STRINGSTRING
hemC hemC ANC75544.1 ANC75544.1 hemL hemL ANC75958.1 ANC75958.1 hemE hemE hemH hemH ANC79259.1 ANC79259.1 ANC79329.1 ANC79329.1 ctaB ctaB ANC77119.1 ANC77119.1 ANC77120.1 ANC77120.1 ANC77121.1 ANC77121.1 ctaB-2 ctaB-2 ANC78010.1 ANC78010.1 hemL-2 hemL-2 ANC78045.1 ANC78045.1 ANC78046.1 ANC78046.1 hemA hemA ANC79041.1 ANC79041.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
hemCHydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (310 aa)
ANC75544.1Antibiotic biosynthesis monooxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (101 aa)
hemLGlutamate-1-semialdehyde aminotransferase; Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway; Derived by automated computational analysis using gene prediction method: Protein Homology. (428 aa)
ANC75958.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (163 aa)
hemEUroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. (342 aa)
hemHFerrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (313 aa)
ANC79259.1Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. (468 aa)
ANC79329.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (280 aa)
ctaBProtoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group; Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily. (297 aa)
ANC77119.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (212 aa)
ANC77120.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (250 aa)
ANC77121.1uroporphyrin-III methyltransferase; Catalyzes 2 sequential methylations, the formation of precorrin-1 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and uroporphyrin III, and the formation of precorrin-2 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and precorrin-1; Derived by automated computational analysis using gene prediction method: Protein Homology. (261 aa)
ctaB-2Protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group; Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily. (304 aa)
ANC78010.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (63 aa)
hemL-2Glutamate-1-semialdehyde aminotransferase; Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate; Derived by automated computational analysis using gene prediction method: Protein Homology. (428 aa)
ANC78045.1Delta-aminolevulinic acid dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ALAD family. (323 aa)
ANC78046.1Hypothetical protein; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. (250 aa)
hemAglutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (455 aa)
ANC79041.1Heme-dependent peroxidase; May function as heme-dependent peroxidase. (247 aa)
Your Current Organism:
Fictibacillus phosphorivorans
NCBI taxonomy Id: 1221500
Other names: Bacillus sp. Ca7, CCM 8426, F. phosphorivorans, Fictibacillus phosphorivorans Glaeser et al. 2013, LMG 27063, LMG:27063, strain Ca7
Server load: low (20%) [HD]