(12 nodes) Mixed, incl. RNA helicase activity, and RNA-binding domain, S1 network (Hymenobacter swuensis)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Predicted Interactions

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Your Input:
	nnrD	Hypothetical protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epi [...] (507 aa)
	Hsw_0389	Ribonuclease, Rne/Rng family; COG1530. (535 aa)
	Hsw_0441	DEAD/DEAH box helicase; COG0513; Belongs to the DEAD box helicase family. (476 aa)
	Hsw_1838	ATP-dependent RNA helicase DbpA; COG0513; Belongs to the DEAD box helicase family. (464 aa)
	pnp	Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. (719 aa)
	Hsw_2453	ADP-ribose diphosphatase; COG1051. (173 aa)
	Hsw_2454	DEAD/DEAH box helicase; COG0513; Belongs to the DEAD box helicase family. (485 aa)
	Hsw_2487	Cold-shock DEAD-box protein A; COG0513; Belongs to the DEAD box helicase family. (637 aa)
	Hsw_2488	Cold-shock DNA-binding domain-containing protein; COG1278. (63 aa)
	Hsw_2489	Hypothetical protein; COG0824. (138 aa)
	Hsw_2988	DEAD/DEAH box helicase; COG0513; Belongs to the DEAD box helicase family. (576 aa)
	Hsw_3155	Pyrophosphohydrolase related protein; COG0494. (190 aa)

Your Current Organism:

Hymenobacter swuensis

NCBI taxonomy Id: 1227739
Other names: H. swuensis DY53, Hymenobacter sp. DY53, Hymenobacter swuensis DY53

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Hsw_0389	Hsw_0441	Hsw_0389	Hsw_0441	Ribonuclease, Rne/Rng family; COG1530.	DEAD/DEAH box helicase; COG0513; Belongs to the DEAD box helicase family.	0.404
Hsw_0389	Hsw_1838	Hsw_0389	Hsw_1838	Ribonuclease, Rne/Rng family; COG1530.	ATP-dependent RNA helicase DbpA; COG0513; Belongs to the DEAD box helicase family.	0.404
Hsw_0389	Hsw_2454	Hsw_0389	Hsw_2454	Ribonuclease, Rne/Rng family; COG1530.	DEAD/DEAH box helicase; COG0513; Belongs to the DEAD box helicase family.	0.404
Hsw_0389	Hsw_2487	Hsw_0389	Hsw_2487	Ribonuclease, Rne/Rng family; COG1530.	Cold-shock DEAD-box protein A; COG0513; Belongs to the DEAD box helicase family.	0.404
Hsw_0389	Hsw_2988	Hsw_0389	Hsw_2988	Ribonuclease, Rne/Rng family; COG1530.	DEAD/DEAH box helicase; COG0513; Belongs to the DEAD box helicase family.	0.404
Hsw_0389	pnp	Hsw_0389	Hsw_2122	Ribonuclease, Rne/Rng family; COG1530.	Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.	0.945
Hsw_0441	Hsw_0389	Hsw_0441	Hsw_0389	DEAD/DEAH box helicase; COG0513; Belongs to the DEAD box helicase family.	Ribonuclease, Rne/Rng family; COG1530.	0.404
Hsw_0441	Hsw_2454	Hsw_0441	Hsw_2454	DEAD/DEAH box helicase; COG0513; Belongs to the DEAD box helicase family.	DEAD/DEAH box helicase; COG0513; Belongs to the DEAD box helicase family.	0.911
Hsw_0441	Hsw_2988	Hsw_0441	Hsw_2988	DEAD/DEAH box helicase; COG0513; Belongs to the DEAD box helicase family.	DEAD/DEAH box helicase; COG0513; Belongs to the DEAD box helicase family.	0.916
Hsw_0441	nnrD	Hsw_0441	Hsw_0294	DEAD/DEAH box helicase; COG0513; Belongs to the DEAD box helicase family.	Hypothetical protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epi [...]	0.643
Hsw_0441	pnp	Hsw_0441	Hsw_2122	DEAD/DEAH box helicase; COG0513; Belongs to the DEAD box helicase family.	Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.	0.706
Hsw_1838	Hsw_0389	Hsw_1838	Hsw_0389	ATP-dependent RNA helicase DbpA; COG0513; Belongs to the DEAD box helicase family.	Ribonuclease, Rne/Rng family; COG1530.	0.404
Hsw_1838	nnrD	Hsw_1838	Hsw_0294	ATP-dependent RNA helicase DbpA; COG0513; Belongs to the DEAD box helicase family.	Hypothetical protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epi [...]	0.643
Hsw_1838	pnp	Hsw_1838	Hsw_2122	ATP-dependent RNA helicase DbpA; COG0513; Belongs to the DEAD box helicase family.	Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.	0.706
Hsw_2453	Hsw_2454	Hsw_2453	Hsw_2454	ADP-ribose diphosphatase; COG1051.	DEAD/DEAH box helicase; COG0513; Belongs to the DEAD box helicase family.	0.673
Hsw_2453	nnrD	Hsw_2453	Hsw_0294	ADP-ribose diphosphatase; COG1051.	Hypothetical protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epi [...]	0.796
Hsw_2454	Hsw_0389	Hsw_2454	Hsw_0389	DEAD/DEAH box helicase; COG0513; Belongs to the DEAD box helicase family.	Ribonuclease, Rne/Rng family; COG1530.	0.404
Hsw_2454	Hsw_0441	Hsw_2454	Hsw_0441	DEAD/DEAH box helicase; COG0513; Belongs to the DEAD box helicase family.	DEAD/DEAH box helicase; COG0513; Belongs to the DEAD box helicase family.	0.911
Hsw_2454	Hsw_2453	Hsw_2454	Hsw_2453	DEAD/DEAH box helicase; COG0513; Belongs to the DEAD box helicase family.	ADP-ribose diphosphatase; COG1051.	0.673
Hsw_2454	Hsw_2988	Hsw_2454	Hsw_2988	DEAD/DEAH box helicase; COG0513; Belongs to the DEAD box helicase family.	DEAD/DEAH box helicase; COG0513; Belongs to the DEAD box helicase family.	0.912