STRINGSTRING
SFQ68636.1 SFQ68636.1 SFQ69033.1 SFQ69033.1 SFQ69200.1 SFQ69200.1 SFQ69318.1 SFQ69318.1 SFQ69357.1 SFQ69357.1 rho rho SFQ71977.1 SFQ71977.1 argS argS SFP68909.1 SFP68909.1 SFP69097.1 SFP69097.1 rnz rnz ruvC ruvC SFP69961.1 SFP69961.1 SFP70509.1 SFP70509.1 SFP72223.1 SFP72223.1 SFP72609.1 SFP72609.1 SFP72930.1 SFP72930.1 SFP75122.1 SFP75122.1 SFP75781.1 SFP75781.1 SFP75862.1 SFP75862.1 SFP76613.1 SFP76613.1 hisS hisS SFP79303.1 SFP79303.1 SFP79541.1 SFP79541.1 SFP79569.1 SFP79569.1 gyrB gyrB topA topA SFP80271.1 SFP80271.1 SFP80892.1 SFP80892.1 SFP80910.1 SFP80910.1 xerC xerC valS valS rsmA rsmA ligA ligA SFP85347.1 SFP85347.1 SFP87041.1 SFP87041.1 SFP87344.1 SFP87344.1 SFP87485.1 SFP87485.1 alaS alaS gatB gatB SFP88293.1 SFP88293.1 SFP89865.1 SFP89865.1 gyrA gyrA trmB trmB SFP90733.1 SFP90733.1 tyrS tyrS thrS thrS SFP91342.1 SFP91342.1 SFP91404.1 SFP91404.1 SFP91479.1 SFP91479.1 SFP91707.1 SFP91707.1 dnaG dnaG leuS leuS SFP93263.1 SFP93263.1 SFP96063.1 SFP96063.1 SFP96751.1 SFP96751.1 SFP96841.1 SFP96841.1 SFP97053.1 SFP97053.1 rsmH rsmH SFQ01449.1 SFQ01449.1 SFQ01749.1 SFQ01749.1 SFQ01850.1 SFQ01850.1 SFQ03249.1 SFQ03249.1 fmt fmt dinB dinB SFQ18940.1 SFQ18940.1 ruvB ruvB SFQ19835.1 SFQ19835.1 recA recA SFQ20361.1 SFQ20361.1 pheS pheS rlmN rlmN SFQ22299.1 SFQ22299.1 uvrB uvrB SFQ23863.1 SFQ23863.1 SFQ23933.1 SFQ23933.1 SFQ24196.1 SFQ24196.1 SFQ24697.1 SFQ24697.1 cysS cysS SFQ25187.1 SFQ25187.1 SFQ25293.1 SFQ25293.1 ruvA ruvA gatA gatA rsmI rsmI radA radA SFQ27559.1 SFQ27559.1 SFQ27577.1 SFQ27577.1 polA polA SFQ28861.1 SFQ28861.1 ybeY ybeY glyQS glyQS ileS ileS rnr rnr SFQ29568.1 SFQ29568.1 gltX gltX SFQ30903.1 SFQ30903.1 truA truA SFQ31707.1 SFQ31707.1 SFQ31743.1 SFQ31743.1 uvrC uvrC SFQ34071.1 SFQ34071.1 SFQ35706.1 SFQ35706.1 SFQ37354.1 SFQ37354.1 SFQ37438.1 SFQ37438.1 mfd mfd SFQ39004.1 SFQ39004.1 SFQ39145.1 SFQ39145.1 mutS mutS SFQ39271.1 SFQ39271.1 SFQ39506.1 SFQ39506.1 recG recG SFQ40124.1 SFQ40124.1 SFQ40203.1 SFQ40203.1 nth nth SFQ41890.1 SFQ41890.1 rnpA rnpA SFQ46867.1 SFQ46867.1 mutL mutL SFQ47591.1 SFQ47591.1 lysS lysS SFQ48590.1 SFQ48590.1 SFQ48816.1 SFQ48816.1 SFQ49008.1 SFQ49008.1 SFQ49285.1 SFQ49285.1 SFQ49466.1 SFQ49466.1 SFQ49519.1 SFQ49519.1 xseB xseB SFQ50085.1 SFQ50085.1 SFQ50699.1 SFQ50699.1 SFQ50722.1 SFQ50722.1 SFQ50828.1 SFQ50828.1 SFQ51052.1 SFQ51052.1 miaA miaA SFQ51324.1 SFQ51324.1 SFQ52610.1 SFQ52610.1 SFQ52756.1 SFQ52756.1 mutS2 mutS2 SFQ52880.1 SFQ52880.1 SFQ52976.1 SFQ52976.1 SFQ53323.1 SFQ53323.1 SFQ53792.1 SFQ53792.1 aspS aspS SFQ57351.1 SFQ57351.1 nfi nfi rny rny pheT pheT SFQ58451.1 SFQ58451.1 dnaX dnaX SFQ60156.1 SFQ60156.1 SFQ60505.1 SFQ60505.1 SFQ60625.1 SFQ60625.1 SFQ60688.1 SFQ60688.1 metG metG pth pth tgt tgt rsmG rsmG rnc rnc SFQ61889.1 SFQ61889.1 SFQ64788.1 SFQ64788.1 SFQ65074.1 SFQ65074.1 rpoB rpoB rpoC rpoC rpoA rpoA SFQ66051.1 SFQ66051.1 SFQ66390.1 SFQ66390.1 rlmF rlmF SFQ67089.1 SFQ67089.1 SFQ72411.1 SFQ72411.1 ung ung truB truB SFQ73041.1 SFQ73041.1 priA priA queA queA dtd dtd gatC gatC rnhB rnhB SFQ74357.1 SFQ74357.1 trmD trmD queA-2 queA-2 asnS asnS proS proS SFQ76705.1 SFQ76705.1 hemA hemA SFQ77642.1 SFQ77642.1 SFQ78763.1 SFQ78763.1 SFQ78889.1 SFQ78889.1 SFQ79478.1 SFQ79478.1 SFQ79487.1 SFQ79487.1 SFQ79565.1 SFQ79565.1 SFQ79615.1 SFQ79615.1 SFQ79681.1 SFQ79681.1 SFQ79711.1 SFQ79711.1 SFQ79716.1 SFQ79716.1 SFQ79750.1 SFQ79750.1 SFQ79756.1 SFQ79756.1 SFQ79982.1 SFQ79982.1 SFQ79990.1 SFQ79990.1 SFQ80018.1 SFQ80018.1 SFQ80149.1 SFQ80149.1 SFQ80176.1 SFQ80176.1 SFQ80188.1 SFQ80188.1 SFQ81291.1 SFQ81291.1 SFQ81341.1 SFQ81341.1 SFQ81358.1 SFQ81358.1 SFQ81388.1 SFQ81388.1 SFQ82063.1 SFQ82063.1 SFQ82114.1 SFQ82114.1 SFQ82375.1 SFQ82375.1 SFQ82394.1 SFQ82394.1 SFQ82634.1 SFQ82634.1 SFQ83012.1 SFQ83012.1 SFQ83016.1 SFQ83016.1 SFQ83115.1 SFQ83115.1 SFQ83160.1 SFQ83160.1 SFQ83361.1 SFQ83361.1 SFQ83675.1 SFQ83675.1 SFQ83779.1 SFQ83779.1 SFQ84195.1 SFQ84195.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
SFQ68636.1DNA helicase-2 / ATP-dependent DNA helicase PcrA. (681 aa)
SFQ69033.1Endonuclease-3. (259 aa)
SFQ69200.1DNA polymerase III, alpha subunit. (1237 aa)
SFQ69318.1DNA polymerase (family 10). (578 aa)
SFQ69357.1seryl-tRNA synthetase. (424 aa)
rhoTranscription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. (772 aa)
SFQ71977.1Uncharacterized conserved protein, LabA/DUF88 family. (357 aa)
argSarginyl-tRNA synthetase. (598 aa)
SFP68909.1Superfamily II DNA and RNA helicase; Belongs to the DEAD box helicase family. (586 aa)
SFP69097.1tryptophanyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (324 aa)
rnzRibonuclease Z; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA; Belongs to the RNase Z family. (303 aa)
ruvCHolliday junction endonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. (213 aa)
SFP69961.1Lysylphosphatidylglycerol synthase TM region. (319 aa)
SFP70509.1TatD DNase family protein. (255 aa)
SFP72223.1DNA-3-methyladenine glycosylase II. (210 aa)
SFP72609.1UvrD-like helicase C-terminal domain-containing protein. (476 aa)
SFP72930.1tRNA-binding protein. (114 aa)
SFP75122.1DNA topoisomerase-3. (855 aa)
SFP75781.1PD-(D/E)XK nuclease superfamily protein. (997 aa)
SFP75862.1Uncharacterized conserved protein, contains HEPN domain. (116 aa)
SFP76613.1DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] (374 aa)
hisShistidyl-tRNA synthetase. (482 aa)
SFP79303.1Hypothetical protein. (406 aa)
SFP79541.1Type II restriction/modification system, DNA methylase subunit YeeA. (1031 aa)
SFP79569.1Hypothetical protein. (116 aa)
gyrBDNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (664 aa)
topADNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] (827 aa)
SFP80271.1DNA helicase-2 / ATP-dependent DNA helicase PcrA. (731 aa)
SFP80892.1tRNA1Val (adenine37-N6)-methyltransferase; Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC). (246 aa)
SFP80910.1RNase HI; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (156 aa)
xerCIntegrase/recombinase XerD; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. (299 aa)
valSvalyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. (876 aa)
rsmADimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. (277 aa)
ligADNA ligase (NAD+); DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. (701 aa)
SFP85347.123S rRNA pseudouridine2457 synthase; Belongs to the pseudouridine synthase RsuA family. (194 aa)
SFP87041.1DNA topoisomerase-1. (369 aa)
SFP87344.1DNA helicase, putative. (662 aa)
SFP87485.1AAA domain-containing protein. (1204 aa)
alaSalanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (894 aa)
gatBaspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily. (485 aa)
SFP88293.1RNA methyltransferase, TrmH family. (252 aa)
SFP89865.1Uncharacterized protein. (215 aa)
gyrADNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (866 aa)
trmBtRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. (221 aa)
SFP90733.1DNA polymerase III, delta subunit. (395 aa)
tyrStyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily. (428 aa)
thrSthreonyl-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). (644 aa)
SFP91342.1Topoisomerase-4 subunit A. (1003 aa)
SFP91404.1Topoisomerase-4 subunit B. (647 aa)
SFP91479.1DNA polymerase-3 subunit epsilon. (494 aa)
SFP91707.1Helix-turn-helix domain-containing protein. (140 aa)
dnaGDNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (698 aa)
leuSleucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (989 aa)
SFP93263.1tRNA-(ms[2]io[6]A)-hydroxylase. (198 aa)
SFP96063.1ATP-dependent RNA helicase RhlE; Belongs to the DEAD box helicase family. (499 aa)
SFP96751.1ATP-dependent RNA helicase DeaD; Belongs to the DEAD box helicase family. (677 aa)
SFP96841.1ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains). (1146 aa)
SFP97053.1Deoxyribodipyrimidine photo-lyase; Belongs to the DNA photolyase family. (441 aa)
rsmH16S rRNA (cytosine1402-N4)-methyltransferase; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. (307 aa)
SFQ01449.1Putative ATPase. (442 aa)
SFQ01749.1PIN domain-containing protein. (142 aa)
SFQ01850.1Ribosomal large subunit pseudouridine synthase E; Belongs to the pseudouridine synthase RsuA family. (224 aa)
SFQ03249.123S rRNA m(5)U-1939 methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (470 aa)
fmtmethionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. (305 aa)
dinBDNA polymerase-4; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. (359 aa)
SFQ18940.1DNA polymerase-3 subunit delta'. (381 aa)
ruvBHolliday junction DNA helicase subunit RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (352 aa)
SFQ19835.1ATP-dependent helicase HrpB. (855 aa)
recARecombination protein RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. (371 aa)
SFQ20361.123S rRNA pseudouridine955/2504/2580 synthase. (237 aa)
pheSphenylalanyl-tRNA synthetase, alpha subunit; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. (349 aa)
rlmN23S rRNA m(2)A-2503 methyltransferase; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. RlmN family. (360 aa)
SFQ22299.1Hypothetical protein. (403 aa)
uvrBExcinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] (680 aa)
SFQ23863.1DNA-3-methyladenine glycosylase; Belongs to the DNA glycosylase MPG family. (205 aa)
SFQ23933.1Lamin Tail Domain. (856 aa)
SFQ24196.1Deoxyribodipyrimidine photo-lyase (single-stranded DNA-specific); Belongs to the DNA photolyase family. (437 aa)
SFQ24697.1Hypothetical protein. (361 aa)
cysScysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (494 aa)
SFQ25187.1TIGR00255 family protein. (299 aa)
SFQ25293.1Cell surface protein SprA. (2464 aa)
ruvAHolliday junction DNA helicase subunit RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. (201 aa)
gatAaspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit A; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). (475 aa)
rsmI16S rRNA (cytidine1402-2'-O)-methyltransferase; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. (251 aa)
radADNA repair protein RadA/Sms; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. (465 aa)
SFQ27559.1Hypothetical protein. (204 aa)
SFQ27577.1Transposase. (265 aa)
polADNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. (963 aa)
SFQ28861.1Exodeoxyribonuclease-3. (264 aa)
ybeYrRNA maturation RNase YbeY; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. (165 aa)
glyQSglycyl-tRNA synthetase; Catalyzes the attachment of glycine to tRNA(Gly). Belongs to the class-II aminoacyl-tRNA synthetase family. (500 aa)
ileSIsoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. (1134 aa)
rnrRNAse R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. (825 aa)
SFQ29568.123S rRNA pseudouridine2605 synthase; Belongs to the pseudouridine synthase RsuA family. (668 aa)
gltXglutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (515 aa)
SFQ30903.1Hypothetical protein; Manually curated. (341 aa)
truAtRNA pseudouridine38-40 synthase; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. (251 aa)
SFQ31707.1Hypothetical protein. (152 aa)
SFQ31743.1Hypothetical protein. (572 aa)
uvrCExcinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. (611 aa)
SFQ34071.15-methylcytosine-specific restriction enzyme subunit McrC. (345 aa)
SFQ35706.1REP element-mobilizing transposase RayT. (176 aa)
SFQ37354.1ATP-dependent DNA helicase RecQ. (734 aa)
SFQ37438.123S rRNA (guanosine2251-2'-O)-methyltransferase; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. (349 aa)
mfdTranscription-repair coupling factor (superfamily II helicase); Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. (1137 aa)
SFQ39004.1'Cold-shock' DNA-binding domain-containing protein. (336 aa)
SFQ39145.1SpoU rRNA Methylase family protein. (172 aa)
mutSDNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. (937 aa)
SFQ39271.1tRNA 2-selenouridine synthase. (343 aa)
SFQ39506.1Ribosomal large subunit pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. (351 aa)
recGATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. (698 aa)
SFQ40124.1A/G-specific DNA-adenine glycosylase; Adenine glycosylase active on G-A mispairs. (360 aa)
SFQ40203.1Ribonuclease G. (530 aa)
nthDNA-(apurinic or apyrimidinic site) lyase; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (225 aa)
SFQ41890.1ATP-dependent RNA helicase RhlE; Belongs to the DEAD box helicase family. (470 aa)
rnpARibonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. (139 aa)
SFQ46867.1Formyl transferase. (255 aa)
mutLDNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. (685 aa)
SFQ47591.1RNA polymerase Rpb6; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. (115 aa)
lysSlysyl-tRNA synthetase, class II; Belongs to the class-II aminoacyl-tRNA synthetase family. (519 aa)
SFQ48590.1Helicase conserved C-terminal domain-containing protein. (941 aa)
SFQ48816.1PLD-like domain-containing protein. (940 aa)
SFQ49008.1Transposase. (100 aa)
SFQ49285.1Hypothetical protein. (172 aa)
SFQ49466.1Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. (460 aa)
SFQ49519.1DNA-3-methyladenine glycosylase I. (206 aa)
xseBExodeoxyribonuclease VII small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. (103 aa)
SFQ50085.1Exodeoxyribonuclease VII large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. (456 aa)
SFQ50699.1tRNA-splicing ligase RtcB. (466 aa)
SFQ50722.1tRNA-splicing ligase RtcB. (466 aa)
SFQ50828.1DNA-(apurinic or apyrimidinic site) lyase. (279 aa)
SFQ51052.1Primary replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. (537 aa)
miaAtRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. (304 aa)
SFQ51324.1Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit. (558 aa)
SFQ52610.1Site-specific DNA recombinase. (236 aa)
SFQ52756.1TIGR02757 family protein. (274 aa)
mutS2DNA mismatch repair protein MutS2; Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity; Belongs to the DNA mismatch repair MutS family. MutS2 subfamily. (814 aa)
SFQ52880.1ATP-dependent DNA helicase RecQ. (908 aa)
SFQ52976.1ATP-independent RNA helicase DbpA; Belongs to the DEAD box helicase family. (482 aa)
SFQ53323.1MutS domain V. (533 aa)
SFQ53792.1ATP-dependent DNA helicase RecQ. (645 aa)
aspSaspartyl-tRNA synthetase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. (587 aa)
SFQ57351.1glutamyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (298 aa)
nfiEndonuclease V; DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. (229 aa)
rnyRibonucrease Y; Endoribonuclease that initiates mRNA decay. (562 aa)
pheTphenylalanyl-tRNA synthetase beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. (811 aa)
SFQ58451.1Hypothetical protein. (219 aa)
dnaXDNA polymerase-3 subunit gamma/tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (685 aa)
SFQ60156.1Probable DNA metabolism protein. (306 aa)
SFQ60505.1REP element-mobilizing transposase RayT. (185 aa)
SFQ60625.1Endonuclease-3. (268 aa)
SFQ60688.1RNA methyltransferase, TrmH family. (275 aa)
metGmethionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (680 aa)
pthpeptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. (188 aa)
tgttRNA-guanine transglycosylase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the [...] (428 aa)
rsmG16S rRNA m(7)G-527 methyltransferase; Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family. (205 aa)
rncRibonuclease-3; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. (261 aa)
SFQ61889.1Amidase. (549 aa)
SFQ64788.1Hypothetical protein. (225 aa)
SFQ65074.1Amidase; Belongs to the amidase family. (498 aa)
rpoBDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1299 aa)
rpoCDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1451 aa)
rpoADNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (329 aa)
SFQ66051.123S rRNA (cytosine1962-C5)-methyltransferase. (294 aa)
SFQ66390.1Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit. (533 aa)
rlmF23S rRNA m(6)A-1618 methyltransferase; Specifically methylates the adenine in position 1618 of 23S rRNA. (324 aa)
SFQ67089.1Ribosomal large subunit pseudouridine synthase F; Belongs to the pseudouridine synthase RsuA family. (338 aa)
SFQ72411.1Hypothetical protein. (181 aa)
ungUracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. (220 aa)
truBtRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. (281 aa)
SFQ73041.1DNA polymerase-3 subunit epsilon. (203 aa)
priAReplication restart DNA helicase PriA; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (847 aa)
queAS-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). (426 aa)
dtdD-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family. (148 aa)
gatCaspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family. (95 aa)
rnhBRNase HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (196 aa)
SFQ74357.123S rRNA pseudouridine1911/1915/1917 synthase. (236 aa)
trmDtRNA (Guanine37-N(1)-) methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family. (224 aa)
queA-2S-adenosylmethionine--tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). (351 aa)
asnSasparaginyl-tRNA synthetase. (464 aa)
proSprolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). (491 aa)
SFQ76705.1Putative TIM-barrel protein, nifR3 family; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. (330 aa)
hemAglutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (423 aa)
SFQ77642.1HD domain-containing protein. (206 aa)
SFQ78763.1Protein of unknown function. (368 aa)
SFQ78889.1Transposase. (511 aa)
SFQ79478.1Recombinase. (227 aa)
SFQ79487.1Site-specific DNA recombinase. (234 aa)
SFQ79565.1Transposase. (170 aa)
SFQ79615.1Transposase. (45 aa)
SFQ79681.1Transposase. (100 aa)
SFQ79711.1Helix-turn-helix domain-containing protein. (169 aa)
SFQ79716.1Initiator Replication protein. (404 aa)
SFQ79750.1Relaxase/Mobilisation nuclease domain-containing protein. (872 aa)
SFQ79756.1Transposase. (123 aa)
SFQ79982.1Hypothetical protein. (473 aa)
SFQ79990.1Hypothetical protein. (1107 aa)
SFQ80018.1Superfamily I DNA and RNA helicases. (706 aa)
SFQ80149.1CRISPR-associated protein Csh2. (331 aa)
SFQ80176.1Transposase. (100 aa)
SFQ80188.1Transposase. (112 aa)
SFQ81291.1Transposase. (243 aa)
SFQ81341.1Transposase. (100 aa)
SFQ81358.1Transposase. (558 aa)
SFQ81388.1Initiator Replication protein. (309 aa)
SFQ82063.1Protein involved in initiation of plasmid replication. (429 aa)
SFQ82114.1Hypothetical protein. (158 aa)
SFQ82375.1Transposase. (329 aa)
SFQ82394.1Transposase. (100 aa)
SFQ82634.1Transposase. (516 aa)
SFQ83012.1Transposase; Manually curated. (251 aa)
SFQ83016.1Site-specific DNA recombinase. (222 aa)
SFQ83115.1Relaxase/Mobilisation nuclease domain-containing protein. (756 aa)
SFQ83160.1Initiator Replication protein. (345 aa)
SFQ83361.1Site-specific DNA recombinase. (204 aa)
SFQ83675.1Hypothetical protein. (67 aa)
SFQ83779.1Transcriptional regulator, LacI family. (393 aa)
SFQ84195.1Initiator Replication protein. (324 aa)
Your Current Organism:
Siccationidurans arizonensis
NCBI taxonomy Id: 1227077
Other names: DSM 17870, Hymenobacter arizonensis, Hymenobacter arizonensis Reddy and Garcia-Pichel 2013, Hymenobacter sp. OR362-8, JCM 13504, S. arizonensis, strain OR362-8
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