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ppc ppc gltA gltA glcB glcB AHI22338.1 AHI22338.1 fumC fumC AHI22514.1 AHI22514.1 AHI22515.1 AHI22515.1 AHI22833.1 AHI22833.1 ppc-2 ppc-2 mqo mqo mdh mdh AHI23562.1 AHI23562.1 AHI23563.1 AHI23563.1 pckG pckG
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ppcPhosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (868 aa)
gltACOG0372 Citrate synthase; Belongs to the citrate synthase family. (431 aa)
glcBMalate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. (729 aa)
AHI22338.1COG2224 Isocitrate lyase. (431 aa)
fumCFumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (465 aa)
AHI22514.1COG0372 Citrate synthase; Belongs to the citrate synthase family. (390 aa)
AHI22515.1Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1140 aa)
AHI22833.1Aconitate hydratase; COG1048 Aconitase A. (938 aa)
ppc-2Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (893 aa)
mqoMalate:quinone oxidoreductase; COG0579 Predicted dehydrogenase. (498 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. (325 aa)
AHI23562.1COG1838 Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain. (208 aa)
AHI23563.1COG1951 Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain. (349 aa)
pckGPhosphoenolpyruvate carboxykinase; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. (609 aa)
Your Current Organism:
Corynebacterium vitaeruminis
NCBI taxonomy Id: 1224164
Other names: C. vitaeruminis DSM 20294, Corynebacterium vitaeruminis ATCC 10234, Corynebacterium vitaeruminis CIP 82.7, Corynebacterium vitaeruminis DSM 20294
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