STRINGSTRING
sdaA sdaA cysE cysE cysK cysK metB metB ilvA ilvA serB serB thrC thrC metM metM metZ metZ serC serC thrB thrB cysS cysS
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
sdaAL-serine dehydratase; Identified by similarity to GP:3402236; match to protein family HMM PF03313; match to protein family HMM PF03315; match to protein family HMM TIGR00720; Belongs to the iron-sulfur dependent L-serine dehydratase family. (461 aa)
cysESerine acetyltransferase; Identified by similarity to EGAD:29240; match to protein family HMM PF00132; match to protein family HMM PF06426; match to protein family HMM TIGR01172. (272 aa)
cysKCysteine synthase; Identified by similarity to EGAD:160962; match to protein family HMM PF00291; match to protein family HMM TIGR01136; match to protein family HMM TIGR01139; Belongs to the cysteine synthase/cystathionine beta- synthase family. (310 aa)
metBCystathionine gamma-synthase; Identified by similarity to EGAD:109991; match to protein family HMM PF01053. (385 aa)
ilvAThreonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (508 aa)
serBPhosphoserine phosphatase; Identified by similarity to EGAD:8936; match to protein family HMM PF00702; match to protein family HMM TIGR00338; match to protein family HMM TIGR01488. (277 aa)
thrCThreonine synthase; Identified by similarity to EGAD:6267; match to protein family HMM PF00291; match to protein family HMM TIGR00260. (469 aa)
metMHomoserine dehydrogenase; Identified by similarity to EGAD:6746; match to protein family HMM PF00742; match to protein family HMM PF01842; match to protein family HMM PF03447. (435 aa)
metZTrans-sulfuration enzyme family protein; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. (389 aa)
serCPhosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (368 aa)
thrBHomoserine kinase; Identified by similarity to GP:3089616; match to protein family HMM PF01636; match to protein family HMM TIGR00938; Belongs to the pseudomonas-type ThrB family. (305 aa)
cysScysteinyl-tRNA synthetase; Identified by similarity to EGAD:17646; match to protein family HMM PF01406; match to protein family HMM TIGR00435; Belongs to the class-I aminoacyl-tRNA synthetase family. (473 aa)
Your Current Organism:
Neisseria meningitidis
NCBI taxonomy Id: 122586
Other names: N. meningitidis MC58, Neisseria meningitidis MC58, Neisseria meningitidis serogroup B strain MC58
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