STRINGSTRING
recN recN GCA_000613385_00092 GCA_000613385_00092 D7Y07_17790 D7Y07_17790 ruvC ruvC D7Y07_02190 D7Y07_02190 D7Y07_02215 D7Y07_02215 D7Y07_02220 D7Y07_02220 ligA ligA nfo nfo GCA_000613385_00565 GCA_000613385_00565 GCA_000613385_00566 GCA_000613385_00566 GCA_000613385_00567 GCA_000613385_00567 GCA_000613385_00568 GCA_000613385_00568 polA polA uvrC uvrC D7Y07_10810 D7Y07_10810 mutY mutY dinB dinB GCA_000613385_00864 GCA_000613385_00864 D7Y07_10890 D7Y07_10890 recQ recQ D7Y07_18015 D7Y07_18015 D7Y07_17955 D7Y07_17955 D7Y07_15890 D7Y07_15890 D7Y07_15975 D7Y07_15975 nth nth ung ung D7Y07_15710 D7Y07_15710 GCA_000613385_01510 GCA_000613385_01510 recR recR GCA_000613385_01774 GCA_000613385_01774 radA radA GCA_000613385_01918 GCA_000613385_01918 ruvA ruvA mutS mutS GCA_000613385_01985 GCA_000613385_01985 GCA_000613385_01986 GCA_000613385_01986 D7Y07_03890 D7Y07_03890 GCA_000613385_01997 GCA_000613385_01997 GCA_000613385_01998 GCA_000613385_01998 D7Y07_13380 D7Y07_13380 GCA_000613385_02158 GCA_000613385_02158 mfd mfd GCA_000613385_02170 GCA_000613385_02170 uvrA uvrA GCA_000613385_02339 GCA_000613385_02339 recF recF D7Y07_10250 D7Y07_10250 ruvB ruvB recG recG recJ recJ GCA_000613385_02575 GCA_000613385_02575 GCA_000613385_02576 GCA_000613385_02576 D7Y07_02655 D7Y07_02655 GCA_000613385_02892 GCA_000613385_02892 D7Y07_07815 D7Y07_07815 D7Y07_10275 D7Y07_10275 D7Y07_09570 D7Y07_09570 recQ-2 recQ-2 mutL mutL GCA_000613385_03160 GCA_000613385_03160 D7Y07_04165 D7Y07_04165 lon lon GCA_000613385_03275 GCA_000613385_03275 uvrB uvrB D7Y07_04030 D7Y07_04030 D7Y07_12120 D7Y07_12120 GCA_000613385_03726 GCA_000613385_03726 uvrA-2 uvrA-2 GCA_000613385_03936 GCA_000613385_03936 D7Y07_09400 D7Y07_09400 clpB clpB recA recA GCA_000613385_04138 GCA_000613385_04138 trxB trxB mutS2 mutS2 recO recO
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
recNUnannotated protein; May be involved in recombinational repair of damaged DNA. (553 aa)
GCA_000613385_00092Unannotated protein. (370 aa)
D7Y07_17790Unannotated protein. (105 aa)
ruvCUnannotated protein; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. (188 aa)
D7Y07_02190Unannotated protein. (192 aa)
D7Y07_02215Unannotated protein. (422 aa)
D7Y07_02220Unannotated protein. (257 aa)
ligAUnannotated protein; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. (666 aa)
nfoUnannotated protein; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin. (277 aa)
GCA_000613385_00565Unannotated protein. (237 aa)
GCA_000613385_00566Unannotated protein. (423 aa)
GCA_000613385_00567Unannotated protein. (53 aa)
GCA_000613385_00568Unannotated protein. (153 aa)
polAUnannotated protein; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. (724 aa)
uvrCUnannotated protein; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. (633 aa)
D7Y07_10810Unannotated protein. (200 aa)
mutYUnannotated protein; Adenine glycosylase active on G-A mispairs. (349 aa)
dinBUnannotated protein; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. (379 aa)
GCA_000613385_00864Unannotated protein. (681 aa)
D7Y07_10890Unannotated protein. (423 aa)
recQUnannotated protein. (602 aa)
D7Y07_18015Unannotated protein; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (205 aa)
D7Y07_17955Unannotated protein. (338 aa)
D7Y07_15890Unannotated protein. (227 aa)
D7Y07_15975Unannotated protein. (115 aa)
nthUnannotated protein; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (225 aa)
ungUnannotated protein; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. (209 aa)
D7Y07_15710Unannotated protein; Belongs to the DNA mismatch repair MutS family. (608 aa)
GCA_000613385_01510Unannotated protein. (87 aa)
recRUnannotated protein; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. (190 aa)
GCA_000613385_01774Unannotated protein. (260 aa)
radAUnannotated protein; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. (455 aa)
GCA_000613385_01918Unannotated protein. (225 aa)
ruvAUnannotated protein; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. (202 aa)
mutSUnannotated protein; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. (492 aa)
GCA_000613385_01985Unannotated protein. (97 aa)
GCA_000613385_01986Unannotated protein. (277 aa)
D7Y07_03890Unannotated protein. (413 aa)
GCA_000613385_01997Unannotated protein. (85 aa)
GCA_000613385_01998Unannotated protein. (123 aa)
D7Y07_13380Unannotated protein. (181 aa)
GCA_000613385_02158Unannotated protein. (236 aa)
mfdUnannotated protein; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. (1052 aa)
GCA_000613385_02170Unannotated protein. (72 aa)
uvrAUnannotated protein; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (841 aa)
GCA_000613385_02339Unannotated protein. (111 aa)
recFUnannotated protein; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family. (219 aa)
D7Y07_10250Unannotated protein; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. (177 aa)
ruvBUnannotated protein; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (344 aa)
recGUnannotated protein; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. (640 aa)
recJUnannotated protein. (349 aa)
GCA_000613385_02575Unannotated protein. (158 aa)
GCA_000613385_02576Unannotated protein. (61 aa)
D7Y07_02655Unannotated protein. (285 aa)
GCA_000613385_02892Unannotated protein. (163 aa)
D7Y07_07815Unannotated protein. (183 aa)
D7Y07_10275Unannotated protein. (354 aa)
D7Y07_09570Unannotated protein. (357 aa)
recQ-2Unannotated protein. (726 aa)
mutLUnannotated protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. (430 aa)
GCA_000613385_03160Unannotated protein. (211 aa)
D7Y07_04165Unannotated protein. (308 aa)
lonUnannotated protein; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. (822 aa)
GCA_000613385_03275Unannotated protein. (184 aa)
uvrBUnannotated protein; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the [...] (677 aa)
D7Y07_04030Unannotated protein. (159 aa)
D7Y07_12120Unannotated protein. (291 aa)
GCA_000613385_03726Unannotated protein. (182 aa)
uvrA-2Unannotated protein; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (923 aa)
GCA_000613385_03936Unannotated protein. (765 aa)
D7Y07_09400Unannotated protein. (140 aa)
clpBUnannotated protein; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. (523 aa)
recAUnannotated protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. (345 aa)
GCA_000613385_04138Unannotated protein. (225 aa)
trxBUnannotated protein. (283 aa)
mutS2Unannotated protein; Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity; Belongs to the DNA mismatch repair MutS family. MutS2 subfamily. (833 aa)
recOUnannotated protein; Involved in DNA repair and RecF pathway recombination. (242 aa)
Your Current Organism:
Bacteroides acidifaciens
NCBI taxonomy Id: 1235814
Other names: B. acidifaciens JCM 10556, Bacteroides acidifaciens JCM 10556
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