STRINGSTRING
acsA acsA purC purC GRFL_0036 GRFL_0036 proC proC proB proB proA proA GRFL_0060 GRFL_0060 thrB thrB GRFL_0062 GRFL_0062 GRFL_0063 GRFL_0063 GRFL_0102 GRFL_0102 GRFL_0103 GRFL_0103 GRFL_0120 GRFL_0120 menB menB menD menD GRFL_0141 GRFL_0141 GRFL_0142 GRFL_0142 GRFL_0149 GRFL_0149 GRFL_0151 GRFL_0151 panB panB GRFL_0159 GRFL_0159 leuC leuC leuD leuD leuB leuB argH argH GRFL_0164 GRFL_0164 argB argB GRFL_0167 GRFL_0167 proC-2 proC-2 argC argC GRFL_0170 GRFL_0170 ilvA ilvA ilvC ilvC GRFL_0174 GRFL_0174 GRFL_0175 GRFL_0175 ilvD ilvD GRFL_0190 GRFL_0190 pfkA pfkA GRFL_0201 GRFL_0201 GRFL_0211 GRFL_0211 GRFL_0226 GRFL_0226 ribB ribB GRFL_0262 GRFL_0262 GRFL_0278 GRFL_0278 GRFL_0280 GRFL_0280 GRFL_0298 GRFL_0298 GRFL_0319 GRFL_0319 GRFL_0332 GRFL_0332 GRFL_0393 GRFL_0393 miaA miaA GRFL_0419 GRFL_0419 dapA dapA GRFL_0429 GRFL_0429 GRFL_0435 GRFL_0435 dapF dapF GRFL_0448 GRFL_0448 GRFL_0453 GRFL_0453 accA accA GRFL_0471 GRFL_0471 GRFL_0472 GRFL_0472 aroK aroK GRFL_0482 GRFL_0482 GRFL_0483 GRFL_0483 GRFL_0484 GRFL_0484 GRFL_0485 GRFL_0485 GRFL_0487 GRFL_0487 guaB guaB GRFL_0501 GRFL_0501 GRFL_0509 GRFL_0509 GRFL_0528 GRFL_0528 GRFL_0585 GRFL_0585 GRFL_0638 GRFL_0638 GRFL_0639 GRFL_0639 trpD trpD trpC trpC trpF trpF trpB trpB trpA trpA GRFL_0663 GRFL_0663 psd psd GRFL_0668 GRFL_0668 GRFL_0675 GRFL_0675 GRFL_0690 GRFL_0690 GRFL_0693 GRFL_0693 mdh mdh GRFL_0718 GRFL_0718 GRFL_0766 GRFL_0766 GRFL_0767 GRFL_0767 eno eno adk adk purK purK purE purE gcvP gcvP GRFL_0834 GRFL_0834 GRFL_0838 GRFL_0838 pdhA pdhA GRFL_0863 GRFL_0863 GRFL_0927 GRFL_0927 GRFL_0957 GRFL_0957 GRFL_0958 GRFL_0958 purH purH surE surE GRFL_1008 GRFL_1008 GRFL_1070 GRFL_1070 glgB glgB GRFL_1072 GRFL_1072 GRFL_1132 GRFL_1132 GRFL_1172 GRFL_1172 GRFL_1173 GRFL_1173 GRFL_1174 GRFL_1174 GRFL_1234 GRFL_1234 GRFL_1235 GRFL_1235 GRFL_1236 GRFL_1236 pgi pgi GRFL_1289 GRFL_1289 GRFL_1294 GRFL_1294 hemH hemH hemA hemA GRFL_1301 GRFL_1301 GRFL_1302 GRFL_1302 hemE hemE GRFL_1305 GRFL_1305 GRFL_1306 GRFL_1306 GRFL_1327 GRFL_1327 GRFL_1335 GRFL_1335 purD purD GRFL_1359 GRFL_1359 GRFL_1360 GRFL_1360 GRFL_1361 GRFL_1361 pgk pgk gltX gltX GRFL_1387 GRFL_1387 GRFL_1399 GRFL_1399 GRFL_1449 GRFL_1449 GRFL_1454 GRFL_1454 GRFL_1455 GRFL_1455 asd asd GRFL_1487 GRFL_1487 purN purN acpP acpP GRFL_1495 GRFL_1495 GRFL_1506 GRFL_1506 GRFL_1508 GRFL_1508 GRFL_1538 GRFL_1538 GRFL_1552 GRFL_1552 GRFL_1570 GRFL_1570 dxs dxs GRFL_1615 GRFL_1615 GRFL_1662 GRFL_1662 GRFL_1666 GRFL_1666 GRFL_1667 GRFL_1667 GRFL_1674 GRFL_1674 GRFL_1679 GRFL_1679 fbp fbp panD panD panC panC GRFL_1705 GRFL_1705 GRFL_1773 GRFL_1773 GRFL_1792 GRFL_1792 GRFL_1793 GRFL_1793 GRFL_1795 GRFL_1795 GRFL_1816 GRFL_1816 katG katG GRFL_1857 GRFL_1857 pckA pckA GRFL_1877 GRFL_1877 GRFL_1901 GRFL_1901 GRFL_1921 GRFL_1921 GRFL_1922 GRFL_1922 GRFL_1923 GRFL_1923 GRFL_1926 GRFL_1926 GRFL_1927 GRFL_1927 gcvH gcvH ctaB ctaB GRFL_1999 GRFL_1999 hemL hemL GRFL_2031 GRFL_2031 GRFL_2061 GRFL_2061 GRFL_2080 GRFL_2080 GRFL_2095 GRFL_2095 GRFL_2097 GRFL_2097 GRFL_2098 GRFL_2098 metK metK GRFL_2103 GRFL_2103 GRFL_2108 GRFL_2108 GRFL_2109 GRFL_2109 GRFL_2114 GRFL_2114 GRFL_2115 GRFL_2115 GRFL_2120 GRFL_2120 GRFL_2121 GRFL_2121 GRFL_2122 GRFL_2122 GRFL_2123 GRFL_2123 aroA aroA GRFL_2133 GRFL_2133 GRFL_2149 GRFL_2149 fbp-2 fbp-2 GRFL_2189 GRFL_2189 GRFL_2191 GRFL_2191 accD accD GRFL_2197 GRFL_2197 menG menG GRFL_2207 GRFL_2207 gpmI gpmI tpiA tpiA GRFL_2250 GRFL_2250 GRFL_2257 GRFL_2257 GRFL_2268 GRFL_2268 tal tal GRFL_2281 GRFL_2281 GRFL_2304 GRFL_2304 GRFL_2327 GRFL_2327 GRFL_2397 GRFL_2397 GRFL_2399 GRFL_2399 GRFL_2415 GRFL_2415 GRFL_2427 GRFL_2427 GRFL_2433 GRFL_2433 GRFL_2435 GRFL_2435 GRFL_2456 GRFL_2456 mqo mqo menA menA GRFL_2504 GRFL_2504 GRFL_2506 GRFL_2506 GRFL_2526 GRFL_2526 GRFL_2542 GRFL_2542 glyA glyA tal-2 tal-2 GRFL_2560 GRFL_2560 GRFL_2574 GRFL_2574 lysA lysA sucC sucC GRFL_2615 GRFL_2615 GRFL_2621 GRFL_2621 GRFL_2626 GRFL_2626 GRFL_2630 GRFL_2630 GRFL_2637 GRFL_2637 ndk ndk ribH ribH dapB dapB GRFL_2776 GRFL_2776 GRFL_2858 GRFL_2858 GRFL_2863 GRFL_2863 GRFL_2864 GRFL_2864 GRFL_2911 GRFL_2911 GRFL_2912 GRFL_2912 GRFL_2915 GRFL_2915 GRFL_2922 GRFL_2922 GRFL_2925 GRFL_2925 GRFL_2927 GRFL_2927 purL purL GRFL_2942 GRFL_2942 GRFL_2973 GRFL_2973 GRFL_3040 GRFL_3040 GRFL_3041 GRFL_3041 GRFL_3043 GRFL_3043 GRFL_3050 GRFL_3050 GRFL_3123 GRFL_3123 GRFL_3154 GRFL_3154 serC serC GRFL_3166 GRFL_3166 GRFL_3182 GRFL_3182 GRFL_3183 GRFL_3183 gcvT gcvT GRFL_3196 GRFL_3196 GRFL_3214 GRFL_3214 GRFL_3223 GRFL_3223 GRFL_3243 GRFL_3243 GRFL_3254 GRFL_3254 GRFL_3280 GRFL_3280 GRFL_3286 GRFL_3286 aroC aroC pfkA-2 pfkA-2 GRFL_3332 GRFL_3332 GRFL_3338 GRFL_3338 GRFL_3355 GRFL_3355 GRFL_3367 GRFL_3367 GRFL_3427 GRFL_3427 GRFL_3472 GRFL_3472 hisI hisI hisF hisF hisA hisA hisH hisH hisB hisB hisC hisC hisD hisD hisG hisG GRFL_3496 GRFL_3496 sucD sucD GRFL_3525 GRFL_3525 GRFL_3529 GRFL_3529 fumC fumC GRFL_3601 GRFL_3601 aroQ aroQ GRFL_3606 GRFL_3606 GRFL_3618 GRFL_3618 GRFL_3627 GRFL_3627
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query proteins and first shell of interactors
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proteins of unknown 3D structure
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a 3D structure is known or predicted
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acsAAcetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (663 aa)
purCPhosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. (317 aa)
GRFL_0036Malto-oligosyltrehalose trehalohydrolase. (595 aa)
proCPyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (268 aa)
proBGlutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (257 aa)
proAGamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (383 aa)
GRFL_0060Threonine synthase. (432 aa)
thrBHomoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (305 aa)
GRFL_0062Aspartokinase; Homoserine dehydrogenase. (815 aa)
GRFL_0063Magnesium chelatase, subunit ChlI. (487 aa)
GRFL_0102Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family. (287 aa)
GRFL_0103dTDP-glucose 4,6-dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. (354 aa)
GRFL_0120Phosphomannomutase; Phosphoglucosamine mutase. (461 aa)
menBNaphthoate synthase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA); Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily. (279 aa)
menD2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylic-acid synthase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). Belongs to the TPP enzyme family. MenD subfamily. (577 aa)
GRFL_0141Isochorismate synthase. (380 aa)
GRFL_0142ComA operon protein 2. (140 aa)
GRFL_0149L-serine dehydratase; Belongs to the iron-sulfur dependent L-serine dehydratase family. (477 aa)
GRFL_0151Alcohol dehydrogenase. (334 aa)
panB3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (272 aa)
GRFL_01592-isopropylmalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. (390 aa)
leuC3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (460 aa)
leuD3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (204 aa)
leuB3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (372 aa)
argHArgininosuccinate lyase. (423 aa)
GRFL_0164Acetylornithine deacetylase. (356 aa)
argBAcetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (258 aa)
GRFL_0167Acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (377 aa)
proC-2Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (263 aa)
argCN-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (319 aa)
GRFL_0170Argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (395 aa)
ilvAThreonine dehydratase biosynthetic; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (422 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (491 aa)
GRFL_0174Acetolactate synthase small subunit. (179 aa)
GRFL_0175Acetolactate synthase large subunit. (576 aa)
ilvDDihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. (557 aa)
GRFL_0190NAD-dependent glyceraldehyde-3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (332 aa)
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (331 aa)
GRFL_0201Cytoplasmic alpha-amylase. (483 aa)
GRFL_0211Aldose 1-epimerase; Converts alpha-aldose to the beta-anomer. (329 aa)
GRFL_0226Dihydrolipoamide dehydrogenase of 2-oxoglutarate dehydrogenase. (467 aa)
ribB3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. (390 aa)
GRFL_0262D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (630 aa)
GRFL_0278ROK family member transcriptional repressor. (306 aa)
GRFL_0280Alpha-glucosidase. (650 aa)
GRFL_0298Aldose 1-epimerase; Converts alpha-aldose to the beta-anomer. (380 aa)
GRFL_0319Aldose 1-epimerase; Converts alpha-aldose to the beta-anomer. (370 aa)
GRFL_0332Beta-glucosidase. (735 aa)
GRFL_03932-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (311 aa)
miaAtRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. (302 aa)
GRFL_0419Enoyl-[acyl-carrier-protein] reductase [NADH]. (273 aa)
dapADihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (291 aa)
GRFL_04295'-nucleotidase; Belongs to the 5'-nucleotidase family. (301 aa)
GRFL_0435Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (325 aa)
dapFDiaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (269 aa)
GRFL_0448NAD-dependent glyceraldehyde-3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (482 aa)
GRFL_0453Monomeric isocitrate dehydrogenase [NADP]; Belongs to the monomeric-type IDH family. (743 aa)
accAAcetyl-coenzyme A carboxyl transferase alpha chain; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (317 aa)
GRFL_0471Transketolase, N-terminal section. (281 aa)
GRFL_0472Transketolase, C-terminal section. (317 aa)
aroKShikimate kinase I; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (173 aa)
GRFL_0482Phytoene dehydrogenase. (488 aa)
GRFL_0483Phytoene synthase. (284 aa)
GRFL_0484Beta-carotene hydroxylase. (149 aa)
GRFL_0485Lycopene beta cyclase. (378 aa)
GRFL_0487Aconitate hydratase. (755 aa)
guaBInosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (490 aa)
GRFL_0501Hydroxymethylglutaryl-CoA lyase. (274 aa)
GRFL_0509Leucine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (367 aa)
GRFL_0528Polyphosphate glucokinase. (248 aa)
GRFL_0585Alpha-glucosidase. (638 aa)
GRFL_0638Anthranilate synthase, aminase component. (464 aa)
GRFL_0639Anthranilate synthase, amidotransferase component. (208 aa)
trpDAnthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (334 aa)
trpCIndole-3-glycerol phosphate synthase; Belongs to the TrpC family. (260 aa)
trpFPhosphoribosylanthranilate isomerase; Belongs to the TrpF family. (232 aa)
trpBTryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (393 aa)
trpATryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (256 aa)
GRFL_0663Phosphatidate cytidylyltransferase. (267 aa)
psdPhosphatidylserine decarboxylase; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). (218 aa)
GRFL_0668Aspartate aminotransferase. (396 aa)
GRFL_0675NAD-dependent glyceraldehyde-3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (335 aa)
GRFL_06903-oxoacyl-[acyl-carrier protein] reductase. (252 aa)
GRFL_0693O-methyltransferase. (215 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (308 aa)
GRFL_0718Asparagine synthetase [glutamine-hydrolyzing]. (536 aa)
GRFL_0766Citrate synthase (si); Belongs to the citrate synthase family. (428 aa)
GRFL_0767Glycogen synthase, ADP-glucose transglucosylase. (515 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (429 aa)
adkAdenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (371 aa)
purKPhosphoribosylaminoimidazole carboxylase ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (386 aa)
purEPhosphoribosylaminoimidazole carboxylase catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (161 aa)
gcvPGlycine dehydrogenase [decarboxylating] (glycine cleavage system P protein); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (949 aa)
GRFL_0834Mannose-1-phosphate guanylyltransferase (GDP). (363 aa)
GRFL_0838Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (557 aa)
pdhAPyruvate dehydrogenase E1 component alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (333 aa)
GRFL_0863Glycerol-3-phosphate dehydrogenase. (547 aa)
GRFL_0927Glucokinase. (371 aa)
GRFL_0957Glutamate synthase [NADPH] large chain. (1507 aa)
GRFL_0958Glutamate synthase [NADPH] small chain. (486 aa)
purHIMP cyclohydrolase; Phosphoribosylaminoimidazolecarboxamide formyltransferase. (510 aa)
surE5-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (262 aa)
GRFL_1008Hydroxymethylglutaryl-CoA reductase; Belongs to the HMG-CoA reductase family. (433 aa)
GRFL_1070Trehalose synthase. (548 aa)
glgB1,4-alpha-glucan (glycogen) branching enzyme, GH-13-type; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily. (635 aa)
GRFL_1072Alpha-glucosidase, family 31 of glycosyl hydrolases; Belongs to the glycosyl hydrolase 31 family. (807 aa)
GRFL_11322-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (310 aa)
GRFL_1172Dihydrolipoamide succinyltransferase component (E2) of 2-oxoglutarate dehydrogenase complex; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (422 aa)
GRFL_11732-oxoglutarate dehydrogenase E1 component. (927 aa)
GRFL_1174Dimethylallyltransferase; (2E,6E)-farnesyl diphosphate synthase; Geranylgeranyl diphosphate synthase; Belongs to the FPP/GGPP synthase family. (324 aa)
GRFL_1234Succinate dehydrogenase cytochrome b subunit. (206 aa)
GRFL_1235Succinate dehydrogenase flavoprotein subunit. (667 aa)
GRFL_1236Succinate dehydrogenase iron-sulfur protein; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (248 aa)
pgiGlucose-6-phosphate isomerase; Belongs to the GPI family. (543 aa)
GRFL_12891-acyl-sn-glycerol-3-phosphate acyltransferase. (249 aa)
GRFL_1294Protoporphyrinogen IX oxidase HemJ. (182 aa)
hemHFerrochelatase, protoheme ferro-lyase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (344 aa)
hemAGlutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (418 aa)
GRFL_1301Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (304 aa)
GRFL_1302Uroporphyrinogen-III synthase, divergent, Flavobacterial type. (219 aa)
hemEUroporphyrinogen III decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. (341 aa)
GRFL_1305Coproporphyrinogen III oxidase, aerobic. (301 aa)
GRFL_1306Porphobilinogen synthase; Belongs to the ALAD family. (306 aa)
GRFL_13271-acyl-sn-glycerol-3-phosphate acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. (246 aa)
GRFL_1335Glucose-1-phosphate thymidylyltransferase. (336 aa)
purDPhosphoribosylamine--glycine ligase; Belongs to the GARS family. (423 aa)
GRFL_1359dTDP-glucose 4,6-dehydratase. (329 aa)
GRFL_1360dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. (281 aa)
GRFL_1361dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. (181 aa)
pgkPhosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (394 aa)
gltXGlutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (498 aa)
GRFL_1387Ribose 5-phosphate isomerase B. (147 aa)
GRFL_1399Putative sugar kinase, ROK family. (281 aa)
GRFL_1449Riboflavin synthase eubacterial/eukaryotic. (195 aa)
GRFL_1454Biotin carboxyl carrier protein of acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (170 aa)
GRFL_1455Biotin carboxylase of acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (444 aa)
asdAspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (329 aa)
GRFL_1487Amidophosphoribosyltransferase. (632 aa)
purNPhosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (197 aa)
acpPAcyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (78 aa)
GRFL_1495Pyruvate kinase; Belongs to the pyruvate kinase family. (476 aa)
GRFL_1506Isoaspartyl aminopeptidase. (356 aa)
GRFL_1508Aldehyde dehydrogenase B; Belongs to the aldehyde dehydrogenase family. (517 aa)
GRFL_1538Glycerol-3-phosphate dehydrogenase [NAD(P)+]; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (331 aa)
GRFL_1552Cystathionine gamma-lyase. (380 aa)
GRFL_1570Periplasmic beta-glucosidase; Belongs to the glycosyl hydrolase 3 family. (746 aa)
dxs1-deoxy-D-xylulose 5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (590 aa)
GRFL_1615Coproporphyrinogen III oxidase, oxygen-independent; Belongs to the anaerobic coproporphyrinogen-III oxidase family. (454 aa)
GRFL_1662Ribose-phosphate pyrophosphokinase. (311 aa)
GRFL_1666Riboflavin kinase; FMN adenylyltransferase; Belongs to the ribF family. (295 aa)
GRFL_1667Vitamin K-dependent gamma-carboxylase. (439 aa)
GRFL_1674D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (326 aa)
GRFL_1679Aspartokinase; Belongs to the aspartokinase family. (417 aa)
fbpFructose-1,6-bisphosphatase, type I; Belongs to the FBPase class 1 family. (348 aa)
panDAspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. (116 aa)
panCPantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (254 aa)
GRFL_1705Glycogen synthase. (270 aa)
GRFL_1773Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (270 aa)
GRFL_1792Hypothetical protein; Similar to (S)-2,3-di-O-geranylgeranylglyceryl phosphate synthase. (300 aa)
GRFL_1793Mevalonate kinase. (312 aa)
GRFL_1795Diphosphomevalonate decarboxylase. (361 aa)
GRFL_1816Fructokinase. (300 aa)
katGCatalase; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity; Belongs to the peroxidase family. Peroxidase/catalase subfamily. (753 aa)
GRFL_1857L-asparaginase. (342 aa)
pckAPhosphoenolpyruvate carboxykinase [ATP]; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (532 aa)
GRFL_1877uroporphyrinogen-III synthase HemD, putative. (248 aa)
GRFL_1901Glutaryl-CoA dehydrogenase. (391 aa)
GRFL_1921Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family. (291 aa)
GRFL_1922dTDP-glucose 4,6-dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. (339 aa)
GRFL_1923Mannose-1-phosphate guanylyltransferase (GDP). (316 aa)
GRFL_1926Sulfate adenylyltransferase subunit 2. (301 aa)
GRFL_1927Sulfate adenylyltransferase subunit 1; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. (418 aa)
gcvHGlycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (126 aa)
ctaBHeme O synthase, protoheme IX farnesyltransferase COX10-CtaB; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group. (303 aa)
GRFL_1999Undecaprenyl diphosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. (246 aa)
hemLGlutamate-1-semialdehyde aminotransferase. (429 aa)
GRFL_2031Aromatic-amino-acid aminotransferase. (396 aa)
GRFL_2061Malonyl CoA-acyl carrier protein transacylase. (294 aa)
GRFL_2080Pyruvate dehydrogenase E1 component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (325 aa)
GRFL_2095Threonine dehydratase, catabolic. (313 aa)
GRFL_2097D-3-phosphoglycerate dehydrogenase. (309 aa)
GRFL_2098Glutaryl-CoA dehydrogenase. (454 aa)
metKS-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (420 aa)
GRFL_2103Aspartokinase; Homoserine dehydrogenase. (1126 aa)
GRFL_2108Uroporphyrinogen-III methyltransferase. (263 aa)
GRFL_2109Siroheme synthase; Precorrin-2 oxidase; Sirohydrochlorin ferrochelatase. (194 aa)
GRFL_21145-methyltetrahydrofolate--homocysteine methyltransferase. (317 aa)
GRFL_21155-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (888 aa)
GRFL_2120Prephenate dehydratase. (275 aa)
GRFL_2121Biosynthetic Aromatic amino acid aminotransferase alpha. (381 aa)
GRFL_2122Prephenate and/or arogenate dehydrogenase (unknown specificity). (294 aa)
GRFL_21232-keto-3-deoxy-D-arabino-heptulosonate-7- phosphate synthase I beta; Chorismate mutase I. (363 aa)
aroA5-Enolpyruvylshikimate-3-phosphate synthase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (405 aa)
GRFL_2133Octaprenyl-diphosphate synthase; Dimethylallyltransferase; Geranyltranstransferase (farnesyldiphosphate synthase); Geranylgeranyl pyrophosphate synthetase; Belongs to the FPP/GGPP synthase family. (325 aa)
GRFL_2149Periplasmic beta-glucosidase; Belongs to the glycosyl hydrolase 3 family. (760 aa)
fbp-2Fructose-1,6-bisphosphatase, type I; Belongs to the FBPase class 1 family. (334 aa)
GRFL_2189Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (487 aa)
GRFL_2191Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (220 aa)
accDAcetyl-coenzyme A carboxyl transferase beta chain; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA. (288 aa)
GRFL_2197Fructose-bisphosphate aldolase class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (355 aa)
menGUbiquinone/menaquinone biosynthesis methyltransferase UbiE; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2). (243 aa)
GRFL_2207Aspartate aminotransferase. (415 aa)
gpmI2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (504 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (250 aa)
GRFL_2250Beta-galactosidase; Belongs to the glycosyl hydrolase 2 family. (614 aa)
GRFL_2257Hypothetical protein. (1133 aa)
GRFL_2268Aldose 1-epimerase; Converts alpha-aldose to the beta-anomer. (400 aa)
talTransaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. (218 aa)
GRFL_2281Mannose-1-phosphate guanylyltransferase (GDP). (364 aa)
GRFL_2304Phosphoribosylformylglycinamidine cyclo-ligase. (392 aa)
GRFL_2327Branched-chain amino acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (355 aa)
GRFL_2397Phosphoribosylglycinamide formyltransferase. (250 aa)
GRFL_2399Asparagine synthetase [glutamine-hydrolyzing]. (569 aa)
GRFL_2415CDP-diacylglycerol--serine O-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (246 aa)
GRFL_2427Cystathionine beta-synthase. (326 aa)
GRFL_2433Butyryl-CoA dehydrogenase. (388 aa)
GRFL_2435Cytoplasmic alpha-amylase. (458 aa)
GRFL_2456Isopentenyl-diphosphate delta-isomerase. (171 aa)
mqoMalate:quinone oxidoreductase. (497 aa)
menA1,4-dihydroxy-2-naphthoate octaprenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily. (300 aa)
GRFL_2504O-succinylbenzoate synthase. (344 aa)
GRFL_2506O-succinylbenzoic acid--CoA ligase. (365 aa)
GRFL_2526Heme A synthase, cytochrome oxidase biogenesis protein Cox15-CtaA. (342 aa)
GRFL_2542Hypothetical protein. (169 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (424 aa)
tal-2Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. (218 aa)
GRFL_2560Dihydrolipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex. (446 aa)
GRFL_2574Fructose-bisphosphate aldolase class I. (220 aa)
lysADiaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (425 aa)
sucCSuccinyl-CoA ligase [ADP-forming] beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (397 aa)
GRFL_2615Trehalase. (539 aa)
GRFL_2621Cystathionine gamma-lyase. (382 aa)
GRFL_2626Shikimate 5-dehydrogenase I alpha. (241 aa)
GRFL_2630Acetylornithine aminotransferase (ACOAT); Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (394 aa)
GRFL_2637CAAX prenyl protease 1, putative. (413 aa)
ndkNucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (139 aa)
ribH6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. (168 aa)
dapBDihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (237 aa)
GRFL_2776Putative 5'(3')-deoxyribonucleotidase. (177 aa)
GRFL_2858D-threo-aldose 1-dehydrogenase. (331 aa)
GRFL_2863Propionyl-CoA carboxylase beta chain. (513 aa)
GRFL_2864D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (303 aa)
GRFL_2911Hypothetical protein. (1108 aa)
GRFL_2912Hypothetical protein. (1084 aa)
GRFL_2915Hypothetical protein. (296 aa)
GRFL_2922Alpha,alpha-trehalose-phosphate synthase [UDP-forming]; Trehalose-6-phosphate phosphatase. (738 aa)
GRFL_2925Gluconolactonase. (285 aa)
GRFL_29273-ketoacyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (397 aa)
purLPhosphoribosylformylglycinamidine synthase, synthetase subunit; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. (1220 aa)
GRFL_2942Phosphoglucomutase. (576 aa)
GRFL_2973Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (445 aa)
GRFL_3040NAD(P)-dependent glyceraldehyde 3-phosphate dehydrogenase archaeal. (337 aa)
GRFL_3041Fructose-bisphosphate aldolase class I. (353 aa)
GRFL_30436-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. (304 aa)
GRFL_3050Ribose-phosphate pyrophosphokinase; Belongs to the ribose-phosphate pyrophosphokinase family. (297 aa)
GRFL_3123Aminodeoxychorismate lyase. (281 aa)
GRFL_3154D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (315 aa)
serCPhosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (354 aa)
GRFL_3166Trehalose synthase. (1097 aa)
GRFL_31823-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (376 aa)
GRFL_3183Carbapenem antibiotics biosynthesis protein carD. (399 aa)
gcvTAminomethyltransferase (glycine cleavage system T protein); The glycine cleavage system catalyzes the degradation of glycine. (360 aa)
GRFL_3196Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (393 aa)
GRFL_32143-oxoacyl-[acyl-carrier protein] reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (236 aa)
GRFL_3223Serine acetyltransferase. (263 aa)
GRFL_3243Aspartokinase; Belongs to the aspartokinase family. (444 aa)
GRFL_32546-phosphogluconate dehydrogenase, decarboxylating; Belongs to the 6-phosphogluconate dehydrogenase family. (627 aa)
GRFL_3280Aconitate hydratase. (661 aa)
GRFL_3286Branched-chain alpha-keto acid dehydrogenase, E1 component, beta subunit. (668 aa)
aroCChorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (354 aa)
pfkA-26-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (328 aa)
GRFL_3332Acyl carrier protein. (85 aa)
GRFL_33383-oxoacyl-[acyl-carrier protein] reductase. (243 aa)
GRFL_3355Catalase; Serves to protect cells from the toxic effects of hydrogen peroxide. (709 aa)
GRFL_3367Mannose-6-phosphate isomerase. (323 aa)
GRFL_3427Dihydrolipoamide dehydrogenase of 2-oxoglutarate dehydrogenase. (467 aa)
GRFL_34726-phosphogluconolactonase. (378 aa)
hisIPhosphoribosyl-AMP cyclohydrolase; Phosphoribosyl-ATP pyrophosphatase; In the N-terminal section; belongs to the PRA-CH family. (206 aa)
hisFImidazole glycerol phosphate synthase cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (251 aa)
hisAPhosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase. (242 aa)
hisHImidazole glycerol phosphate synthase amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (193 aa)
hisBHistidinol-phosphatase; Imidazoleglycerol-phosphate dehydratase; In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family. (379 aa)
hisCHistidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (350 aa)
hisDHistidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (428 aa)
hisGATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily. (286 aa)
GRFL_34963-oxoacyl-[acyl-carrier protein] reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (248 aa)
sucDSuccinyl-CoA ligase [ADP-forming] alpha chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (291 aa)
GRFL_3525Cystathionine beta-synthase. (346 aa)
GRFL_3529L-allo-threonine aldolase. (343 aa)
fumCFumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (456 aa)
GRFL_3601Dihydrolipoamide dehydrogenase of branched-chain alpha-keto acid dehydrogenase; Dihydrolipoamide dehydrogenase. (463 aa)
aroQ3-dehydroquinate dehydratase II; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (126 aa)
GRFL_3606Aldo-keto reductase family 1 member B10. (315 aa)
GRFL_3618Ornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (427 aa)
GRFL_3627Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (507 aa)
Your Current Organism:
Gramella flava
NCBI taxonomy Id: 1229726
Other names: G. flava JLT2011, Gramella flava JLT2011, Gramella sp. JLT2011
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