STRINGSTRING
D7Y07_11190 D7Y07_11190 apt apt murI murI purT purT D7Y07_19725 D7Y07_19725 purA purA GCA_000613385_01320 GCA_000613385_01320 GCA_000613385_01321 GCA_000613385_01321 D7Y07_20380 D7Y07_20380 GCA_000613385_01547 GCA_000613385_01547 purE purE D7Y07_03920 D7Y07_03920 GCA_000613385_02319 GCA_000613385_02319 guaA guaA purD purD guaB guaB purH purH D7Y07_12695 D7Y07_12695 GCA_000613385_03739 GCA_000613385_03739 GCA_000613385_03740 GCA_000613385_03740 GCA_000613385_03741 GCA_000613385_03741 purL purL gmk gmk purC purC D7Y07_06895 D7Y07_06895 D7Y07_09375 D7Y07_09375 adk adk hpt hpt D7Y07_09965 D7Y07_09965 purN purN
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
D7Y07_11190Unannotated protein; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (448 aa)
aptUnannotated protein; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (176 aa)
murIUnannotated protein; Provides the (R)-glutamate required for cell wall biosynthesis. (280 aa)
purTUnannotated protein; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family. (388 aa)
D7Y07_19725Unannotated protein; Belongs to the Fur family. (162 aa)
purAUnannotated protein; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (234 aa)
GCA_000613385_01320Unannotated protein. (152 aa)
GCA_000613385_01321Unannotated protein. (48 aa)
D7Y07_20380Unannotated protein. (220 aa)
GCA_000613385_01547Unannotated protein. (168 aa)
purEUnannotated protein; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (169 aa)
D7Y07_03920Unannotated protein; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (194 aa)
GCA_000613385_02319Unannotated protein. (243 aa)
guaAUnannotated protein; Catalyzes the synthesis of GMP from XMP. (267 aa)
purDUnannotated protein; Belongs to the GARS family. (424 aa)
guaBUnannotated protein; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (492 aa)
purHUnannotated protein. (507 aa)
D7Y07_12695Unannotated protein. (627 aa)
GCA_000613385_03739Unannotated protein. (150 aa)
GCA_000613385_03740Unannotated protein. (122 aa)
GCA_000613385_03741Unannotated protein. (116 aa)
purLUnannotated protein; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. (833 aa)
gmkUnannotated protein; Essential for recycling GMP and indirectly, cGMP. (189 aa)
purCUnannotated protein; Belongs to the SAICAR synthetase family. (314 aa)
D7Y07_06895Unannotated protein. (388 aa)
D7Y07_09375Unannotated protein; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (469 aa)
adkUnannotated protein; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (189 aa)
hptUnannotated protein; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (178 aa)
D7Y07_09965Unannotated protein. (176 aa)
purNUnannotated protein; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (207 aa)
Your Current Organism:
Bacteroides acidifaciens
NCBI taxonomy Id: 1235814
Other names: B. acidifaciens JCM 10556, Bacteroides acidifaciens JCM 10556
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