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ANC76680.1 ANC76680.1 ANC79013.1 ANC79013.1 ANC79466.1 ANC79466.1 ANC78615.1 ANC78615.1 hisD hisD ANC78407.1 ANC78407.1 ANC78370.1 ANC78370.1 ANC78329.1 ANC78329.1 ANC78290.1 ANC78290.1 ANC78168.1 ANC78168.1 ANC78133.1 ANC78133.1 ANC78124.1 ANC78124.1 mdh mdh ilvC ilvC leuB leuB aroE aroE ANC77719.1 ANC77719.1 gpsA gpsA ANC77483.1 ANC77483.1 zwf zwf tdh tdh dxr dxr murB murB ANC76763.1 ANC76763.1 ANC76509.1 ANC76509.1 ANC75984.1 ANC75984.1 ANC75891.1 ANC75891.1 ANC75800.1 ANC75800.1 guaB guaB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ANC76680.1NAD(P)-dependent oxidoreductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. (271 aa)
ANC79013.13-hydroxybutyryl-CoA dehydrogenase; Converts (S)-3-hydroxybutanoyl-CoA to 3-acetoacetyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (284 aa)
ANC79466.1Dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (349 aa)
ANC78615.1UDP-glucose 6-dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (433 aa)
hisDHistidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (423 aa)
ANC78407.1Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (430 aa)
ANC78370.13-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (798 aa)
ANC78329.1D-glycerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (321 aa)
ANC78290.1Butanol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (387 aa)
ANC78168.1Acetoin dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (210 aa)
ANC78133.1Malate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (413 aa)
ANC78124.1Isocitrate dehydrogenase (NADP(+)); Converts isocitrate to alpha ketoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology. (422 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (312 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (341 aa)
leuB3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (364 aa)
aroEHypothetical protein; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (275 aa)
ANC77719.1Phosphoglycerate dehydrogenase; Catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (530 aa)
gpsAGlycerol-3-phosphate dehydrogenase; Catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (341 aa)
ANC77483.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (64 aa)
zwfGlucose-6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (500 aa)
tdhL-threonine 3-dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2- amino-3-ketobutyrate; Belongs to the zinc-containing alcohol dehydrogenase family. (342 aa)
dxr1-deoxy-D-xylulose-5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (385 aa)
murBUDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. (303 aa)
ANC76763.1Hypothetical protein; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (295 aa)
ANC76509.16-phosphogluconate dehydrogenase; Similar to full-length Gnd, these proteins seems to have a truncated C-terminal 6PGD domainin; in Methylobacillus flagellatus this gene is essential for NAD+-dependent oxidation of 6-phosphogluconate; Derived by automated computational analysis using gene prediction method: Protein Homology. (298 aa)
ANC75984.13-hydroxybutyryl-CoA dehydrogenase; Converts (S)-3-hydroxybutanoyl-CoA to 3-acetoacetyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (290 aa)
ANC75891.1Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (362 aa)
ANC75800.13-phosphoglycerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (316 aa)
guaBIMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (485 aa)
Your Current Organism:
Fictibacillus phosphorivorans
NCBI taxonomy Id: 1221500
Other names: Bacillus sp. Ca7, CCM 8426, F. phosphorivorans, Fictibacillus phosphorivorans Glaeser et al. 2013, LMG 27063, LMG:27063, strain Ca7
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