(53 nodes) Mixed, incl. Amino acids regulate mTORC1, and Energy dependent regulation of mTOR by LKB1-AMPK network (Pestalotiopsis fici)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PFICI_14579	WD_REPEATS_REGION domain-containing protein. (436 aa)
	PFICI_14631	HRDC domain-containing protein. (810 aa)
	PFICI_14824	ANK_REP_REGION domain-containing protein. (301 aa)
	PFICI_14166	Uncharacterized protein. (537 aa)
	PFICI_14384	Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2436 aa)
	PFICI_13137	AMPK1_CBM domain-containing protein. (527 aa)
	PFICI_13883	WD_REPEATS_REGION domain-containing protein. (1473 aa)
	PFICI_13933	C2H2-type domain-containing protein. (738 aa)
	PFICI_13399	Uncharacterized protein. (226 aa)
	PFICI_13398	Non-specific serine/threonine protein kinase. (740 aa)
	PFICI_13579	WD_REPEATS_REGION domain-containing protein. (1362 aa)
	PFICI_13723	Uncharacterized protein. (484 aa)
	PFICI_11767	Uncharacterized protein. (1122 aa)
	PFICI_11836	Uncharacterized protein. (413 aa)
	PFICI_11861	BTB domain-containing protein. (388 aa)
	PFICI_12075	Protein kinase domain-containing protein. (912 aa)
	PFICI_12092	GTP-binding protein rhb1. (187 aa)
	PFICI_12102	WAPL domain-containing protein. (865 aa)
	PFICI_13000	GTP-binding protein gtr2. (396 aa)
	PFICI_11733	Uncharacterized protein. (812 aa)
	PFICI_12074	Protein kinase domain-containing protein. (927 aa)
	PFICI_11833	BTB domain-containing protein. (419 aa)
	PFICI_09901	Uncharacterized protein. (670 aa)
	PFICI_10940	AMPKBI domain-containing protein. (489 aa)
	PFICI_10084	Uncharacterized protein. (140 aa)
	PFICI_09297	Protein kinase domain-containing protein. (1239 aa)
	PFICI_07837	Peptidase_S24 domain-containing protein. (170 aa)
	PFICI_07839	Nuclear protein SNF4. (375 aa)
	PFICI_07973	Uncharacterized protein. (508 aa)
	PFICI_08107	Protein kinase domain-containing protein. (699 aa)
	PFICI_08267	Zinc_ribbon_16 domain-containing protein. (1038 aa)
	PFICI_08438	Uncharacterized protein. (968 aa)
	PFICI_06082	Uncharacterized protein. (536 aa)
	PFICI_07840	Rho-GAP domain-containing protein. (1318 aa)
	PFICI_08091	Rap-GAP domain-containing protein. (1627 aa)
	PFICI_07290	Target of rapamycin complex subunit LST8. (435 aa)
	PFICI_06644	Uncharacterized protein. (482 aa)
	PFICI_04586	Uncharacterized protein. (994 aa)
	PFICI_04770	DEP domain-containing protein. (1867 aa)
	PFICI_05376	Non-specific serine/threonine protein kinase. (638 aa)
	PFICI_05328	Uncharacterized protein. (1326 aa)
	PFICI_03018	WD_REPEATS_REGION domain-containing protein. (1489 aa)
	PFICI_03110	NACHT domain-containing protein. (1007 aa)
	PFICI_03310	UDENN FLCN/SMCR8-type domain-containing protein. (537 aa)
	PFICI_03555	Uncharacterized protein. (478 aa)
	PFICI_03575	Uncharacterized protein. (272 aa)
	PFICI_04190	Uncharacterized protein. (357 aa)
	PFICI_00248	Uncharacterized protein. (357 aa)
	PFICI_00543	Non-specific serine/threonine protein kinase. (886 aa)
	PFICI_01101	Telomere_reg-2 domain-containing protein. (970 aa)
	PFICI_01678	Protein kinase domain-containing protein. (871 aa)
	PFICI_01892	DUF1752 domain-containing protein. (585 aa)
	PFICI_01953	Uncharacterized protein. (816 aa)

Your Current Organism:

Pestalotiopsis fici

NCBI taxonomy Id: 1229662
Other names: P. fici W106-1, Pestalotiopsis fici W106-1

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PFICI_00248	PFICI_10940	W3XK94	W3WW34	Uncharacterized protein.	AMPKBI domain-containing protein.	0.426
PFICI_00248	PFICI_13137	W3XK94	W3WLA5	Uncharacterized protein.	AMPK1_CBM domain-containing protein.	0.426
PFICI_00543	PFICI_05328	W3XL57	W3XDF9	Non-specific serine/threonine protein kinase.	Uncharacterized protein.	0.590
PFICI_00543	PFICI_07290	W3XL57	W3X851	Non-specific serine/threonine protein kinase.	Target of rapamycin complex subunit LST8.	0.947
PFICI_00543	PFICI_08091	W3XL57	W3X567	Non-specific serine/threonine protein kinase.	Rap-GAP domain-containing protein.	0.455
PFICI_00543	PFICI_11733	W3XL57	W3WU28	Non-specific serine/threonine protein kinase.	Uncharacterized protein.	0.645
PFICI_00543	PFICI_13883	W3XL57	W3WLG8	Non-specific serine/threonine protein kinase.	WD_REPEATS_REGION domain-containing protein.	0.956
PFICI_00543	PFICI_14384	W3XL57	W3WKV1	Non-specific serine/threonine protein kinase.	Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family.	0.976
PFICI_00543	PFICI_14631	W3XL57	W3WID2	Non-specific serine/threonine protein kinase.	HRDC domain-containing protein.	0.572
PFICI_01101	PFICI_05328	W3XML0	W3XDF9	Telomere_reg-2 domain-containing protein.	Uncharacterized protein.	0.704
PFICI_01101	PFICI_07290	W3XML0	W3X851	Telomere_reg-2 domain-containing protein.	Target of rapamycin complex subunit LST8.	0.696
PFICI_01101	PFICI_11733	W3XML0	W3WU28	Telomere_reg-2 domain-containing protein.	Uncharacterized protein.	0.611
PFICI_01101	PFICI_11767	W3XML0	W3WR86	Telomere_reg-2 domain-containing protein.	Uncharacterized protein.	0.991
PFICI_01101	PFICI_13000	W3XML0	W3WT99	Telomere_reg-2 domain-containing protein.	GTP-binding protein gtr2.	0.437
PFICI_01101	PFICI_13579	W3XML0	W3WMF1	Telomere_reg-2 domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.417
PFICI_01101	PFICI_13883	W3XML0	W3WLG8	Telomere_reg-2 domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.667
PFICI_01101	PFICI_14384	W3XML0	W3WKV1	Telomere_reg-2 domain-containing protein.	Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family.	0.781
PFICI_01101	PFICI_14579	W3XML0	W3WIC2	Telomere_reg-2 domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.528
PFICI_01101	PFICI_14631	W3XML0	W3WID2	Telomere_reg-2 domain-containing protein.	HRDC domain-containing protein.	0.781
PFICI_01678	PFICI_04190	W3XPG3	W3XJH0	Protein kinase domain-containing protein.	Uncharacterized protein.	0.518