(45 nodes) Ubiquitin-dependent ERAD pathway network (Cyphellophora europaea)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	W2RYT7_9EURO	UBIQUITIN_CONJUGAT_2 domain-containing protein. (382 aa)
	W2RX55_9EURO	ANK_REP_REGION domain-containing protein. (646 aa)
	W2RWZ7_9EURO	Protein transporter SEC61 subunit alpha; Belongs to the SecY/SEC61-alpha family. (476 aa)
	W2RWY2_9EURO	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (244 aa)
	W2RWW5_9EURO	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family. (257 aa)
	W2RWJ7_9EURO	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family. (258 aa)
	W2RWV2_9EURO	UV excision repair protein Rad23. (408 aa)
	W2RWA4_9EURO	WD_REPEATS_REGION domain-containing protein; Belongs to the WD repeat SEC13 family. (312 aa)
	W2RVL0_9EURO	Chaperone DnaK; Belongs to the heat shock protein 70 family. (673 aa)
	W2RVA4_9EURO	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (591 aa)
	W2RU24_9EURO	ATPase_AAA_core domain-containing protein. (538 aa)
	W2RT96_9EURO	Uncharacterized protein. (1833 aa)
	W2RSG0_9EURO	RING-CH-type domain-containing protein. (1634 aa)
	W2RR66_9EURO	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (779 aa)
	W2RQI9_9EURO	Uncharacterized protein. (329 aa)
	W2RPZ5_9EURO	26S protease regulatory subunit 10B; Belongs to the AAA ATPase family. (393 aa)
	W2RPN8_9EURO	UBX domain-containing protein. (517 aa)
	W2RPI6_9EURO	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (467 aa)
	W2RNF6_9EURO	Uncharacterized protein. (417 aa)
	W2RMC4_9EURO	HECT domain-containing protein. (1225 aa)
	W2RMC0_9EURO	ATPase_AAA_core domain-containing protein. (499 aa)
	W2RLB2_9EURO	RING-type domain-containing protein. (822 aa)
	W2RJ42_9EURO	Long chronological lifespan protein 2; Probable component of the endoplasmic reticulum-associated degradation (ERAD) pathway. (120 aa)
	W2SGW0_9EURO	J domain-containing protein. (350 aa)
	W2SF02_9EURO	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (884 aa)
	W2SER0_9EURO	U-box domain-containing protein. (1081 aa)
	W2SEJ9_9EURO	Uncharacterized protein. (366 aa)
	W2SEC3_9EURO	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (593 aa)
	W2SE67_9EURO	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (1070 aa)
	W2SDJ5_9EURO	Uncharacterized protein. (761 aa)
	W2SBW6_9EURO	TPR_REGION domain-containing protein. (335 aa)
	W2SBS8_9EURO	UBX domain-containing protein. (502 aa)
	W2SB24_9EURO	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (593 aa)
	W2S9D9_9EURO	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (166 aa)
	W2S8R0_9EURO	PRKCSH domain-containing protein. (465 aa)
	W2S7D8_9EURO	Uncharacterized protein. (348 aa)
	W2S6W2_9EURO	N-acetyltransferase domain-containing protein. (190 aa)
	W2S4U5_9EURO	Uncharacterized protein. (906 aa)
	W2S488_9EURO	Uncharacterized protein. (183 aa)
	W2S3V0_9EURO	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (566 aa)
	W2S3C9_9EURO	J domain-containing protein. (279 aa)
	W2S2G6_9EURO	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (623 aa)
	W2S253_9EURO	UBIQUITIN_CONJUGAT_2 domain-containing protein. (277 aa)
	W2S0B2_9EURO	UBX domain-containing protein. (544 aa)
	W2RZK4_9EURO	Cell division control protein 48; Belongs to the AAA ATPase family. (820 aa)

Your Current Organism:

Cyphellophora europaea

NCBI taxonomy Id: 1220924
Other names: C. europaea CBS 101466, Cyphellophora europaea CBS 101466, Phialophora europaea CBS 101466

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
W2RLB2_9EURO	W2RMC0_9EURO	W2RLB2	W2RMC0	RING-type domain-containing protein.	ATPase_AAA_core domain-containing protein.	0.938
W2RLB2_9EURO	W2RQI9_9EURO	W2RLB2	W2RQI9	RING-type domain-containing protein.	Uncharacterized protein.	0.406
W2RLB2_9EURO	W2RSG0_9EURO	W2RLB2	W2RSG0	RING-type domain-containing protein.	RING-CH-type domain-containing protein.	0.837
W2RLB2_9EURO	W2RU24_9EURO	W2RLB2	W2RU24	RING-type domain-containing protein.	ATPase_AAA_core domain-containing protein.	0.938
W2RLB2_9EURO	W2RVL0_9EURO	W2RLB2	W2RVL0	RING-type domain-containing protein.	Chaperone DnaK; Belongs to the heat shock protein 70 family.	0.751
W2RLB2_9EURO	W2RWJ7_9EURO	W2RLB2	W2RWJ7	RING-type domain-containing protein.	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	0.996
W2RLB2_9EURO	W2RWV2_9EURO	W2RLB2	W2RWV2	RING-type domain-containing protein.	UV excision repair protein Rad23.	0.800
W2RLB2_9EURO	W2RWW5_9EURO	W2RLB2	W2RWW5	RING-type domain-containing protein.	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	0.995
W2RLB2_9EURO	W2RWY2_9EURO	W2RLB2	W2RWY2	RING-type domain-containing protein.	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.590
W2RLB2_9EURO	W2RWZ7_9EURO	W2RLB2	W2RWZ7	RING-type domain-containing protein.	Protein transporter SEC61 subunit alpha; Belongs to the SecY/SEC61-alpha family.	0.809
W2RLB2_9EURO	W2RYT7_9EURO	W2RLB2	W2RYT7	RING-type domain-containing protein.	UBIQUITIN_CONJUGAT_2 domain-containing protein.	0.588
W2RLB2_9EURO	W2RZK4_9EURO	W2RLB2	W2RZK4	RING-type domain-containing protein.	Cell division control protein 48; Belongs to the AAA ATPase family.	0.938
W2RLB2_9EURO	W2S0B2_9EURO	W2RLB2	W2S0B2	RING-type domain-containing protein.	UBX domain-containing protein.	0.691
W2RLB2_9EURO	W2S253_9EURO	W2RLB2	W2S253	RING-type domain-containing protein.	UBIQUITIN_CONJUGAT_2 domain-containing protein.	0.523
W2RLB2_9EURO	W2S488_9EURO	W2RLB2	W2S488	RING-type domain-containing protein.	Uncharacterized protein.	0.971
W2RLB2_9EURO	W2S4U5_9EURO	W2RLB2	W2S4U5	RING-type domain-containing protein.	Uncharacterized protein.	0.996
W2RLB2_9EURO	W2S7D8_9EURO	W2RLB2	W2S7D8	RING-type domain-containing protein.	Uncharacterized protein.	0.736
W2RLB2_9EURO	W2S8R0_9EURO	W2RLB2	W2S8R0	RING-type domain-containing protein.	PRKCSH domain-containing protein.	0.971
W2RLB2_9EURO	W2S9D9_9EURO	W2RLB2	W2S9D9	RING-type domain-containing protein.	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.962
W2RLB2_9EURO	W2SBS8_9EURO	W2RLB2	W2SBS8	RING-type domain-containing protein.	UBX domain-containing protein.	0.782