(61 nodes) Butanoate metabolism network (Fusarium oxysporum f. sp. cubense race 1)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	FOC1_g10002441	DAO domain-containing protein. (407 aa)
	FOC1_g10015294	Succinate-semialdehyde dehydrogenase [NADP+] GabD. (499 aa)
	FOC1_g10009260	Acetyl-CoA acetyltransferase, mitochondrial; Belongs to the thiolase-like superfamily. Thiolase family. (430 aa)
	FOC1_g10013749	Putative 3-hydroxybutyryl-CoA dehydrogenase. (319 aa)
	FOC1_g10007918	Lambda-crystallin like protein. (320 aa)
	FOC1_g10002622	Succinate-semialdehyde dehydrogenase [NADP+]; Belongs to the aldehyde dehydrogenase family. (498 aa)
	FOC1_g10015959	Putative oxidoreductase ordL. (463 aa)
	FOC1_g10006944	15-hydroxyprostaglandin dehydrogenase [NAD+]. (305 aa)
	FOC1_g10016263	Hydroxymethylglutaryl-CoA lyase, mitochondrial. (369 aa)
	FOC1_g10016356	Salicylaldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (477 aa)
	FOC1_g10007539	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. (491 aa)
	FOC1_g10016119	Succinate-semialdehyde dehydrogenase. (527 aa)
	FOC1_g10010816	Putative oxidoreductase ordL. (464 aa)
	FOC1_g10008090	Maleylacetate reductase. (257 aa)
	FOC1_g10014403	Acetoacetyl-CoA synthetase. (644 aa)
	FOC1_g10013632	Putative enoyl-CoA hydratase, mitochondrial; Belongs to the enoyl-CoA hydratase/isomerase family. (290 aa)
	FOC1_g10010108	Phenylacetaldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (467 aa)
	FOC1_g10011945	Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (396 aa)
	FOC1_g10005787	Uncharacterized protein. (878 aa)
	FOC1_g10009475	Acetolactate synthase; Belongs to the TPP enzyme family. (429 aa)
	FOC1_g10013681	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (459 aa)
	FOC1_g10013986	Glutamate decarboxylase 2. (506 aa)
	FOC1_g10004269	Alpha-acetolactate decarboxylase. (240 aa)
	FOC1_g10002347	15-hydroxyprostaglandin dehydrogenase [NAD+]. (270 aa)
	FOC1_g10001444	Salicylaldehyde dehydrogenase. (488 aa)
	FOC1_g10003275	Succinate-semialdehyde dehydrogenase, mitochondrial. (516 aa)
	FOC1_g10003596	Uncharacterized protein. (263 aa)
	FOC1_g10013682	Succinate-semialdehyde dehydrogenase. (490 aa)
	FOC1_g10006060	Putative enoyl-CoA hydratase, mitochondrial. (281 aa)
	FOC1_g10005634	Enoyl-CoA hydratase, mitochondrial. (262 aa)
	FOC1_g10004587	Salicylaldehyde dehydrogenase. (500 aa)
	FOC1_g10013231	Glutamate decarboxylase; Belongs to the group II decarboxylase family. (578 aa)
	FOC1_g10000901	2,2-dialkylglycine decarboxylase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (423 aa)
	FOC1_g10007457	Putative diacetyl reductase [(R)-acetoin forming] 2. (359 aa)
	FOC1_g10007494	Uncharacterized protein. (354 aa)
	FOC1_g10003806	Succinate-semialdehyde dehydrogenase [NADP+]. (499 aa)
	FOC1_g10009474	Alpha-acetolactate decarboxylase. (189 aa)
	FOC1_g10005291	15-hydroxyprostaglandin dehydrogenase [NAD+]. (314 aa)
	FOC1_g10010444	Acetolactate synthase. (684 aa)
	FOC1_g10010565	Succinate-semialdehyde dehydrogenase [NADP+] GabD; Belongs to the aldehyde dehydrogenase family. (494 aa)
	FOC1_g10014104	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. (519 aa)
	FOC1_g10014169	Acetolactate synthase small subunit, mitochondrial. (312 aa)
	FOC1_g10011997	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (456 aa)
	FOC1_g10002343	Acetoacetyl-CoA synthetase. (687 aa)
	FOC1_g10014688	DAO domain-containing protein. (334 aa)
	FOC1_g10001200	Succinate-semialdehyde dehydrogenase [NADP+] GabD. (500 aa)
	FOC1_g10005457	Putative enoyl-CoA hydratase paaF; Belongs to the enoyl-CoA hydratase/isomerase family. (313 aa)
	FOC1_g10010352	L-2-hydroxyglutarate dehydrogenase, mitochondrial. (413 aa)
	FOC1_g10000458	Acetoacetyl-CoA synthetase. (669 aa)
	FOC1_g10002344	Hydroxymethylglutaryl-CoA lyase, mitochondrial. (642 aa)
	FOC1_g10001219	Glutamate decarboxylase; Belongs to the group II decarboxylase family. (509 aa)
	FOC1_g10008990	Diacetyl reductase [(R)-acetoin forming]. (355 aa)
	FOC1_g10013316	DAO domain-containing protein. (472 aa)
	FOC1_g10008736	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (502 aa)
	FOC1_g10003509	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. (582 aa)
	FOC1_g10013243	3-oxoadipate enol-lactonase 2. (534 aa)
	FOC1_g10008984	3-hydroxybutyryl-CoA dehydrogenase. (603 aa)
	FOC1_g10010466	Acetoacetyl-CoA synthetase. (696 aa)
	FOC1_g10009794	Succinate-semialdehyde dehydrogenase [NADP+] GabD; Belongs to the aldehyde dehydrogenase family. (546 aa)
	FOC1_g10003551	Lambda-crystallin like protein. (324 aa)
	FOC1_g10003228	Uncharacterized protein. (401 aa)

Your Current Organism:

Fusarium oxysporum f. sp. cubense race 1

NCBI taxonomy Id: 1229664
Other names: F. oxysporum f. sp. cubense race 1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FOC1_g10000458	FOC1_g10001200	N4ULX8	N4UJK6	Acetoacetyl-CoA synthetase.	Succinate-semialdehyde dehydrogenase [NADP+] GabD.	0.486
FOC1_g10000458	FOC1_g10001444	N4ULX8	N4U4J3	Acetoacetyl-CoA synthetase.	Salicylaldehyde dehydrogenase.	0.486
FOC1_g10000458	FOC1_g10002343	N4ULX8	N4UJ66	Acetoacetyl-CoA synthetase.	Acetoacetyl-CoA synthetase.	0.579
FOC1_g10000458	FOC1_g10002344	N4ULX8	N4UMK5	Acetoacetyl-CoA synthetase.	Hydroxymethylglutaryl-CoA lyase, mitochondrial.	0.593
FOC1_g10000458	FOC1_g10002622	N4ULX8	N4TMU3	Acetoacetyl-CoA synthetase.	Succinate-semialdehyde dehydrogenase [NADP+]; Belongs to the aldehyde dehydrogenase family.	0.486
FOC1_g10000458	FOC1_g10003228	N4ULX8	N4V190	Acetoacetyl-CoA synthetase.	Uncharacterized protein.	0.569
FOC1_g10000458	FOC1_g10003275	N4ULX8	N4U4K3	Acetoacetyl-CoA synthetase.	Succinate-semialdehyde dehydrogenase, mitochondrial.	0.486
FOC1_g10000458	FOC1_g10003509	N4ULX8	N4UTS8	Acetoacetyl-CoA synthetase.	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	0.589
FOC1_g10000458	FOC1_g10003551	N4ULX8	N4V0Z5	Acetoacetyl-CoA synthetase.	Lambda-crystallin like protein.	0.647
FOC1_g10000458	FOC1_g10003596	N4ULX8	N4U507	Acetoacetyl-CoA synthetase.	Uncharacterized protein.	0.569
FOC1_g10000458	FOC1_g10003806	N4ULX8	N4UDU8	Acetoacetyl-CoA synthetase.	Succinate-semialdehyde dehydrogenase [NADP+].	0.486
FOC1_g10000458	FOC1_g10004587	N4ULX8	N4UAU8	Acetoacetyl-CoA synthetase.	Salicylaldehyde dehydrogenase.	0.486
FOC1_g10000458	FOC1_g10005457	N4ULX8	N4UJS8	Acetoacetyl-CoA synthetase.	Putative enoyl-CoA hydratase paaF; Belongs to the enoyl-CoA hydratase/isomerase family.	0.559
FOC1_g10000458	FOC1_g10005634	N4ULX8	N4U7S7	Acetoacetyl-CoA synthetase.	Enoyl-CoA hydratase, mitochondrial.	0.559
FOC1_g10000458	FOC1_g10005787	N4ULX8	N4U1G1	Acetoacetyl-CoA synthetase.	Uncharacterized protein.	0.644
FOC1_g10000458	FOC1_g10006060	N4ULX8	N4U7S3	Acetoacetyl-CoA synthetase.	Putative enoyl-CoA hydratase, mitochondrial.	0.559
FOC1_g10000458	FOC1_g10007457	N4ULX8	N4UDC5	Acetoacetyl-CoA synthetase.	Putative diacetyl reductase [(R)-acetoin forming] 2.	0.428
FOC1_g10000458	FOC1_g10007494	N4ULX8	N4UDF9	Acetoacetyl-CoA synthetase.	Uncharacterized protein.	0.701
FOC1_g10000458	FOC1_g10007539	N4ULX8	N4TTE1	Acetoacetyl-CoA synthetase.	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	0.589
FOC1_g10000458	FOC1_g10007918	N4ULX8	N4TM72	Acetoacetyl-CoA synthetase.	Lambda-crystallin like protein.	0.647