(14 nodes) Aromatic amino acid biosynthesis, and Anthranilate synthase component I-like network (Gramella flava)

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Your Input:
	GRFL_0215	Para-aminobenzoate synthase, aminase component. (432 aa)
	aroK	Shikimate kinase I; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (173 aa)
	GRFL_0638	Anthranilate synthase, aminase component. (464 aa)
	GRFL_0639	Anthranilate synthase, amidotransferase component. (208 aa)
	trpD	Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (334 aa)
	trpC	Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. (260 aa)
	trpF	Phosphoribosylanthranilate isomerase; Belongs to the TrpF family. (232 aa)
	trpB	Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (393 aa)
	trpA	Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (256 aa)
	aroA	5-Enolpyruvylshikimate-3-phosphate synthase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (405 aa)
	GRFL_2626	Shikimate 5-dehydrogenase I alpha. (241 aa)
	GRFL_3182	3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (376 aa)
	aroC	Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (354 aa)
	aroQ	3-dehydroquinate dehydratase II; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (126 aa)

Your Current Organism:

Gramella flava

NCBI taxonomy Id: 1229726
Other names: G. flava JLT2011, Gramella flava JLT2011, Gramella sp. JLT2011

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GRFL_0215	GRFL_0638	GRFL_0215	GRFL_0638	Para-aminobenzoate synthase, aminase component.	Anthranilate synthase, aminase component.	0.848
GRFL_0215	GRFL_0639	GRFL_0215	GRFL_0639	Para-aminobenzoate synthase, aminase component.	Anthranilate synthase, amidotransferase component.	0.999
GRFL_0215	GRFL_2626	GRFL_0215	GRFL_2626	Para-aminobenzoate synthase, aminase component.	Shikimate 5-dehydrogenase I alpha.	0.606
GRFL_0215	GRFL_3182	GRFL_0215	GRFL_3182	Para-aminobenzoate synthase, aminase component.	3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).	0.556
GRFL_0215	aroC	GRFL_0215	GRFL_3298	Para-aminobenzoate synthase, aminase component.	Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.	0.917
GRFL_0215	aroK	GRFL_0215	GRFL_0478	Para-aminobenzoate synthase, aminase component.	Shikimate kinase I; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.	0.528
GRFL_0215	trpA	GRFL_0215	GRFL_0644	Para-aminobenzoate synthase, aminase component.	Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.	0.921
GRFL_0215	trpB	GRFL_0215	GRFL_0643	Para-aminobenzoate synthase, aminase component.	Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.	0.923
GRFL_0215	trpC	GRFL_0215	GRFL_0641	Para-aminobenzoate synthase, aminase component.	Indole-3-glycerol phosphate synthase; Belongs to the TrpC family.	0.979
GRFL_0215	trpD	GRFL_0215	GRFL_0640	Para-aminobenzoate synthase, aminase component.	Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).	0.978
GRFL_0215	trpF	GRFL_0215	GRFL_0642	Para-aminobenzoate synthase, aminase component.	Phosphoribosylanthranilate isomerase; Belongs to the TrpF family.	0.879
GRFL_0638	GRFL_0215	GRFL_0638	GRFL_0215	Anthranilate synthase, aminase component.	Para-aminobenzoate synthase, aminase component.	0.848
GRFL_0638	GRFL_0639	GRFL_0638	GRFL_0639	Anthranilate synthase, aminase component.	Anthranilate synthase, amidotransferase component.	0.999
GRFL_0638	GRFL_2626	GRFL_0638	GRFL_2626	Anthranilate synthase, aminase component.	Shikimate 5-dehydrogenase I alpha.	0.499
GRFL_0638	GRFL_3182	GRFL_0638	GRFL_3182	Anthranilate synthase, aminase component.	3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).	0.562
GRFL_0638	aroC	GRFL_0638	GRFL_3298	Anthranilate synthase, aminase component.	Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.	0.953
GRFL_0638	trpA	GRFL_0638	GRFL_0644	Anthranilate synthase, aminase component.	Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.	0.973
GRFL_0638	trpB	GRFL_0638	GRFL_0643	Anthranilate synthase, aminase component.	Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.	0.979
GRFL_0638	trpC	GRFL_0638	GRFL_0641	Anthranilate synthase, aminase component.	Indole-3-glycerol phosphate synthase; Belongs to the TrpC family.	0.998
GRFL_0638	trpD	GRFL_0638	GRFL_0640	Anthranilate synthase, aminase component.	Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).	0.999