(42 nodes) Nicotinate and nicotinamide metabolism network (Fulvivirga imtechensis)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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	C900_00068	Chitinase. (1509 aa)
	C900_00328	Glutathione-regulated potassium-efflux system protein KefC; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. (660 aa)
	C900_00330	Nicotinamidase. (199 aa)
	C900_00331	Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. (468 aa)
	C900_00537	Isoquinoline 1-oxidoreductase beta subunit. (728 aa)
	C900_00736	Potassium voltage-gated channel subfamily KQT. (275 aa)
	C900_00984	NADH pyrophosphatase. (300 aa)
	C900_01014	Nicotinate-nucleotide adenylyltransferase; Belongs to the NadD family. (155 aa)
	cobB	NAD-dependent protein deacetylase of SIR2 family; Belongs to the sirtuin family. Class III subfamily. (230 aa)
	C900_01622	NAD synthetase / Glutamine amidotransferase chain of NAD synthetase. (516 aa)
	C900_01805	Potassium voltage-gated channel subfamily KQT. (262 aa)
	C900_02167	Outer membrane lipoprotein-sorting protein. (245 aa)
	C900_02487	Putative 5'(3')-deoxyribonucleotidase. (199 aa)
	C900_02598	Isoquinoline 1-oxidoreductase beta subunit. (747 aa)
	C900_02599	Isoquinoline 1-oxidoreductase alpha subunit. (156 aa)
	C900_02623	Molybdopterin binding motif protein; Belongs to the CinA family. (421 aa)
	C900_02654	Hypothetical protein. (592 aa)
	C900_02698	Hypothetical protein. (257 aa)
	nadK	NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (291 aa)
	C900_02752	Trk system potassium uptake protein TrkA. (447 aa)
	C900_02848	Nuclease (SNase-like). (160 aa)
	C900_02884	K+ uptake transporter, KtrA subunit. (210 aa)
	C900_02926	Outer membrane lipoprotein carrier protein LolA. (212 aa)
	C900_03144	Ribosylnicotinamide kinase. (184 aa)
	C900_03450	Hypothetical protein. (288 aa)
	C900_03780	Gliding motility-related protein. (206 aa)
	C900_04222	Sulfate permease, Trk-type. (596 aa)
	C900_04263	Purine nucleoside phosphorylase. (238 aa)
	C900_04437	Hypothetical protein. (151 aa)
	C900_04493	Quinolinate phosphoribosyltransferase; Belongs to the NadC/ModD family. (285 aa)
	C900_04572	Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (270 aa)
	C900_04771	Hypothetical protein. (483 aa)
	C900_04791	Hypothetical protein. (144 aa)
	nadA	Quinolinate synthetase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (334 aa)
	C900_04997	L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate. (524 aa)
	C900_05042	Outer membrane lipoprotein-sorting protein. (269 aa)
	C900_05149	Type I restriction-modification system, restriction subunit R. (931 aa)
	C900_05421	2-haloalkanoic acid dehalogenase. (231 aa)
	C900_05503	Endonuclease. (268 aa)
	surE	5-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (256 aa)
	rsfS	Iojap protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. (123 aa)
	C900_05884	Hypothetical protein. (251 aa)

Your Current Organism:

Fulvivirga imtechensis

NCBI taxonomy Id: 1237149
Other names: F. imtechensis AK7, Fulvivirga imtechensis AK7, Fulvivirga sp. AK7

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C900_00068	C900_03144	C900_00068	C900_03144	Chitinase.	Ribosylnicotinamide kinase.	0.429
C900_00068	C900_04263	C900_00068	C900_04263	Chitinase.	Purine nucleoside phosphorylase.	0.439
C900_00068	surE	C900_00068	C900_05670	Chitinase.	5-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.	0.433
C900_00328	C900_01622	C900_00328	C900_01622	Glutathione-regulated potassium-efflux system protein KefC; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.	NAD synthetase / Glutamine amidotransferase chain of NAD synthetase.	0.564
C900_00328	C900_02623	C900_00328	C900_02623	Glutathione-regulated potassium-efflux system protein KefC; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.	Molybdopterin binding motif protein; Belongs to the CinA family.	0.655
C900_00330	C900_00331	C900_00330	C900_00331	Nicotinamidase.	Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.	0.995
C900_00330	C900_01622	C900_00330	C900_01622	Nicotinamidase.	NAD synthetase / Glutamine amidotransferase chain of NAD synthetase.	0.457
C900_00330	C900_02623	C900_00330	C900_02623	Nicotinamidase.	Molybdopterin binding motif protein; Belongs to the CinA family.	0.443
C900_00330	C900_04493	C900_00330	C900_04493	Nicotinamidase.	Quinolinate phosphoribosyltransferase; Belongs to the NadC/ModD family.	0.503
C900_00330	C900_04572	C900_00330	C900_04572	Nicotinamidase.	Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.	0.880
C900_00330	cobB	C900_00330	C900_01571	Nicotinamidase.	NAD-dependent protein deacetylase of SIR2 family; Belongs to the sirtuin family. Class III subfamily.	0.900
C900_00331	C900_00330	C900_00331	C900_00330	Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.	Nicotinamidase.	0.995
C900_00331	C900_00984	C900_00331	C900_00984	Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.	NADH pyrophosphatase.	0.611
C900_00331	C900_01014	C900_00331	C900_01014	Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.	Nicotinate-nucleotide adenylyltransferase; Belongs to the NadD family.	0.919
C900_00331	C900_01622	C900_00331	C900_01622	Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.	NAD synthetase / Glutamine amidotransferase chain of NAD synthetase.	0.719
C900_00331	C900_02623	C900_00331	C900_02623	Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.	Molybdopterin binding motif protein; Belongs to the CinA family.	0.925
C900_00331	C900_03144	C900_00331	C900_03144	Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.	Ribosylnicotinamide kinase.	0.634
C900_00331	C900_04263	C900_00331	C900_04263	Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.	Purine nucleoside phosphorylase.	0.562
C900_00331	C900_04493	C900_00331	C900_04493	Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.	Quinolinate phosphoribosyltransferase; Belongs to the NadC/ModD family.	0.865
C900_00331	C900_04572	C900_00331	C900_04572	Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.	Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.	0.745