11_006956 EYZ11_008643 EYZ11_008643 CSE4 CSE4 EYZ11_005461 EYZ11_005461 SUA7 SUA7 EYZ11_003551 EYZ11_003551 EYZ11_003375 EYZ11_003375 EYZ11_003099 EYZ11_003099 EYZ11_002744 EYZ11_002744 EYZ11_002646 EYZ11_002646 DOT1 DOT1 ORC2 ORC2 EYZ11_001876 EYZ11_001876 EYZ11_001853 EYZ11_001853 EYZ11_002473 EYZ11_002473 MCM7 MCM7 EYZ11_001851 EYZ11_001851 EYZ11_003001 EYZ11_003001 EYZ11_001189 EYZ11_001189 EYZ11_001064 EYZ11_001064 POL12 POL12 EYZ11_000840 EYZ11_000840 EYZ11_000546 EYZ11_000546 HHF1_1 HHF1_1 HHT1 HHT1 EYZ11_009583 EYZ11_009583 HTB1 HTB1 EYZ11_008256 EYZ11_008256 EYZ11_003703 EYZ11_003703 NPL4 NPL4 EYZ11_001124 EYZ11_001124 EYZ11_000549 EYZ11_000549 EYZ11_012912 EYZ11_012912
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
EYZ11_012703Uncharacterized protein. (410 aa)
EYZ11_012598ENDO3c domain-containing protein. (373 aa)
EYZ11_012106Telo_bind domain-containing protein. (582 aa)
EYZ11_011659Uncharacterized protein. (723 aa)
HTZ1Histone H2A; Belongs to the histone H2A family. (138 aa)
EYZ11_010624DNA primase; Belongs to the eukaryotic-type primase small subunit family. (508 aa)
EYZ11_009808DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family. (500 aa)
UFD1Ubiquitin fusion degradation protein. (450 aa)
HTA1Histone H2A; Belongs to the histone H2A family. (134 aa)
EYZ11_009720Uncharacterized protein. (408 aa)
EYZ11_009653Sld5 domain-containing protein. (209 aa)
EYZ11_008786Cnn_1N domain-containing protein. (871 aa)
EYZ11_008789Sld5 domain-containing protein. (183 aa)
EYZ11_009661DUF2236 domain-containing protein. (467 aa)
EYZ11_007453ORC_WH_C domain-containing protein. (666 aa)
EYZ11_007179H15 domain-containing protein. (173 aa)
EYZ11_006956AAA_16 domain-containing protein. (523 aa)
EYZ11_008643Uncharacterized protein. (858 aa)
CSE4Centromeric DNA-binding histone H3-like protein cse4. (179 aa)
EYZ11_005461Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (111 aa)
SUA7Transcription initiation factor IIB. (350 aa)
EYZ11_003551DNA polymerase. (1440 aa)
EYZ11_003375DNA helicase; Belongs to the MCM family. (951 aa)
EYZ11_003099Uncharacterized protein. (143 aa)
EYZ11_002744AAA domain-containing protein. (729 aa)
EYZ11_002646Uncharacterized protein; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (109 aa)
DOT1Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones. (500 aa)
ORC2Origin recognition complex subunit 2. (559 aa)
EYZ11_001876Uncharacterized protein. (76 aa)
EYZ11_001853Uncharacterized protein. (136 aa)
EYZ11_002473CENP-T_C domain-containing protein. (460 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (810 aa)
EYZ11_001851Uncharacterized protein. (258 aa)
EYZ11_003001DNA helicase; Belongs to the MCM family. (847 aa)
EYZ11_001189Cell division control protein; Belongs to the CDC6/cdc18 family. (525 aa)
EYZ11_001064DNA helicase; Belongs to the MCM family. (693 aa)
POL12DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (659 aa)
EYZ11_000840DNA helicase; Belongs to the MCM family. (1028 aa)
EYZ11_000546Uncharacterized protein. (453 aa)
HHF1_1Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
HHT1Histone H3; Belongs to the histone H3 family. (136 aa)
EYZ11_009583SLD3 domain-containing protein. (898 aa)
HTB1Histone H2B; Belongs to the histone H2B family. (141 aa)
EYZ11_008256Uncharacterized protein. (781 aa)
EYZ11_003703Uncharacterized protein. (468 aa)
NPL4Nuclear protein localization protein 4. (649 aa)
EYZ11_001124DNA helicase; Belongs to the MCM family. (842 aa)
EYZ11_000549DNA polymerase. (1028 aa)
EYZ11_012912RPA_C domain-containing protein. (258 aa)
Your Current Organism:
Aspergillus tanneri
NCBI taxonomy Id: 1220188
Other names: A. tanneri, ATCC MYA-4905, Aspergillus tanneri Kwon-Chung, Sugui & S. W. Peterson 2012, NIH1004, NRRL 62425, NRRL 62426, NRRL 63426
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.