(73 nodes) Fructose and mannose metabolism network (Cyphellophora europaea)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	W2SEJ5_9EURO	Uncharacterized protein. (416 aa)
	W2SED7_9EURO	Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (360 aa)
	W2SDR1_9EURO	Ribose 5-phosphate isomerase. (164 aa)
	W2SDC3_9EURO	Triosephosphate isomerase. (292 aa)
	W2SD70_9EURO	Uncharacterized protein. (254 aa)
	W2SD83_9EURO	Uncharacterized protein. (244 aa)
	W2RMG7_9EURO	Uncharacterized protein. (247 aa)
	W2RP12_9EURO	Uncharacterized protein. (406 aa)
	W2RP14_9EURO	Uncharacterized protein. (518 aa)
	W2RP71_9EURO	ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (794 aa)
	W2RPA9_9EURO	Uncharacterized protein. (409 aa)
	W2RPC9_9EURO	Uncharacterized protein. (238 aa)
	W2RQ20_9EURO	FBPase domain-containing protein; Belongs to the FBPase class 1 family. (359 aa)
	W2RQS9_9EURO	Phosphomannomutase; Involved in the synthesis of the GDP-mannose and dolichol- phosphate-mannose required for a number of critical mannosyl transfer reactions. (266 aa)
	W2RSB9_9EURO	NTP_transferase domain-containing protein. (439 aa)
	W2RSK2_9EURO	Uncharacterized protein. (308 aa)
	W2RSX1_9EURO	Uncharacterized protein. (351 aa)
	W2RTL1_9EURO	Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (285 aa)
	W2RTW7_9EURO	Uncharacterized protein. (260 aa)
	W2RU25_9EURO	Phosphotransferase. (492 aa)
	W2RU27_9EURO	Uncharacterized protein. (285 aa)
	W2RUD4_9EURO	Uncharacterized protein. (323 aa)
	W2RUK8_9EURO	Nudix hydrolase domain-containing protein. (296 aa)
	W2RUP9_9EURO	Uncharacterized protein. (645 aa)
	W2RV09_9EURO	Uncharacterized protein. (809 aa)
	W2RVS4_9EURO	L-xylulose reductase. (274 aa)
	W2RWM3_9EURO	Phosphotransferase. (492 aa)
	W2RWQ3_9EURO	Uncharacterized protein. (294 aa)
	W2RWY9_9EURO	Uncharacterized protein. (705 aa)
	W2RY06_9EURO	Uncharacterized protein. (282 aa)
	W2RY17_9EURO	6PF2K domain-containing protein. (541 aa)
	W2RY59_9EURO	Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (293 aa)
	W2RY93_9EURO	Uncharacterized protein. (384 aa)
	W2RYA2_9EURO	Nudix hydrolase domain-containing protein. (281 aa)
	W2RYJ8_9EURO	Uncharacterized protein. (567 aa)
	W2RZI4_9EURO	Dihydroxyacetone kinase. (601 aa)
	W2RZY3_9EURO	Amidohydro-rel domain-containing protein. (351 aa)
	W2S028_9EURO	Uncharacterized protein. (259 aa)
	W2RME5_9EURO	6PF2K domain-containing protein. (423 aa)
	W2RKK9_9EURO	Uncharacterized protein. (251 aa)
	W2RKI6_9EURO	Uncharacterized protein. (253 aa)
	W2RKG2_9EURO	Uncharacterized protein. (275 aa)
	EFM6	Protein-lysine N-methyltransferase EFM6; S-adenosyl-L-methionine-dependent protein-lysine N- methyltransferase that methylates elongation factor 1-alpha. Belongs to the class I-like SAM-binding methyltransferase superfamily. METTL21 family. EFM6 subfamily. (240 aa)
	W2S049_9EURO	Uncharacterized protein. (396 aa)
	W2S0R3_9EURO	DhaK domain-containing protein. (459 aa)
	W2S0W5_9EURO	Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (176 aa)
	W2S122_9EURO	Phosphotransferase. (456 aa)
	W2S262_9EURO	Uncharacterized protein. (429 aa)
	W2S2G9_9EURO	Uncharacterized protein. (276 aa)
	W2S2L8_9EURO	Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (134 aa)
	W2S2W0_9EURO	Phosphotransferase. (520 aa)
	W2S305_9EURO	Uncharacterized protein. (229 aa)
	W2S3D2_9EURO	Uncharacterized protein. (255 aa)
	W2S3V4_9EURO	Mannose-1-phosphate guanyltransferase. (364 aa)
	W2S4B8_9EURO	N2,N2-dimethylguanosine tRNA methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family. (698 aa)
	W2S4F3_9EURO	PfkB domain-containing protein. (355 aa)
	W2S4Z2_9EURO	Uncharacterized protein. (216 aa)
	W2S698_9EURO	Uncharacterized protein. (676 aa)
	W2S773_9EURO	Mannose-6-phosphate isomerase. (436 aa)
	W2S7E6_9EURO	PKS_ER domain-containing protein. (437 aa)
	W2S8C1_9EURO	Triosephosphate isomerase. (251 aa)
	W2S7J4_9EURO	Uncharacterized protein. (294 aa)
	W2S8V7_9EURO	Phosphotransferase. (589 aa)
	W2S9G4_9EURO	Uncharacterized protein. (487 aa)
	W2SAU5_9EURO	Uncharacterized protein. (318 aa)
	W2SB98_9EURO	FBPase domain-containing protein. (365 aa)
	W2SBI5_9EURO	Uncharacterized protein. (273 aa)
	W2SC73_9EURO	Uncharacterized protein. (258 aa)
	W2SCU6_9EURO	Uncharacterized protein. (388 aa)
	W2SCW4_9EURO	Uncharacterized protein. (500 aa)
	W2SD16_9EURO	Mannose-6-phosphate isomerase, class I. (405 aa)
	W2SD49_9EURO	Uncharacterized protein. (277 aa)
	W2SEQ7_9EURO	Uncharacterized protein. (347 aa)

Your Current Organism:

Cyphellophora europaea

NCBI taxonomy Id: 1220924
Other names: C. europaea CBS 101466, Cyphellophora europaea CBS 101466, Phialophora europaea CBS 101466

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EFM6	W2RME5_9EURO	W2RJ18	W2RME5	Protein-lysine N-methyltransferase EFM6; S-adenosyl-L-methionine-dependent protein-lysine N- methyltransferase that methylates elongation factor 1-alpha. Belongs to the class I-like SAM-binding methyltransferase superfamily. METTL21 family. EFM6 subfamily.	6PF2K domain-containing protein.	0.497
EFM6	W2RQ20_9EURO	W2RJ18	W2RQ20	Protein-lysine N-methyltransferase EFM6; S-adenosyl-L-methionine-dependent protein-lysine N- methyltransferase that methylates elongation factor 1-alpha. Belongs to the class I-like SAM-binding methyltransferase superfamily. METTL21 family. EFM6 subfamily.	FBPase domain-containing protein; Belongs to the FBPase class 1 family.	0.451
EFM6	W2RY17_9EURO	W2RJ18	W2RY17	Protein-lysine N-methyltransferase EFM6; S-adenosyl-L-methionine-dependent protein-lysine N- methyltransferase that methylates elongation factor 1-alpha. Belongs to the class I-like SAM-binding methyltransferase superfamily. METTL21 family. EFM6 subfamily.	6PF2K domain-containing protein.	0.497
EFM6	W2S698_9EURO	W2RJ18	W2S698	Protein-lysine N-methyltransferase EFM6; S-adenosyl-L-methionine-dependent protein-lysine N- methyltransferase that methylates elongation factor 1-alpha. Belongs to the class I-like SAM-binding methyltransferase superfamily. METTL21 family. EFM6 subfamily.	Uncharacterized protein.	0.497
EFM6	W2SB98_9EURO	W2RJ18	W2SB98	Protein-lysine N-methyltransferase EFM6; S-adenosyl-L-methionine-dependent protein-lysine N- methyltransferase that methylates elongation factor 1-alpha. Belongs to the class I-like SAM-binding methyltransferase superfamily. METTL21 family. EFM6 subfamily.	FBPase domain-containing protein.	0.451
W2RKG2_9EURO	W2S7E6_9EURO	W2RKG2	W2S7E6	Uncharacterized protein.	PKS_ER domain-containing protein.	0.563
W2RKG2_9EURO	W2S7J4_9EURO	W2RKG2	W2S7J4	Uncharacterized protein.	Uncharacterized protein.	0.560
W2RKG2_9EURO	W2SBI5_9EURO	W2RKG2	W2SBI5	Uncharacterized protein.	Uncharacterized protein.	0.558
W2RKG2_9EURO	W2SCU6_9EURO	W2RKG2	W2SCU6	Uncharacterized protein.	Uncharacterized protein.	0.760
W2RKG2_9EURO	W2SEJ5_9EURO	W2RKG2	W2SEJ5	Uncharacterized protein.	Uncharacterized protein.	0.563
W2RKI6_9EURO	W2S7E6_9EURO	W2RKI6	W2S7E6	Uncharacterized protein.	PKS_ER domain-containing protein.	0.459
W2RKI6_9EURO	W2SCU6_9EURO	W2RKI6	W2SCU6	Uncharacterized protein.	Uncharacterized protein.	0.459
W2RKI6_9EURO	W2SEJ5_9EURO	W2RKI6	W2SEJ5	Uncharacterized protein.	Uncharacterized protein.	0.459
W2RME5_9EURO	EFM6	W2RME5	W2RJ18	6PF2K domain-containing protein.	Protein-lysine N-methyltransferase EFM6; S-adenosyl-L-methionine-dependent protein-lysine N- methyltransferase that methylates elongation factor 1-alpha. Belongs to the class I-like SAM-binding methyltransferase superfamily. METTL21 family. EFM6 subfamily.	0.497
W2RME5_9EURO	W2RP71_9EURO	W2RME5	W2RP71	6PF2K domain-containing protein.	ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.	0.860
W2RME5_9EURO	W2RQ20_9EURO	W2RME5	W2RQ20	6PF2K domain-containing protein.	FBPase domain-containing protein; Belongs to the FBPase class 1 family.	0.823
W2RME5_9EURO	W2RSX1_9EURO	W2RME5	W2RSX1	6PF2K domain-containing protein.	Uncharacterized protein.	0.497
W2RME5_9EURO	W2RTL1_9EURO	W2RME5	W2RTL1	6PF2K domain-containing protein.	Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family.	0.509
W2RME5_9EURO	W2RU25_9EURO	W2RME5	W2RU25	6PF2K domain-containing protein.	Phosphotransferase.	0.814
W2RME5_9EURO	W2RWM3_9EURO	W2RME5	W2RWM3	6PF2K domain-containing protein.	Phosphotransferase.	0.830