STRINGSTRING
NMB0034 NMB0034 NMB0035 NMB0035 NMB0036 NMB0036 NMB0293 NMB0293 tbp2 tbp2 tbp1 tbp1 NMB0586 NMB0586 NMB0587 NMB0587 NMB0588 NMB0588 fbpC fbpC fbpB fbpB fbpA fbpA NMB0786 NMB0786 NMB0964 NMB0964 NMB1049 NMB1049 NMB1221 NMB1221 NMB1263 NMB1263 NMB1266 NMB1266 lbpA lbpA lbpB lbpB hmbR hmbR exbD exbD exbB exbB tonB tonB NMB2137 NMB2137
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NMB0034Conserved hypothetical protein; Identified by similarity to EGAD:90733; match to protein family HMM PF03239. (279 aa)
NMB0035Conserved hypothetical protein; Identified by similarity to EGAD:90734; match to protein family HMM PF04302; Belongs to the EfeM/EfeO family. (388 aa)
NMB0036Conserved hypothetical protein; Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the tetrapyrrol ring intact. Belongs to the DyP-type peroxidase family. (421 aa)
NMB0293Putative TonB-dependent receptor; Identified by similarity to EGAD:48295; match to protein family HMM PF00593; match to protein family HMM PF07715; match to protein family HMM TIGR01783. (703 aa)
tbp2Transferrin-binding protein 2; Acts as a transferrin receptor and is required for transferrin utilization. (712 aa)
tbp1Transferrin-binding protein 1; Acts as a transferrin receptor and is required for transferrin utilization; Belongs to the TonB-dependent receptor family. (915 aa)
NMB0586Putative adhesin; Identified by similarity to EGAD:16475; match to protein family HMM PF01297; Belongs to the bacterial solute-binding protein 9 family. (304 aa)
NMB0587Membrane protein; Identified by similarity to EGAD:15708; match to protein family HMM PF00950. (291 aa)
NMB0588ABC transporter, ATP-binding protein; Identified by similarity to EGAD:153448; match to protein family HMM PF00005. (251 aa)
fbpCiron(III) ABC transporter, ATP-binding protein; Part of the ABC transporter complex FbpABC involved in Fe(3+) ions import. Responsible for energy coupling to the transport system. (352 aa)
fbpBiron(III) ABC transporter, permease protein; Identified by similarity to EGAD:40675; match to protein family HMM PF00528. (505 aa)
fbpAiron(III) ABC transporter, periplasmic binding protein; This protein may be a central component in the iron- acquisition system. (331 aa)
NMB0786Conserved hypothetical protein; Identified by similarity to EGAD:91404; match to protein family HMM PF04261; match to protein family HMM TIGR01413. (302 aa)
NMB0964TonB-dependent receptor; Probable receptor, TonB-dependent. (758 aa)
NMB1049Putative transcriptional regulator; Identified by similarity to EGAD:14640; match to protein family HMM PF00126; match to protein family HMM PF03466; Belongs to the LysR transcriptional regulatory family. (304 aa)
NMB1221Hypothetical protein; Identified by Glimmer2; putative. (135 aa)
NMB1263CobW-related protein; Identified by similarity to EGAD:156097; match to protein family HMM PF02492; match to protein family HMM PF07683. (305 aa)
NMB1266Putative zinc uptake regulation protein; Identified by similarity to EGAD:6546; Belongs to the Fur family. (158 aa)
lbpALactoferrin-binding protein A; Unknown. May be an iron-siderophore receptor. (943 aa)
lbpBIdentified by similarity to GP:3582728; match to protein family HMM PF01298. (737 aa)
hmbRHemoglobin receptor; Identified by similarity to EGAD:131251; match to protein family HMM PF00593; match to protein family HMM PF07715; match to protein family HMM TIGR01786. (791 aa)
exbDBiopolymer transport protein ExbD; Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates. (144 aa)
exbBBiopolymer transport protein ExbB; Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates. Protects ExbD from proteolytic degradation and functionally stabilizes TonB (By similarity). (220 aa)
tonBTonB protein; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Required for heme utilization and virulence. (280 aa)
NMB2137Hypothetical protein; Identified by Glimmer2; putative. (70 aa)
Your Current Organism:
Neisseria meningitidis
NCBI taxonomy Id: 122586
Other names: N. meningitidis MC58, Neisseria meningitidis MC58, Neisseria meningitidis serogroup B strain MC58
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