STRINGSTRING
EMF02228.1 EMF02228.1 EMF01792.1 EMF01792.1 EMF01804.1 EMF01804.1 EMF01728.1 EMF01728.1 EMF01467.1 EMF01467.1 EMF01241.1 EMF01241.1 dxs dxs ispG ispG htpX htpX EMF01097.1 EMF01097.1 ispH ispH EMF01051.1 EMF01051.1 EMF00816.1 EMF00816.1 dxs-2 dxs-2 ispD ispD ispF ispF EMF00070.1 EMF00070.1 EME99944.1 EME99944.1 trmD trmD EME99765.1 EME99765.1 EME99512.1 EME99512.1 EME99542.1 EME99542.1 EME98964.1 EME98964.1 dxr dxr ispG-2 ispG-2 htpX-2 htpX-2 EME98029.1 EME98029.1 EME97958.1 EME97958.1 EME97856.1 EME97856.1 EME97729.1 EME97729.1 idi idi EME97570.1 EME97570.1 EME97572.1 EME97572.1 ispG-3 ispG-3 EME97485.1 EME97485.1 ispG-4 ispG-4 ispE ispE EME96811.1 EME96811.1 ispH-2 ispH-2 EME96781.1 EME96781.1 ispG-5 ispG-5 dxs-3 dxs-3 EME96578.1 EME96578.1 EME96418.1 EME96418.1 EME96393.1 EME96393.1 EME96296.1 EME96296.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
EMF02228.1Peptidase M48 Ste24p; COG0501 Zn-dependent protease with chaperone function. (312 aa)
EMF01792.1Hypothetical protein; COG0501 Zn-dependent protease with chaperone function. (310 aa)
EMF01804.1Peptidase M48 Ste24p; COG0501 Zn-dependent protease with chaperone function. (309 aa)
EMF01728.1Hypothetical protein. (140 aa)
EMF01467.1Hypothetical protein; COG0501 Zn-dependent protease with chaperone function. (525 aa)
EMF01241.1Polyprenyl synthetase; COG0142 Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family. (348 aa)
dxs1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (641 aa)
ispG4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; COG0821 Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis. (186 aa)
htpXHeat shock protein HtpX; COG0501 Zn-dependent protease with chaperone function; Belongs to the peptidase M48B family. (288 aa)
EMF01097.1Polyprenyl synthetase; COG0142 Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family. (336 aa)
ispH4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (313 aa)
EMF01051.1Undecaprenyl pyrophosphate synthetase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. (253 aa)
EMF00816.1COG0726 Predicted xylanase/chitin deacetylase. (265 aa)
dxs-21-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (662 aa)
ispD2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). (269 aa)
ispF2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). (153 aa)
EMF00070.1COG0501 Zn-dependent protease with chaperone function. (379 aa)
EME99944.1Secreted protein; COG0726 Predicted xylanase/chitin deacetylase. (231 aa)
trmDtRNA (guanine-N(1)-)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family. (271 aa)
EME99765.1UDP phosphate synthetase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. (275 aa)
EME99512.1COG0726 Predicted xylanase/chitin deacetylase. (268 aa)
EME99542.1COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes. (179 aa)
EME98964.1Hypothetical protein. (140 aa)
dxr1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (426 aa)
ispG-24-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; COG0821 Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis. (38 aa)
htpX-2Heat shock protein HtpX; COG0501 Zn-dependent protease with chaperone function; Belongs to the peptidase M48B family. (286 aa)
EME98029.1COG0726 Predicted xylanase/chitin deacetylase. (220 aa)
EME97958.1COG0726 Predicted xylanase/chitin deacetylase. (278 aa)
EME97856.1Acyltransferase; COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (391 aa)
EME97729.1COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (406 aa)
idiIsopentenyl-diphosphate delta-isomerase; Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP). (203 aa)
EME97570.1Polyprenyl diphosphate synthase; COG0142 Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family. (354 aa)
EME97572.1Hypothetical protein; COG0775 Nucleoside phosphorylase. (218 aa)
ispG-34-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; COG0821 Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis. (48 aa)
EME97485.1Hypothetical protein; COG0501 Zn-dependent protease with chaperone function. (436 aa)
ispG-44-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; COG0821 Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis. (186 aa)
ispE4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (305 aa)
EME96811.1COG0726 Predicted xylanase/chitin deacetylase. (255 aa)
ispH-24-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (444 aa)
EME96781.1Polyprenyl synthetase; COG0142 Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family. (359 aa)
ispG-54-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (385 aa)
dxs-31-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (610 aa)
EME96578.1Putative secreted protein; COG0726 Predicted xylanase/chitin deacetylase. (301 aa)
EME96418.1COG0726 Predicted xylanase/chitin deacetylase. (316 aa)
EME96393.1Hydrolase; COG0726 Predicted xylanase/chitin deacetylase. (259 aa)
EME96296.1Putative lipoprotein; COG0726 Predicted xylanase/chitin deacetylase. (199 aa)
Your Current Organism:
Streptomyces mobaraensis
NCBI taxonomy Id: 1223523
Other names: S. mobaraensis NBRC 13819 = DSM 40847, Streptomyces mobaraensis ATCC 29032, Streptomyces mobaraensis DSM 40847, Streptomyces mobaraensis DSM 40847 = NBRC 13819, Streptomyces mobaraensis IFO 13819, Streptomyces mobaraensis NBRC 13819, Streptomyces mobaraensis NBRC 13819 = DSM 40847, Streptomyces mobaraensis NRRL B-3729
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