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C943_00084 C943_00084 mdh mdh C943_00569 C943_00569 C943_00570 C943_00570 C943_00571 C943_00571 C943_00731 C943_00731 C943_00797 C943_00797 C943_00986 C943_00986 pckA pckA sucC sucC C943_01083 C943_01083 ackA ackA C943_01157 C943_01157 C943_01371 C943_01371 C943_01477 C943_01477 C943_01478 C943_01478 C943_01479 C943_01479 C943_01507 C943_01507 C943_01557 C943_01557 C943_01849 C943_01849 C943_01894 C943_01894 C943_02101 C943_02101 C943_02156 C943_02156 C943_02328 C943_02328 fumC fumC sucD sucD C943_02555 C943_02555 C943_02730 C943_02730 C943_02834 C943_02834 C943_02861 C943_02861 C943_02893 C943_02893 C943_03030 C943_03030 pdhA pdhA C943_03814 C943_03814 C943_04413 C943_04413 C943_04414 C943_04414 C943_04415 C943_04415
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
C943_00084Pyruvate-flavodoxin oxidoreductase. (1632 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (312 aa)
C943_00569Dihydrolipoamide dehydrogenase of 2-oxoglutarate dehydrogenase. (465 aa)
C943_00570Dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (509 aa)
C943_005712-oxoglutarate dehydrogenase E1 component. (934 aa)
C943_00731Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. (630 aa)
C943_00797Glu/Leu/Phe/Val dehydrogenase family protein. (408 aa)
C943_00986Aspartate ammonia-lyase. (495 aa)
pckAPhosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (535 aa)
sucCSuccinyl-CoA ligase [ADP-forming] beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (405 aa)
C943_01083Ribose-phosphate pyrophosphokinase. (306 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (368 aa)
C943_01157Branched-chain alpha-keto acid dehydrogenasecomponent, beta subunit. (804 aa)
C943_01371Branched-chain alpha-keto acid dehydrogenasecomponent, beta subunit. (668 aa)
C943_01477Succinate dehydrogenase cytochrome b subunit. (226 aa)
C943_01478Succinate dehydrogenase flavoprotein subunit. (644 aa)
C943_01479Succinate dehydrogenase iron-sulfur protein; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (249 aa)
C943_01507Isocitrate dehydrogenase; Belongs to the monomeric-type IDH family. (742 aa)
C943_01557Lactate dehydrogenase like protein. (975 aa)
C943_01849Aspartate aminotransferase. (441 aa)
C943_01894Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (558 aa)
C943_02101Citrate synthase (si); Belongs to the citrate synthase family. (429 aa)
C943_02156Ribose-phosphate pyrophosphokinase. (308 aa)
C943_02328Glutamate synthase [NADPH] large chain. (1496 aa)
fumCFumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (457 aa)
sucDSuccinyl-CoA ligase [ADP-forming] alpha chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (293 aa)
C943_02555Aldehyde dehydrogenase B; Belongs to the aldehyde dehydrogenase family. (514 aa)
C943_02730Dihydrolipoamide dehydrogenase. (466 aa)
C943_02834Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. (698 aa)
C943_02861Hypothetical protein. (134 aa)
C943_02893Dihydrolipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex. (429 aa)
C943_03030Aconitate hydratase. (753 aa)
pdhAPyruvate dehydrogenase E1 component alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (341 aa)
C943_03814Pyruvate dehydrogenase E1 component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (326 aa)
C943_044132-oxoglutarate oxidoreductase, beta subunit. (350 aa)
C943_044142-oxoglutarate oxidoreductase, alpha subunit. (612 aa)
C943_04415Glutamate synthase [NADPH] small chain. (602 aa)
Your Current Organism:
Mariniradius saccharolyticus
NCBI taxonomy Id: 1239962
Other names: Aquiflexum sp. AK6, Cyclobacteriaceae bacterium AK6, M. saccharolyticus AK6, Mariniradius saccharolyticus AK6
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