STRINGSTRING
GRFL_0215 GRFL_0215 aroK aroK GRFL_0633 GRFL_0633 GRFL_0634 GRFL_0634 GRFL_0635 GRFL_0635 GRFL_0636 GRFL_0636 GRFL_0637 GRFL_0637 GRFL_0638 GRFL_0638 GRFL_0639 GRFL_0639 trpD trpD trpC trpC trpF trpF trpB trpB trpA trpA GRFL_0645 GRFL_0645 GRFL_0646 GRFL_0646 thiL thiL GRFL_2120 GRFL_2120 GRFL_2121 GRFL_2121 GRFL_2122 GRFL_2122 GRFL_2123 GRFL_2123 rsgA rsgA dtd dtd GRFL_2126 GRFL_2126 GRFL_2127 GRFL_2127 GRFL_2128 GRFL_2128 GRFL_2129 GRFL_2129 aroA aroA GRFL_2626 GRFL_2626 GRFL_3182 GRFL_3182 aroC aroC aroQ aroQ
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GRFL_0215Para-aminobenzoate synthase, aminase component. (432 aa)
aroKShikimate kinase I; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (173 aa)
GRFL_0633Extracellular alkaline serine protease; Belongs to the peptidase S8 family. (410 aa)
GRFL_0634Protein containing rhodanese-like domain. (103 aa)
GRFL_0635Transcriptional regulator, MarR family. (150 aa)
GRFL_0636Oxygen-insensitive NAD(P)H nitroreductase; Dihydropteridine reductase. (217 aa)
GRFL_0637Rhodanese-like domain protein; Belongs to the UPF0312 family. (189 aa)
GRFL_0638Anthranilate synthase, aminase component. (464 aa)
GRFL_0639Anthranilate synthase, amidotransferase component. (208 aa)
trpDAnthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (334 aa)
trpCIndole-3-glycerol phosphate synthase; Belongs to the TrpC family. (260 aa)
trpFPhosphoribosylanthranilate isomerase; Belongs to the TrpF family. (232 aa)
trpBTryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (393 aa)
trpATryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (256 aa)
GRFL_0645Hypothetical protein. (47 aa)
GRFL_0646Hypothetical protein. (44 aa)
thiLThiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. (350 aa)
GRFL_2120Prephenate dehydratase. (275 aa)
GRFL_2121Biosynthetic Aromatic amino acid aminotransferase alpha. (381 aa)
GRFL_2122Prephenate and/or arogenate dehydrogenase (unknown specificity). (294 aa)
GRFL_21232-keto-3-deoxy-D-arabino-heptulosonate-7- phosphate synthase I beta; Chorismate mutase I. (363 aa)
rsgARibosome small subunit-stimulated GTPase EngC; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily. (315 aa)
dtdD-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family. (150 aa)
GRFL_2126Hypothetical protein. (628 aa)
GRFL_2127Hypothetical protein. (663 aa)
GRFL_2128Hypothetical protein. (108 aa)
GRFL_2129Hypothetical protein. (84 aa)
aroA5-Enolpyruvylshikimate-3-phosphate synthase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (405 aa)
GRFL_2626Shikimate 5-dehydrogenase I alpha. (241 aa)
GRFL_31823-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (376 aa)
aroCChorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (354 aa)
aroQ3-dehydroquinate dehydratase II; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (126 aa)
Your Current Organism:
Gramella flava
NCBI taxonomy Id: 1229726
Other names: G. flava JLT2011, Gramella flava JLT2011, Gramella sp. JLT2011
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.