(45 nodes) Valine, leucine and isoleucine degradation network (gamma proteobacterium L18)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	crt_2	Short-chain-enoyl-CoA hydratase. (270 aa)
	ykfA	Putative murein peptide carboxypeptidase. (312 aa)
	GCA_000497835_04545	Hypothetical protein. (120 aa)
	gabD_2	Succinate-semialdehyde dehydrogenase [NADP(+)]. (496 aa)
	fadA_3	3-ketoacyl-CoA thiolase. (397 aa)
	dpgD_2	Enoyl-CoA-hydratase. (267 aa)
	pcaI	3-oxoadipate CoA-transferase subunit A. (231 aa)
	pcaJ	3-oxoadipate CoA-transferase subunit B. (212 aa)
	GCA_000497835_04108	Hypothetical protein. (113 aa)
	calB_2	Coniferyl aldehyde dehydrogenase. (480 aa)
	fadI	3-ketoacyl-CoA thiolase. (425 aa)
	bauC_2	Putative 3-oxopropanoate dehydrogenase. (497 aa)
	bauC_1	Putative 3-oxopropanoate dehydrogenase. (499 aa)
	bbsG	(R)-benzylsuccinyl-CoA dehydrogenase. (409 aa)
	liuE	3-hydroxy-3-isohexenylglutaryl-CoA/hydroxy- methylglutaryl-CoA lyase. (306 aa)
	echA8_3	Putative enoyl-CoA hydratase echA8. (257 aa)
	mmgC_3	Acyl-CoA dehydrogenase. (375 aa)
	thlA	Acetyl-CoA acetyltransferase. (395 aa)
	ldh	Leucine dehydrogenase. (339 aa)
	GCA_000497835_02219	Hypothetical protein. (99 aa)
	GCA_000497835_00179	Hypothetical protein. (297 aa)
	pcaF	Beta-ketoadipyl-CoA thiolase. (400 aa)
	crt_1	Short-chain-enoyl-CoA hydratase. (370 aa)
	fadA_1	3-ketoacyl-CoA thiolase. (393 aa)
	fadB_1	Putative enoyl-CoA hydratase. (229 aa)
	caiD	Carnitinyl-CoA dehydratase. (263 aa)
	paaJ	3-oxoadipyl-CoA/3-oxo-5,6-dehydrosuberyl-CoA thiolase. (401 aa)
	paaF	2,3-dehydroadipyl-CoA hydratase. (256 aa)
	ilvE	Branched-chain-amino-acid aminotransferase. (339 aa)
	phaA	Acetyl-CoA acetyltransferase. (393 aa)
	GCA_000497835_01054	Hypothetical protein. (194 aa)
	GCA_000497835_01243	Hypothetical protein. (233 aa)
	bktB	Beta-ketothiolase BktB. (393 aa)
	echA8_2	Putative enoyl-CoA hydratase echA8. (362 aa)
	mmgC_2	Acyl-CoA dehydrogenase. (387 aa)
	GCA_000497835_01660	Methylmalonyl-CoA carboxyltransferase 12S subunit. (535 aa)
	dpgD_1	Enoyl-CoA-hydratase. (268 aa)
	accA1	Acetyl-/propionyl-coenzyme A carboxylase alpha chain. (623 aa)
	fadA_2	3-ketoacyl-CoA thiolase. (391 aa)
	lpdG	Dihydrolipoyl dehydrogenase. (478 aa)
	scoB	Putative succinyl-CoA:3-ketoacid coenzyme A transferase subunit B. (218 aa)
	scoA	Putative succinyl-CoA:3-ketoacid coenzyme A transferase subunit A. (232 aa)
	mmsA	Methylmalonate-semialdehyde dehydrogenase [acylating]. (515 aa)
	mmsB	3-hydroxyisobutyrate dehydrogenase. (295 aa)
	GCA_000497835_05916	Hypothetical protein. (114 aa)

Your Current Organism:

gamma proteobacterium L18

NCBI taxonomy Id: 1229486
Other names: g. proteobacterium L18

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GCA_000497835_00179	GCA_000497835_01660	GCA_000497835_00179	GCA_000497835_01660	Hypothetical protein.	Methylmalonyl-CoA carboxyltransferase 12S subunit.	0.550
GCA_000497835_00179	bktB	GCA_000497835_00179	GCA_000497835_01379	Hypothetical protein.	Beta-ketothiolase BktB.	0.499
GCA_000497835_00179	caiD	GCA_000497835_00179	GCA_000497835_00790	Hypothetical protein.	Carnitinyl-CoA dehydratase.	0.471
GCA_000497835_00179	crt_1	GCA_000497835_00179	GCA_000497835_00259	Hypothetical protein.	Short-chain-enoyl-CoA hydratase.	0.471
GCA_000497835_00179	crt_2	GCA_000497835_00179	GCA_000497835_02867	Hypothetical protein.	Short-chain-enoyl-CoA hydratase.	0.537
GCA_000497835_00179	dpgD_1	GCA_000497835_00179	GCA_000497835_01661	Hypothetical protein.	Enoyl-CoA-hydratase.	0.471
GCA_000497835_00179	dpgD_2	GCA_000497835_00179	GCA_000497835_04386	Hypothetical protein.	Enoyl-CoA-hydratase.	0.471
GCA_000497835_00179	echA8_2	GCA_000497835_00179	GCA_000497835_01658	Hypothetical protein.	Putative enoyl-CoA hydratase echA8.	0.471
GCA_000497835_00179	echA8_3	GCA_000497835_00179	GCA_000497835_03111	Hypothetical protein.	Putative enoyl-CoA hydratase echA8.	0.724
GCA_000497835_00179	fadA_1	GCA_000497835_00179	GCA_000497835_00677	Hypothetical protein.	3-ketoacyl-CoA thiolase.	0.499
GCA_000497835_00179	fadA_2	GCA_000497835_00179	GCA_000497835_01939	Hypothetical protein.	3-ketoacyl-CoA thiolase.	0.739
GCA_000497835_00179	fadA_3	GCA_000497835_00179	GCA_000497835_04394	Hypothetical protein.	3-ketoacyl-CoA thiolase.	0.739
GCA_000497835_00179	fadB_1	GCA_000497835_00179	GCA_000497835_00768	Hypothetical protein.	Putative enoyl-CoA hydratase.	0.667
GCA_000497835_00179	fadI	GCA_000497835_00179	GCA_000497835_03263	Hypothetical protein.	3-ketoacyl-CoA thiolase.	0.499
GCA_000497835_00179	paaF	GCA_000497835_00179	GCA_000497835_00965	Hypothetical protein.	2,3-dehydroadipyl-CoA hydratase.	0.724
GCA_000497835_00179	paaJ	GCA_000497835_00179	GCA_000497835_00962	Hypothetical protein.	3-oxoadipyl-CoA/3-oxo-5,6-dehydrosuberyl-CoA thiolase.	0.499
GCA_000497835_00179	pcaF	GCA_000497835_00179	GCA_000497835_00213	Hypothetical protein.	Beta-ketoadipyl-CoA thiolase.	0.499
GCA_000497835_00179	phaA	GCA_000497835_00179	GCA_000497835_01041	Hypothetical protein.	Acetyl-CoA acetyltransferase.	0.499
GCA_000497835_00179	thlA	GCA_000497835_00179	GCA_000497835_03109	Hypothetical protein.	Acetyl-CoA acetyltransferase.	0.739
GCA_000497835_01054	GCA_000497835_01660	GCA_000497835_01054	GCA_000497835_01660	Hypothetical protein.	Methylmalonyl-CoA carboxyltransferase 12S subunit.	0.505