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C494_00175 C494_00175 C494_00277 C494_00277 C494_00877 C494_00877 C494_00902 C494_00902 C494_01252 C494_01252 C494_02646 C494_02646 PdhA PdhA C494_03025 C494_03025 C494_03090 C494_03090 C494_03095 C494_03095 Icd Icd C494_06240 C494_06240 lipA lipA PdhA-2 PdhA-2 C494_06575 C494_06575 C494_06580 C494_06580 LpdA LpdA AcnA AcnA C494_07945 C494_07945 C494_09660 C494_09660 gabD2 gabD2 C494_09950 C494_09950 C494_10370 C494_10370 C494_12060 C494_12060 C494_12445 C494_12445 SdhC SdhC C494_12490 C494_12490 C494_12495 C494_12495 C494_12500 C494_12500 C494_13996 C494_13996 C494_14333 C494_14333 C494_14363 C494_14363 fumC fumC sucD sucD sucC sucC C494_17728 C494_17728
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
C494_00175COG0281 Malic enzyme. (751 aa)
C494_00277COG2352 Phosphoenolpyruvate carboxylase. (896 aa)
C494_00877Dehydrogenase E1 component; COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit. (347 aa)
C494_00902Dihydrolipoamide S-acyltransferase; COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes. (589 aa)
C494_01252COG1866 Phosphoenolpyruvate carboxykinase (ATP). (505 aa)
C494_02646COG0095 Lipoate-protein ligase A. (278 aa)
PdhACOG1071 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit. (384 aa)
C494_030252-methylcitrate synthase/citrate synthase II; COG0372 Citrate synthase. (382 aa)
C494_03090Transketolase; COG0022 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit. (337 aa)
C494_03095COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit. (351 aa)
IcdCOG0538 Isocitrate dehydrogenases. (420 aa)
C494_06240COG0039 Malate/lactate dehydrogenases; Belongs to the LDH/MDH superfamily. (304 aa)
lipALipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (309 aa)
PdhA-2COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit. (368 aa)
C494_06575Transketolase; COG0022 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit. (332 aa)
C494_06580Branched-chain alpha-keto acid dehydrogenase subunit E2; COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes. (540 aa)
LpdACOG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes. (478 aa)
AcnAAconitate hydratase; COG1048 Aconitase A. (911 aa)
C494_07945FAD linked oxidase; COG0277 FAD/FMN-containing dehydrogenases. (476 aa)
C494_09660Male sterility domain-containing protein; COG3320 Putative dehydrogenase domain of multifunctional non-ribosomal peptide synthetases and related enzymes. (368 aa)
gabD2Succinic semialdehyde dehydrogenase; COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family. (536 aa)
C494_09950Aconitate hydratase; COG1048 Aconitase A. (656 aa)
C494_10370Catalytic domain of components of various dehydrogenase complexes; COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes. (269 aa)
C494_12060Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (775 aa)
C494_12445COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit. (639 aa)
SdhCCOG2009 Succinate dehydrogenase/fumarate reductase, cytochrome b subunit. (131 aa)
C494_12490Succinate dehydrogenase subunit D. (121 aa)
C494_12495COG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit. (292 aa)
C494_12500COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit. (612 aa)
C494_13996HpcH/HpaI aldolase; COG2301 Citrate lyase beta subunit. (436 aa)
C494_14333COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes. (453 aa)
C494_14363COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (485 aa)
fumCFumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (472 aa)
sucDsuccinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (290 aa)
sucCsuccinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (383 aa)
C494_17728Malate dehydrogenase; COG0281 Malic enzyme. (750 aa)
Your Current Organism:
Natronorubrum bangense
NCBI taxonomy Id: 1227500
Other names: N. bangense JCM 10635, Natronorubrum bangense JCM 10635
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