(27 nodes) Riboflavin metabolism network (Cytospora leucostoma)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	VPNG_04476	Flavokinase domain-containing protein. (186 aa)
	VPNG_10353	LMWPc domain-containing protein. (169 aa)
	VPNG_10209	F-box domain-containing protein. (632 aa)
	VPNG_09693	Uncharacterized protein. (237 aa)
	VPNG_09447	Uncharacterized protein. (512 aa)
	VPNG_09471	Uncharacterized protein; Belongs to the histidine acid phosphatase family. (534 aa)
	VPNG_09171	GTP_cyclohydro2 domain-containing protein. (384 aa)
	VPNG_07920	Uncharacterized protein. (307 aa)
	VPNG_07293	Uncharacterized protein; Belongs to the histidine acid phosphatase family. (477 aa)
	VPNG_08495	Uncharacterized protein; Belongs to the histidine acid phosphatase family. (553 aa)
	VPNG_06728	CMP/dCMP-type deaminase domain-containing protein. (168 aa)
	VPNG_06897	PseudoU_synth_2 domain-containing protein. (501 aa)
	VPNG_05379	WD_REPEATS_REGION domain-containing protein. (332 aa)
	VPNG_04063	Uncharacterized protein; Belongs to the histidine acid phosphatase family. (487 aa)
	VPNG_03410	Purple acid phosphatase. (705 aa)
	VPNG_02313	Uncharacterized protein. (522 aa)
	VPNG_01961	FMN_red domain-containing protein. (215 aa)
	VPNG_01668	RibD_C domain-containing protein. (261 aa)
	VPNG_01600	PAPS_reduct domain-containing protein. (259 aa)
	VPNG_01560	Uncharacterized protein. (578 aa)
	VPNG_01561	Uncharacterized protein; Belongs to the histidine acid phosphatase family. (524 aa)
	VPNG_01362	AMP-binding domain-containing protein; Belongs to the histidine acid phosphatase family. (1507 aa)
	VPNG_01327	Uncharacterized protein. (410 aa)
	VPNG_00735	Uncharacterized protein. (168 aa)
	VPNG_00426	6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. (211 aa)
	VPNG_00096	Uncharacterized protein; Belongs to the histidine acid phosphatase family. (596 aa)
	VPNG_04471	3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. (231 aa)

Your Current Organism:

Cytospora leucostoma

NCBI taxonomy Id: 1230097
Other names: C. leucostoma, Leucostoma leucostoma, Leucostoma persoonii, Valsa leucostoma, Valsa persoonii

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
VPNG_00096	VPNG_03410	A0A423XP49	A0A423XFT1	Uncharacterized protein; Belongs to the histidine acid phosphatase family.	Purple acid phosphatase.	0.473
VPNG_00426	VPNG_01668	A0A423XP14	A0A423XK07	6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.	RibD_C domain-containing protein.	0.765
VPNG_00426	VPNG_02313	A0A423XP14	A0A423XH41	6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.	Uncharacterized protein.	0.943
VPNG_00426	VPNG_04471	A0A423XP14	A0A423XC35	6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.	3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.	0.987
VPNG_00426	VPNG_04476	A0A423XP14	A0A423XC12	6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.	Flavokinase domain-containing protein.	0.988
VPNG_00426	VPNG_06728	A0A423XP14	A0A423WTK1	6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.	CMP/dCMP-type deaminase domain-containing protein.	0.510
VPNG_00426	VPNG_09171	A0A423XP14	A0A423VYF7	6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.	GTP_cyclohydro2 domain-containing protein.	0.977
VPNG_00426	VPNG_09693	A0A423XP14	A0A423VJQ1	6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.	Uncharacterized protein.	0.997
VPNG_00426	VPNG_10209	A0A423XP14	A0A423VE62	6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.	F-box domain-containing protein.	0.943
VPNG_00735	VPNG_01327	A0A423XN65	A0A423XLR4	Uncharacterized protein.	Uncharacterized protein.	0.568
VPNG_00735	VPNG_03410	A0A423XN65	A0A423XFT1	Uncharacterized protein.	Purple acid phosphatase.	0.755
VPNG_00735	VPNG_07920	A0A423XN65	A0A423WAS7	Uncharacterized protein.	Uncharacterized protein.	0.568
VPNG_00735	VPNG_10353	A0A423XN65	A0A423VAY1	Uncharacterized protein.	LMWPc domain-containing protein.	0.758
VPNG_01327	VPNG_00735	A0A423XLR4	A0A423XN65	Uncharacterized protein.	Uncharacterized protein.	0.568
VPNG_01327	VPNG_01560	A0A423XLR4	A0A423XKF2	Uncharacterized protein.	Uncharacterized protein.	0.414
VPNG_01327	VPNG_01561	A0A423XLR4	A0A423XKX6	Uncharacterized protein.	Uncharacterized protein; Belongs to the histidine acid phosphatase family.	0.414
VPNG_01327	VPNG_01600	A0A423XLR4	A0A423XKA7	Uncharacterized protein.	PAPS_reduct domain-containing protein.	0.735
VPNG_01327	VPNG_03410	A0A423XLR4	A0A423XFT1	Uncharacterized protein.	Purple acid phosphatase.	0.819
VPNG_01327	VPNG_07293	A0A423XLR4	A0A423WKP9	Uncharacterized protein.	Uncharacterized protein; Belongs to the histidine acid phosphatase family.	0.452
VPNG_01327	VPNG_08495	A0A423XLR4	A0A423WRD2	Uncharacterized protein.	Uncharacterized protein; Belongs to the histidine acid phosphatase family.	0.731