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W2RJI9_9EURO W2RJI9_9EURO W2RJP6_9EURO W2RJP6_9EURO W2RL13_9EURO W2RL13_9EURO W2RMC1_9EURO W2RMC1_9EURO W2RMS7_9EURO W2RMS7_9EURO W2RNP2_9EURO W2RNP2_9EURO W2RPX1_9EURO W2RPX1_9EURO W2RPX8_9EURO W2RPX8_9EURO W2RPZ6_9EURO W2RPZ6_9EURO W2RR85_9EURO W2RR85_9EURO W2RRA0_9EURO W2RRA0_9EURO W2RRI5_9EURO W2RRI5_9EURO W2RS04_9EURO W2RS04_9EURO W2RSM8_9EURO W2RSM8_9EURO W2RT58_9EURO W2RT58_9EURO W2RTT4_9EURO W2RTT4_9EURO W2RU05_9EURO W2RU05_9EURO W2RVF5_9EURO W2RVF5_9EURO W2RVR1_9EURO W2RVR1_9EURO W2RVZ4_9EURO W2RVZ4_9EURO W2RWM0_9EURO W2RWM0_9EURO W2RY21_9EURO W2RY21_9EURO W2RY48_9EURO W2RY48_9EURO W2RYF1_9EURO W2RYF1_9EURO W2RYF8_9EURO W2RYF8_9EURO W2RZB8_9EURO W2RZB8_9EURO W2RZV5_9EURO W2RZV5_9EURO W2S0E0_9EURO W2S0E0_9EURO W2S1N0_9EURO W2S1N0_9EURO W2S1N4_9EURO W2S1N4_9EURO W2S1P6_9EURO W2S1P6_9EURO W2S1W4_9EURO W2S1W4_9EURO W2S264_9EURO W2S264_9EURO W2S2D8_9EURO W2S2D8_9EURO W2S2H2_9EURO W2S2H2_9EURO W2S2L1_9EURO W2S2L1_9EURO W2S325_9EURO W2S325_9EURO W2S477_9EURO W2S477_9EURO W2S4D5_9EURO W2S4D5_9EURO W2S4I3_9EURO W2S4I3_9EURO ADK2 ADK2 W2S541_9EURO W2S541_9EURO W2S5L3_9EURO W2S5L3_9EURO W2S6E5_9EURO W2S6E5_9EURO ADK1 ADK1 W2S6N0_9EURO W2S6N0_9EURO W2S7M4_9EURO W2S7M4_9EURO W2S7Z9_9EURO W2S7Z9_9EURO W2S8C3_9EURO W2S8C3_9EURO W2S925_9EURO W2S925_9EURO W2S978_9EURO W2S978_9EURO W2SA89_9EURO W2SA89_9EURO W2SAA3_9EURO W2SAA3_9EURO W2SAQ7_9EURO W2SAQ7_9EURO W2SB20_9EURO W2SB20_9EURO W2SB84_9EURO W2SB84_9EURO W2SBR5_9EURO W2SBR5_9EURO W2SBT5_9EURO W2SBT5_9EURO W2SC11_9EURO W2SC11_9EURO W2SD43_9EURO W2SD43_9EURO W2SDT4_9EURO W2SDT4_9EURO
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
experimentally determined
Predicted Interactions
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gene co-occurrence
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W2RJI9_9EUROQueuine tRNA-ribosyltransferase accessory subunit 2; Non-catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine); Belongs to the queuine tRNA-ribosyltransferase family. QTRT2 subfamily. (494 aa)
W2RJP6_9EUROThymidylate kinase. (221 aa)
W2RL13_9EUROFlavoprotein domain-containing protein. (232 aa)
W2RMC1_9EUROCytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (159 aa)
W2RMS7_9EUROUncharacterized protein. (379 aa)
W2RNP2_9EUROUncharacterized protein. (736 aa)
W2RPX1_9EUROUncharacterized protein. (252 aa)
W2RPX8_9EUROIMP-specific 5'-nucleotidase 1; IMP-specific 5'-nucleotidase involved in IMP (inositol monophosphate) degradation. (476 aa)
W2RPZ6_9EUROMetallophos domain-containing protein. (451 aa)
W2RR85_9EUROAB hydrolase-1 domain-containing protein. (332 aa)
W2RRA0_9EUROUncharacterized protein. (664 aa)
W2RRI5_9EUROUridylate kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and dUMP as phosphate acceptors, but can also use CMP, dCMP and AMP. Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. (227 aa)
W2RS04_9EUROAB hydrolase-1 domain-containing protein. (269 aa)
W2RSM8_9EUROS-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. (314 aa)
W2RT58_9EUROCMP/dCMP-type deaminase domain-containing protein. (379 aa)
W2RTT4_9EUROAB hydrolase-1 domain-containing protein. (345 aa)
W2RU05_9EUROCTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. (607 aa)
W2RVF5_9EUROInosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (201 aa)
W2RVR1_9EURODHFR domain-containing protein; Belongs to the dihydrofolate reductase family. (327 aa)
W2RVZ4_9EUROAdenylate kinase isoenzyme 6 homolog; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has also ATPase activity. May be involved in rRNA maturation and transcription regulation. (195 aa)
W2RWM0_9EURO4-nitrophenylphosphatase. (308 aa)
W2RY21_9EUROPfkB domain-containing protein. (405 aa)
W2RY48_9EUROUncharacterized protein; Belongs to the 5'-nucleotidase family. (598 aa)
W2RYF1_9EUROAdenosine deaminase. (419 aa)
W2RYF8_9EUROUncharacterized protein; Belongs to the 5'-nucleotidase family. (649 aa)
W2RZB8_9EUROAB hydrolase-1 domain-containing protein. (317 aa)
W2RZV5_9EUROGuanylate kinase. (208 aa)
W2S0E0_9EUROAdenosine deaminase. (383 aa)
W2S1N0_9EURORibD_C domain-containing protein. (193 aa)
W2S1N4_9EUROQueuine tRNA-ribosyltransferase catalytic subunit 1; Catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, formi [...] (406 aa)
W2S1P6_9EUROPyrimidine 5'-nucleotidase. (233 aa)
W2S1W4_9EUROPhosphonoacetate hydrolase. (420 aa)
W2S264_9EUROMetallophos domain-containing protein. (619 aa)
W2S2D8_9EUROInosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. (548 aa)
W2S2H2_9EUROAB hydrolase-1 domain-containing protein. (297 aa)
W2S2L1_9EUROUncharacterized protein; Belongs to the GDA1/CD39 NTPase family. (702 aa)
W2S325_9EUROThymidylate synthase. (388 aa)
W2S477_9EURODeoxyuridine 5'-triphosphate nucleotidohydrolase. (159 aa)
W2S4D5_9EUROHD domain-containing protein. (279 aa)
W2S4I3_9EUROIU_nuc_hydro domain-containing protein. (432 aa)
ADK2GTP:AMP phosphotransferase, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. (259 aa)
W2S541_9EURORibonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (899 aa)
W2S5L3_9EUROTIGR01456 family HAD hydrolase. (449 aa)
W2S6E5_9EUROUncharacterized protein. (440 aa)
ADK1Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. (276 aa)
W2S6N0_9EUROA_deaminase domain-containing protein. (591 aa)
W2S7M4_9EUROUncharacterized protein. (390 aa)
W2S7Z9_9EURORibonucleoside-diphosphate reductase small chain. (421 aa)
W2S8C3_9EUROUncharacterized protein. (669 aa)
W2S925_9EUROAB hydrolase-1 domain-containing protein. (276 aa)
W2S978_9EUROPribosyltran domain-containing protein. (206 aa)
W2SA89_9EUROUncharacterized protein; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (374 aa)
W2SAA3_9EUROGTP-binding protein YchF. (394 aa)
W2SAQ7_9EUROUncharacterized protein; Belongs to the GDA1/CD39 NTPase family. (563 aa)
W2SB20_9EUROGMP synthase [glutamine-hydrolyzing]. (545 aa)
W2SB84_9EUROAdenine phosphoribosyltransferase. (214 aa)
W2SBR5_9EUROAB hydrolase-1 domain-containing protein. (348 aa)
W2SBT5_9EUROUncharacterized protein. (287 aa)
W2SC11_9EURONudix hydrolase domain-containing protein. (376 aa)
W2SD43_9EUROGRIP domain-containing protein. (541 aa)
W2SDT4_9EUROA_deaminase domain-containing protein. (619 aa)
Your Current Organism:
Cyphellophora europaea
NCBI taxonomy Id: 1220924
Other names: C. europaea CBS 101466, Cyphellophora europaea CBS 101466, Phialophora europaea CBS 101466
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