(18 nodes) Translesion synthesis by POLK network (Pestalotiopsis fici)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Predicted Interactions

gene neighborhood

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Your Input:
	PFICI_11389	Amino_oxidase domain-containing protein. (517 aa)
	PFICI_11573	Uncharacterized protein. (144 aa)
	PFICI_01848	DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family. (1142 aa)
	PFICI_13385	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (617 aa)
	PFICI_01262	Uncharacterized protein. (369 aa)
	PFICI_03052	Amino_oxidase domain-containing protein. (528 aa)
	PFICI_02254	SnoaL-like domain-containing protein. (142 aa)
	PFICI_14813	Ubiquitin-40S ribosomal protein S27a. (153 aa)
	PFICI_14182	Polyubiquitin. (305 aa)
	PFICI_14302	Zds_C domain-containing protein. (897 aa)
	PFICI_05829	Amino_oxidase domain-containing protein. (504 aa)
	PFICI_05286	AAA domain-containing protein. (1209 aa)
	PFICI_06832	UmuC domain-containing protein. (660 aa)
	PFICI_06311	Uncharacterized protein. (507 aa)
	PFICI_06301	BRCT domain-containing protein. (318 aa)
	PFICI_08293	Uncharacterized protein. (148 aa)
	PFICI_07439	Uncharacterized protein. (107 aa)
	PFICI_10257	BZIP domain-containing protein. (275 aa)

Your Current Organism:

Pestalotiopsis fici

NCBI taxonomy Id: 1229662
Other names: P. fici W106-1, Pestalotiopsis fici W106-1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PFICI_01262	PFICI_13385	W3XN68	W3WQ03	Uncharacterized protein.	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.	0.516
PFICI_01848	PFICI_05286	W3XPX6	W3XBJ3	DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family.	AAA domain-containing protein.	0.468
PFICI_01848	PFICI_06832	W3XPX6	W3X703	DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family.	UmuC domain-containing protein.	0.911
PFICI_01848	PFICI_10257	W3XPX6	W3WWH0	DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family.	BZIP domain-containing protein.	0.683
PFICI_01848	PFICI_13385	W3XPX6	W3WQ03	DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family.	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.	0.542
PFICI_01848	PFICI_14182	W3XPX6	W3WNC7	DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family.	Polyubiquitin.	0.661
PFICI_01848	PFICI_14813	W3XPX6	W3WL37	DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family.	Ubiquitin-40S ribosomal protein S27a.	0.683
PFICI_02254	PFICI_13385	W3XE04	W3WQ03	SnoaL-like domain-containing protein.	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.	0.516
PFICI_03052	PFICI_13385	W3XHV9	W3WQ03	Amino_oxidase domain-containing protein.	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.	0.516
PFICI_05286	PFICI_01848	W3XBJ3	W3XPX6	AAA domain-containing protein.	DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family.	0.468
PFICI_05286	PFICI_06301	W3XBJ3	W3X5L8	AAA domain-containing protein.	BRCT domain-containing protein.	0.468
PFICI_05286	PFICI_06832	W3XBJ3	W3X703	AAA domain-containing protein.	UmuC domain-containing protein.	0.535
PFICI_05286	PFICI_13385	W3XBJ3	W3WQ03	AAA domain-containing protein.	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.	0.692
PFICI_05829	PFICI_13385	W3XCX5	W3WQ03	Amino_oxidase domain-containing protein.	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.	0.516
PFICI_06301	PFICI_05286	W3X5L8	W3XBJ3	BRCT domain-containing protein.	AAA domain-containing protein.	0.468
PFICI_06301	PFICI_06832	W3X5L8	W3X703	BRCT domain-containing protein.	UmuC domain-containing protein.	0.896
PFICI_06301	PFICI_10257	W3X5L8	W3WWH0	BRCT domain-containing protein.	BZIP domain-containing protein.	0.683
PFICI_06301	PFICI_13385	W3X5L8	W3WQ03	BRCT domain-containing protein.	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.	0.542
PFICI_06301	PFICI_14182	W3X5L8	W3WNC7	BRCT domain-containing protein.	Polyubiquitin.	0.661
PFICI_06301	PFICI_14813	W3X5L8	W3WL37	BRCT domain-containing protein.	Ubiquitin-40S ribosomal protein S27a.	0.683