STRINGSTRING
GCA_000613385_01330 GCA_000613385_01330 groS groS GCA_000613385_01332 GCA_000613385_01332 groL groL grpE grpE GCA_000613385_01528 GCA_000613385_01528 dnaJ dnaJ GCA_000613385_02062 GCA_000613385_02062 D7Y07_12455 D7Y07_12455 GCA_000613385_02064 GCA_000613385_02064 GCA_000613385_02685 GCA_000613385_02685 GCA_000613385_02686 GCA_000613385_02686 ftsH ftsH clpP clpP clpX clpX GCA_000613385_03146 GCA_000613385_03146 GCA_000613385_03147 GCA_000613385_03147 GCA_000613385_03148 GCA_000613385_03148 lon lon GCA_000613385_04098 GCA_000613385_04098 clpB clpB dnaK dnaK GCA_000613385_04159 GCA_000613385_04159
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GCA_000613385_01330Unannotated protein. (35 aa)
groSUnannotated protein; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. (55 aa)
GCA_000613385_01332Unannotated protein. (126 aa)
groLUnannotated protein; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. (380 aa)
grpEUnannotated protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depe [...] (194 aa)
GCA_000613385_01528Unannotated protein. (191 aa)
dnaJUnannotated protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK [...] (204 aa)
GCA_000613385_02062Unannotated protein. (211 aa)
D7Y07_12455Unannotated protein; Belongs to the ClpA/ClpB family. (350 aa)
GCA_000613385_02064Unannotated protein. (273 aa)
GCA_000613385_02685Unannotated protein. (185 aa)
GCA_000613385_02686Unannotated protein. (112 aa)
ftsHUnannotated protein; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. (407 aa)
clpPUnannotated protein; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. (244 aa)
clpXUnannotated protein; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. (414 aa)
GCA_000613385_03146Unannotated protein. (178 aa)
GCA_000613385_03147Unannotated protein. (106 aa)
GCA_000613385_03148Unannotated protein. (563 aa)
lonUnannotated protein; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. (822 aa)
GCA_000613385_04098Unannotated protein. (339 aa)
clpBUnannotated protein; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. (523 aa)
dnaKUnannotated protein; Acts as a chaperone; Belongs to the heat shock protein 70 family. (637 aa)
GCA_000613385_04159Unannotated protein. (353 aa)
Your Current Organism:
Bacteroides acidifaciens
NCBI taxonomy Id: 1235814
Other names: B. acidifaciens JCM 10556, Bacteroides acidifaciens JCM 10556
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