(60 nodes) Lipid localization network (Cytospora leucostoma)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	VPNG_09901	Uncharacterized protein. (280 aa)
	VPNG_09902	Uncharacterized protein. (271 aa)
	VPNG_09754	Non-specific serine/threonine protein kinase. (907 aa)
	VPNG_09591	Uncharacterized protein. (341 aa)
	VPNG_09368	Uncharacterized protein. (584 aa)
	VPNG_09399	VASt domain-containing protein. (1180 aa)
	VPNG_08890	SSD domain-containing protein. (1278 aa)
	VPNG_09136	F-box domain-containing protein. (538 aa)
	VPNG_09266	CRAL-TRIO domain-containing protein. (357 aa)
	VPNG_08602	Uncharacterized protein; Belongs to the CDC50/LEM3 family. (421 aa)
	VPNG_08606	SCP2 domain-containing protein. (126 aa)
	VPNG_08570	Oligosaccharide translocation protein RFT1; May participate in the translocation of oligosaccharide from the cytoplasmic side to the lumenal side of the endoplasmic reticulum membrane; Belongs to the RFT1 family. (590 aa)
	VPNG_08511	SCP domain-containing protein; Belongs to the CRISP family. (261 aa)
	VPNG_07716	PRELI/MSF1 domain-containing protein. (188 aa)
	VPNG_07977	GLTP domain-containing protein. (219 aa)
	VPNG_07820	Uncharacterized protein. (651 aa)
	VPNG_07680	Uncharacterized protein. (453 aa)
	VPNG_07882	ABC transporter domain-containing protein. (719 aa)
	VPNG_07195	SCP domain-containing protein; Belongs to the CRISP family. (249 aa)
	VPNG_07205	Uncharacterized protein. (1257 aa)
	VPNG_06992	Uncharacterized protein. (702 aa)
	VPNG_06988	AMP-binding domain-containing protein. (655 aa)
	VPNG_06663	ML domain-containing protein. (172 aa)
	VPNG_07377	SMP-LTD domain-containing protein. (987 aa)
	VPNG_05727	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1315 aa)
	VPNG_05790	Protein kinase domain-containing protein. (361 aa)
	VPNG_06342	Uncharacterized protein. (82 aa)
	VPNG_06325	CRAL-TRIO domain-containing protein. (342 aa)
	VPNG_06481	PH domain-containing protein. (995 aa)
	VPNG_06582	PRELI/MSF1 domain-containing protein. (233 aa)
	VPNG_05927	Uncharacterized protein. (1421 aa)
	VPNG_05926	DUF3074 domain-containing protein. (729 aa)
	VPNG_04834	Uncharacterized protein. (288 aa)
	VPNG_04832	Uncharacterized protein. (627 aa)
	MDM12	Mitochondrial distribution and morphology protein 12; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM12 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10. The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pat [...] (492 aa)
	VPNG_04299	Uncharacterized protein. (607 aa)
	VPNG_03223	ML domain-containing protein. (176 aa)
	VPNG_03797	Uncharacterized protein. (1505 aa)
	VPNG_03795	Uncharacterized protein; Belongs to the OSBP family. (516 aa)
	VPNG_03818	Uncharacterized protein. (833 aa)
	VPNG_03432	Uncharacterized protein. (360 aa)
	VPNG_02017	Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (910 aa)
	VPNG_02059	Uncharacterized protein; Belongs to the OSBP family. (466 aa)
	VPNG_02048	Uncharacterized protein. (295 aa)
	VPNG_02081	CRAL-TRIO domain-containing protein. (464 aa)
	VPNG_02867	SCP domain-containing protein; Belongs to the CRISP family. (293 aa)
	VPNG_01460	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1437 aa)
	VPNG_02721	Uncharacterized protein; Belongs to the OSBP family. (1192 aa)
	VPNG_01341	Vacuolar protein sorting-associated protein; May be involved in recycling of membrane proteins between an endocytic compartment and the TGN; Belongs to the VPS13 family. (3214 aa)
	MDM34	Mitochondrial distribution and morphology protein 34; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10. (540 aa)
	VPNG_01189	Uncharacterized protein. (1206 aa)
	VPNG_00953	Non-specific serine/threonine protein kinase. (854 aa)
	VPNG_00863	Uncharacterized protein. (187 aa)
	VPNG_00562	Uncharacterized protein. (318 aa)
	VPNG_00835	Uncharacterized protein. (1646 aa)
	MMM1	Maintenance of mitochondrial morphology protein 1; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all outer membrane beta- barrel proteins, and acts in a late step after the SAM complex. The MDM10-MDM12-MMM1 su [...] (434 aa)
	VPNG_00069	DUF3074 domain-containing protein. (522 aa)
	VPNG_00046	Uncharacterized protein; Belongs to the OSBP family. (415 aa)
	VPNG_00194	Uncharacterized protein. (571 aa)
	VPNG_00160	Uncharacterized protein. (174 aa)

Your Current Organism:

Cytospora leucostoma

NCBI taxonomy Id: 1230097
Other names: C. leucostoma, Leucostoma leucostoma, Leucostoma persoonii, Valsa leucostoma, Valsa persoonii

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MDM12	MDM34	A0A423XDQ2	A0A423XLJ5	Mitochondrial distribution and morphology protein 12; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM12 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10. The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pat [...]	Mitochondrial distribution and morphology protein 34; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10.	0.947
MDM12	MMM1	A0A423XDQ2	A0A423XNA0	Mitochondrial distribution and morphology protein 12; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM12 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10. The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pat [...]	Maintenance of mitochondrial morphology protein 1; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all outer membrane beta- barrel proteins, and acts in a late step after the SAM complex. The MDM10-MDM12-MMM1 su [...]	0.982
MDM12	VPNG_01341	A0A423XDQ2	A0A423XL60	Mitochondrial distribution and morphology protein 12; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM12 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10. The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pat [...]	Vacuolar protein sorting-associated protein; May be involved in recycling of membrane proteins between an endocytic compartment and the TGN; Belongs to the VPS13 family.	0.424
MDM12	VPNG_06342	A0A423XDQ2	A0A423X212	Mitochondrial distribution and morphology protein 12; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM12 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10. The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pat [...]	Uncharacterized protein.	0.496
MDM12	VPNG_09399	A0A423XDQ2	A0A423VTN5	Mitochondrial distribution and morphology protein 12; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM12 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10. The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pat [...]	VASt domain-containing protein.	0.424
MDM34	MDM12	A0A423XLJ5	A0A423XDQ2	Mitochondrial distribution and morphology protein 34; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10.	Mitochondrial distribution and morphology protein 12; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM12 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10. The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pat [...]	0.947
MDM34	MMM1	A0A423XLJ5	A0A423XNA0	Mitochondrial distribution and morphology protein 34; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10.	Maintenance of mitochondrial morphology protein 1; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all outer membrane beta- barrel proteins, and acts in a late step after the SAM complex. The MDM10-MDM12-MMM1 su [...]	0.955
MMM1	MDM12	A0A423XNA0	A0A423XDQ2	Maintenance of mitochondrial morphology protein 1; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all outer membrane beta- barrel proteins, and acts in a late step after the SAM complex. The MDM10-MDM12-MMM1 su [...]	Mitochondrial distribution and morphology protein 12; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM12 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10. The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pat [...]	0.982
MMM1	MDM34	A0A423XNA0	A0A423XLJ5	Maintenance of mitochondrial morphology protein 1; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all outer membrane beta- barrel proteins, and acts in a late step after the SAM complex. The MDM10-MDM12-MMM1 su [...]	Mitochondrial distribution and morphology protein 34; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10.	0.955
MMM1	VPNG_01341	A0A423XNA0	A0A423XL60	Maintenance of mitochondrial morphology protein 1; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all outer membrane beta- barrel proteins, and acts in a late step after the SAM complex. The MDM10-MDM12-MMM1 su [...]	Vacuolar protein sorting-associated protein; May be involved in recycling of membrane proteins between an endocytic compartment and the TGN; Belongs to the VPS13 family.	0.424
VPNG_00046	VPNG_00953	A0A423XNQ5	A0A423XMI5	Uncharacterized protein; Belongs to the OSBP family.	Non-specific serine/threonine protein kinase.	0.439
VPNG_00046	VPNG_02721	A0A423XNQ5	A0A423XK46	Uncharacterized protein; Belongs to the OSBP family.	Uncharacterized protein; Belongs to the OSBP family.	0.609
VPNG_00046	VPNG_05790	A0A423XNQ5	A0A423X0C0	Uncharacterized protein; Belongs to the OSBP family.	Protein kinase domain-containing protein.	0.439
VPNG_00046	VPNG_06325	A0A423XNQ5	A0A423X285	Uncharacterized protein; Belongs to the OSBP family.	CRAL-TRIO domain-containing protein.	0.660
VPNG_00046	VPNG_06481	A0A423XNQ5	A0A423X2H1	Uncharacterized protein; Belongs to the OSBP family.	PH domain-containing protein.	0.602
VPNG_00046	VPNG_08890	A0A423XNQ5	A0A423VWL4	Uncharacterized protein; Belongs to the OSBP family.	SSD domain-containing protein.	0.548
VPNG_00046	VPNG_09754	A0A423XNQ5	A0A423VLM7	Uncharacterized protein; Belongs to the OSBP family.	Non-specific serine/threonine protein kinase.	0.439
VPNG_00194	VPNG_03432	A0A423XPC1	A0A423XFB7	Uncharacterized protein.	Uncharacterized protein.	0.450
VPNG_00194	VPNG_04299	A0A423XPC1	A0A423XDU1	Uncharacterized protein.	Uncharacterized protein.	0.409
VPNG_00194	VPNG_06325	A0A423XPC1	A0A423X285	Uncharacterized protein.	CRAL-TRIO domain-containing protein.	0.644