STRINGSTRING
EMF02640.1 EMF02640.1 EMF02477.1 EMF02477.1 EMF02503.1 EMF02503.1 EMF02504.1 EMF02504.1 EMF02505.1 EMF02505.1 EMF02506.1 EMF02506.1 EMF02507.1 EMF02507.1 EMF02508.1 EMF02508.1 EMF02281.1 EMF02281.1 EMF02306.1 EMF02306.1 EMF02118.1 EMF02118.1 EMF02146.1 EMF02146.1 EMF01908.1 EMF01908.1 EMF01914.1 EMF01914.1 EMF01849.1 EMF01849.1 EMF01758.1 EMF01758.1 EMF01611.1 EMF01611.1 EMF01512.1 EMF01512.1 EMF01513.1 EMF01513.1 EMF01514.1 EMF01514.1 EMF01515.1 EMF01515.1 EMF01517.1 EMF01517.1 EMF01426.1 EMF01426.1 EMF01356.1 EMF01356.1 EMF01357.1 EMF01357.1 EMF01358.1 EMF01358.1 EMF01359.1 EMF01359.1 EMF01360.1 EMF01360.1 EMF01399.1 EMF01399.1 EMF01313.1 EMF01313.1 EMF01314.1 EMF01314.1 EMF00947.1 EMF00947.1 EMF00973.1 EMF00973.1 EMF00977.1 EMF00977.1 EMF00788.1 EMF00788.1 EMF00465.1 EMF00465.1 EMF00455.1 EMF00455.1 EMF00350.1 EMF00350.1 EMF00291.1 EMF00291.1 EMF00194.1 EMF00194.1 EMF00081.1 EMF00081.1 EMF00082.1 EMF00082.1 EMF00108.1 EMF00108.1 EMF00109.1 EMF00109.1 EMF00110.1 EMF00110.1 EMF00111.1 EMF00111.1 EMF00112.1 EMF00112.1 EME99967.1 EME99967.1 EME99850.1 EME99850.1 EME99730.1 EME99730.1 EME99691.1 EME99691.1 EME99646.1 EME99646.1 EME99559.1 EME99559.1 EME99444.1 EME99444.1 EME99470.1 EME99470.1 arc arc EME99472.1 EME99472.1 pup pup prcB prcB prcA prcA EME99433.1 EME99433.1 EME99203.1 EME99203.1 alaS-2 alaS-2 EME99013.1 EME99013.1 EME98677.1 EME98677.1 EME98679.1 EME98679.1 EME98621.1 EME98621.1 EME98627.1 EME98627.1 EME98545.1 EME98545.1 EME98425.1 EME98425.1 EME98353.1 EME98353.1 EME98372.1 EME98372.1 EME98158.1 EME98158.1 EME98123.1 EME98123.1 EME97934.1 EME97934.1 EME97945.1 EME97945.1 EME97946.1 EME97946.1 EME97947.1 EME97947.1 EME97948.1 EME97948.1 EME97895.1 EME97895.1 EME97752.1 EME97752.1 EME97663.1 EME97663.1 EME97553.1 EME97553.1 EME97531.1 EME97531.1 EME97307.1 EME97307.1 EME97192.1 EME97192.1 EME97013.1 EME97013.1 EME97014.1 EME97014.1 EME96985.1 EME96985.1 EME96904.1 EME96904.1 EME96843.1 EME96843.1 EME96720.1 EME96720.1 EME96660.1 EME96660.1 EME96661.1 EME96661.1 EME96612.1 EME96612.1 EME96461.1 EME96461.1 EME96357.1 EME96357.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
EMF02640.1Hypothetical protein. (218 aa)
EMF02477.1COG2272 Carboxylesterase type B; Belongs to the type-B carboxylesterase/lipase family. (497 aa)
EMF02503.1Hypothetical protein. (246 aa)
EMF02504.1COG2304 Uncharacterized protein containing a von Willebrand factor type A (vWA) domain. (422 aa)
EMF02505.1Lipoprotein. (261 aa)
EMF02506.1Hypothetical protein. (284 aa)
EMF02507.1Hypothetical protein. (716 aa)
EMF02508.1Hypothetical protein. (296 aa)
EMF02281.1COG2132 Putative multicopper oxidases. (534 aa)
EMF02306.1COG5398 Heme oxygenase. (223 aa)
EMF02118.1Hypothetical protein; COG2319 FOG: WD40 repeat. (1317 aa)
EMF02146.1COG0657 Esterase/lipase. (305 aa)
EMF01908.1Histidine kinase; COG0642 Signal transduction histidine kinase. (746 aa)
EMF01914.1Endonuclease. (911 aa)
EMF01849.1Hypothetical protein. (187 aa)
EMF01758.1COG0553 Superfamily II DNA/RNA helicases, SNF2 family. (936 aa)
EMF01611.1Hypothetical protein. (226 aa)
EMF01512.1Hypothetical protein. (424 aa)
EMF01513.1WD-40 repeat-containing protein; COG2319 FOG: WD40 repeat. (317 aa)
EMF01514.1Hypothetical protein. (574 aa)
EMF01515.1Hypothetical protein. (1556 aa)
EMF01517.1Hypothetical protein. (893 aa)
EMF01426.1Aminopeptidase; COG2234 Predicted aminopeptidases. (507 aa)
EMF01356.1Hypothetical protein. (163 aa)
EMF01357.1ATPase AAA; COG0719 ABC-type transport system involved in Fe-S cluster assembly, permease component. (810 aa)
EMF01358.1Hypothetical protein. (223 aa)
EMF01359.1COG3217 Uncharacterized Fe-S protein. (263 aa)
EMF01360.1Hypothetical protein. (174 aa)
EMF01399.1SARP family transcriptional regulator. (562 aa)
EMF01313.1Beta-lactamase; COG0491 Zn-dependent hydrolases, including glyoxylases. (304 aa)
EMF01314.1COG2272 Carboxylesterase type B; Belongs to the type-B carboxylesterase/lipase family. (510 aa)
EMF00947.1Oxidoreductase; COG2303 Choline dehydrogenase and related flavoproteins. (521 aa)
EMF00973.1Transcriptional regulator, XRE family protein. (531 aa)
EMF00977.1Aminopeptidase; COG2234 Predicted aminopeptidases. (505 aa)
EMF00788.1Hypothetical protein. (214 aa)
EMF00465.1COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain. (500 aa)
EMF00455.1Hypothetical protein. (502 aa)
EMF00350.1Putative calcium-binding protein. (171 aa)
EMF00291.1Putative acetoin utilization protein; COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein. (390 aa)
EMF00194.1Protease; COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain. (410 aa)
EMF00081.1COG0545 FKBP-type peptidyl-prolyl cis-trans isomerases 1. (362 aa)
EMF00082.1COG0545 FKBP-type peptidyl-prolyl cis-trans isomerases 1; FK-506 binding protein. (124 aa)
EMF00108.1Hypothetical protein; COG3616 Predicted amino acid aldolase or racemase. (405 aa)
EMF00109.1Hypothetical protein. (281 aa)
EMF00110.1COG1404 Subtilisin-like serine proteases. (371 aa)
EMF00111.1Hypothetical protein. (244 aa)
EMF00112.1Aquaporin Z; COG0580 Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family); Belongs to the MIP/aquaporin (TC 1.A.8) family. (294 aa)
EME99967.1Proteinase inhibitor I4 serpin; COG4826 Serine protease inhibitor; Belongs to the serpin family. (402 aa)
EME99850.1Plastocyanin-like protein; COG3794 Plastocyanin. (81 aa)
EME99730.1COG1199 Rad3-related DNA helicases. (670 aa)
EME99691.1Peptidase C14 caspase catalytic subunit p20; COG4249 Uncharacterized protein containing caspase domain. (385 aa)
EME99646.1Hypothetical protein. (547 aa)
EME99559.1COG2183 Transcriptional accessory protein. (518 aa)
EME99444.1Hypothetical protein. (268 aa)
EME99470.1COG1141 Ferredoxin. (111 aa)
arcATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. (588 aa)
EME99472.1Pup ligase. (503 aa)
pupUbiquitin-like protein pup; Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation. (72 aa)
prcB20S proteasome subunit beta; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1B family. (281 aa)
prcA20S proteasome subunits A and B; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1A family. (250 aa)
EME99433.1Hypothetical protein. (179 aa)
EME99203.1alpha-N-acetylglucosaminidase. (763 aa)
alaS-2alanyl-tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (889 aa)
EME99013.1Hypothetical protein. (183 aa)
EME98677.1Secretory serine protease. (235 aa)
EME98679.1Cholesterol oxidase; COG2303 Choline dehydrogenase and related flavoproteins. (533 aa)
EME98621.1COG2272 Carboxylesterase type B; Belongs to the type-B carboxylesterase/lipase family. (556 aa)
EME98627.1Ankyrin-like protein; COG0666 FOG: Ankyrin repeat. (147 aa)
EME98545.1COG5640 Secreted trypsin-like serine protease. (290 aa)
EME98425.1FAD-linked oxidoreductase; COG0277 FAD/FMN-containing dehydrogenases. (401 aa)
EME98353.1Hypothetical protein. (301 aa)
EME98372.1Bacterioferritin; Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex; Belongs to the bacterioferritin family. (163 aa)
EME98158.1COG3236 Uncharacterized protein conserved in bacteria. (196 aa)
EME98123.1SNF2/RAD54 family helicase. (231 aa)
EME97934.1COG1061 DNA or RNA helicases of superfamily II. (565 aa)
EME97945.1Hypothetical protein; COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases. (97 aa)
EME97946.1Hypothetical protein. (421 aa)
EME97947.1Hypothetical protein. (365 aa)
EME97948.1Hypothetical protein. (132 aa)
EME97895.1Hypothetical protein. (244 aa)
EME97752.1COG1409 Predicted phosphohydrolases. (574 aa)
EME97663.1Hypothetical protein. (210 aa)
EME97553.1Tex-like protein; COG2183 Transcriptional accessory protein. (273 aa)
EME97531.1COG5640 Secreted trypsin-like serine protease. (276 aa)
EME97307.1Hypothetical protein; COG0666 FOG: Ankyrin repeat. (148 aa)
EME97192.1Hyaluronidase. (1043 aa)
EME97013.1Hypothetical protein; COG0572 Uridine kinase. (202 aa)
EME97014.1ATPase AAA; COG0457 FOG: TPR repeat. (613 aa)
EME96985.1XRE family transcriptional regulator; COG3903 Predicted ATPase. (784 aa)
EME96904.1Bilirubin oxidase; COG2132 Putative multicopper oxidases. (159 aa)
EME96843.1Putative calmodulin-like protein; COG5126 Ca2+-binding protein (EF-Hand superfamily). (71 aa)
EME96720.1Peptidase S1 and S6 chymotrypsin/Hap; COG5640 Secreted trypsin-like serine protease. (267 aa)
EME96660.1COG0553 Superfamily II DNA/RNA helicases, SNF2 family. (800 aa)
EME96661.1SWIM zinc finger domain-containing protein. (282 aa)
EME96612.1NAD-binding D-isomer specific 2-hydroxyacid dehydrogenase; COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (311 aa)
EME96461.1COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain. (429 aa)
EME96357.1Peptidase S1 and S6 chymotrypsin/Hap; COG5640 Secreted trypsin-like serine protease. (258 aa)
Your Current Organism:
Streptomyces mobaraensis
NCBI taxonomy Id: 1223523
Other names: S. mobaraensis NBRC 13819 = DSM 40847, Streptomyces mobaraensis ATCC 29032, Streptomyces mobaraensis DSM 40847, Streptomyces mobaraensis DSM 40847 = NBRC 13819, Streptomyces mobaraensis IFO 13819, Streptomyces mobaraensis NBRC 13819, Streptomyces mobaraensis NBRC 13819 = DSM 40847, Streptomyces mobaraensis NRRL B-3729
Server load: low (22%) [HD]