STRINGSTRING
EME96395.1 EME96395.1 EMF02672.1 EMF02672.1 EMF02185.1 EMF02185.1 EMF02334.1 EMF02334.1 EMF01814.1 EMF01814.1 EMF01707.1 EMF01707.1 EMF01155.1 EMF01155.1 EMF01198.1 EMF01198.1 pdxT pdxT EMF00516.1 EMF00516.1 cobQ cobQ cobB cobB EMF00451.1 EMF00451.1 EMF00136.1 EMF00136.1 EMF00102.1 EMF00102.1 guaA guaA EME99127.1 EME99127.1 purQ purQ EME98762.1 EME98762.1 carA carA EME98667.1 EME98667.1 EME98369.1 EME98369.1 EME97026.1 EME97026.1 EME96983.1 EME96983.1 EME96900.1 EME96900.1 pyrG pyrG hisH hisH EME96560.1 EME96560.1 EME96526.1 EME96526.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
EME96395.1COG1619 Uncharacterized proteins, homologs of microcin C7 resistance protein MccF. (350 aa)
EMF02672.1COG4977 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain. (339 aa)
EMF02185.1COG4977 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain. (317 aa)
EMF02334.1COG4977 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain. (324 aa)
EMF01814.1COG0512 Anthranilate/para-aminobenzoate synthases component II. (212 aa)
EMF01707.1COG0512 Anthranilate/para-aminobenzoate synthases component II. (707 aa)
EMF01155.1COG0693 Putative intracellular protease/amidase. (181 aa)
EMF01198.1Catalase; Serves to protect cells from the toxic effects of hydrogen peroxide. (706 aa)
pdxTGlutamine amidotransferase subunit PdxT; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. (197 aa)
EMF00516.1Hypothetical protein; COG0693 Putative intracellular protease/amidase. (264 aa)
cobQCobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. (606 aa)
cobBCobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. (454 aa)
EMF00451.1COG4977 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain. (350 aa)
EMF00136.1Hypothetical protein. (679 aa)
EMF00102.1Peptidase C26; COG2071 Predicted glutamine amidotransferases. (266 aa)
guaAGMP synthase; Catalyzes the synthesis of GMP from XMP. (531 aa)
EME99127.1COG4977 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain. (355 aa)
purQPhosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] (226 aa)
EME98762.1Hypothetical protein; COG0504 CTP synthase (UTP-ammonia lyase). (245 aa)
carACOG0505 Carbamoylphosphate synthase small subunit; Belongs to the CarA family. (385 aa)
EME98667.1CobB/CobQ domain-containing protein glutamine amidotransferase; COG3442 Predicted glutamine amidotransferase. (242 aa)
EME98369.1COG0147 Anthranilate/para-aminobenzoate synthases component I. (653 aa)
EME97026.1A-factor-responsive transcriptional activator; COG4977 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain. (459 aa)
EME96983.1COG4977 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain. (326 aa)
EME96900.1Transcriptional activator FtrA; COG4977 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain. (232 aa)
pyrGCTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (550 aa)
hisHImidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (212 aa)
EME96560.1COG4977 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain. (317 aa)
EME96526.1COG4977 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain. (329 aa)
Your Current Organism:
Streptomyces mobaraensis
NCBI taxonomy Id: 1223523
Other names: S. mobaraensis NBRC 13819 = DSM 40847, Streptomyces mobaraensis ATCC 29032, Streptomyces mobaraensis DSM 40847, Streptomyces mobaraensis DSM 40847 = NBRC 13819, Streptomyces mobaraensis IFO 13819, Streptomyces mobaraensis NBRC 13819, Streptomyces mobaraensis NBRC 13819 = DSM 40847, Streptomyces mobaraensis NRRL B-3729
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.