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| | C943_00737 | Ribose 5-phosphate isomerase B. (145 aa) |
| | glyA | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (422 aa) |
| | gpmI | 2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (500 aa) |
| | C943_00809 | Hypothetical protein. (289 aa) |
| | fbp | Fructose-1,6-bisphosphatase, type I; Belongs to the FBPase class 1 family. (357 aa) |
| | C943_00935 | Enoyl-CoA hydratase. (801 aa) |
| | C943_00938 | Acyl-CoA dehydrogenase, short-chain specific. (599 aa) |
| | C943_00979 | 3-hydroxybutyryl-CoA dehydrogenase. (292 aa) |
| | C943_01025 | D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (630 aa) |
| | pckA | Phosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (535 aa) |
| | sucC | Succinyl-CoA ligase [ADP-forming] beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (405 aa) |
| | C943_01083 | Ribose-phosphate pyrophosphokinase. (306 aa) |
| | ackA | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (368 aa) |
| | C943_01115 | Methylcrotonyl-CoA carboxylase biotin-containing subunit. (426 aa) |
| | C943_01120 | L-serine dehydratase, beta subunit; Belongs to the iron-sulfur dependent L-serine dehydratase family. (225 aa) |
| | pgi | Glucose-6-phosphate isomerase; Belongs to the GPI family. (548 aa) |
| | C943_01185 | Hypothetical protein. (277 aa) |
| | C943_01186 | Hypothetical protein. (284 aa) |
| | C943_01471 | Putative esterase. (287 aa) |
| | C943_01477 | Succinate dehydrogenase cytochrome b subunit. (226 aa) |
| | C943_01478 | Succinate dehydrogenase flavoprotein subunit. (644 aa) |
| | C943_02545 | Methylmalonyl-CoA mutase; Overlaps another CDS with the same product name. (445 aa) |
| | sucD | Succinyl-CoA ligase [ADP-forming] alpha chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (293 aa) |
| | C943_02516 | Hypothetical protein. (174 aa) |
| | C943_02504 | L-serine dehydratase, alpha subunit; Belongs to the iron-sulfur dependent L-serine dehydratase family. (302 aa) |
| | C943_04096 | Transketolase. (322 aa) |
| | fumC | Fumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (457 aa) |
| | C943_02343 | Isocitrate dehydrogenase [NADP]. (478 aa) |
| | C943_02228 | Fructose-bisphosphate aldolase class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (353 aa) |
| | C943_02160 | Lactoylglutathione lyase. (134 aa) |
| | gcvT | Aminomethyltransferase (glycine cleavage system T protein); The glycine cleavage system catalyzes the degradation of glycine. (364 aa) |
| | C943_02156 | Ribose-phosphate pyrophosphokinase. (308 aa) |
| | fhs | Formate--tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family. (557 aa) |
| | C943_02101 | Citrate synthase (si); Belongs to the citrate synthase family. (429 aa) |
| | C943_02099 | acyl-coA-binding protein, ACBP. (86 aa) |
| | C943_02083 | Phosphoglycerate mutase-like protein; Belongs to the phosphoglycerate mutase family. (209 aa) |
| | C943_02078 | PIN domain protein. (128 aa) |
| | pfkA-2 | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. (363 aa) |
| | C943_02015 | Polyphosphate glucokinase. (180 aa) |
| | C943_01998 | Glucokinase. (308 aa) |
| | C943_01996 | Hypothetical protein; Belongs to the ArsC family. (119 aa) |
| | C943_01994 | 3-hydroxybutyryl-CoA dehydrogenase. (297 aa) |
| | C943_01959 | Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. (852 aa) |
| | C943_01894 | Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (558 aa) |
| | C943_04127 | 4-Hydroxy-2-oxoglutarate aldolase. (220 aa) |
| | C943_01882 | Glucokinase. (412 aa) |
| | C943_01773 | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. (351 aa) |
| | pfkA | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (328 aa) |
| | accA | Acetyl-coenzyme A carboxyl transferase alpha chain; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (315 aa) |
| | C943_01658 | NAD-dependent glyceraldehyde-3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (334 aa) |
| | C943_01606 | 3-oxoacyl-[acyl-carrier protein] reductase. (254 aa) |
| | C943_01536 | Pyruvate kinase; Belongs to the pyruvate kinase family. (476 aa) |
| | C943_01507 | Isocitrate dehydrogenase; Belongs to the monomeric-type IDH family. (742 aa) |
| | C943_01479 | Succinate dehydrogenase iron-sulfur protein; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (249 aa) |
| | C943_04095 | Transketolase. (283 aa) |
| | C943_04593 | Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. (901 aa) |
| | C943_04548 | NAD-specific glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (472 aa) |
| | pfkA-3 | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (324 aa) |
| | C943_04513 | D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (309 aa) |
| | C943_04509 | Catalase. (518 aa) |
| | C943_04478 | Muramoyltetrapeptide carboxypeptidase. (353 aa) |
| | C943_04416 | Gluconolactonase. (303 aa) |
| | C943_04415 | Glutamate synthase [NADPH] small chain. (602 aa) |
| | C943_04414 | 2-oxoglutarate oxidoreductase, alpha subunit. (612 aa) |
| | C943_04413 | 2-oxoglutarate oxidoreductase, beta subunit. (350 aa) |
| | C943_04349 | Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (756 aa) |
| | C943_04205 | Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (216 aa) |
| | C943_04128 | 2-dehydro-3-deoxygluconate kinase. (331 aa) |
| | C943_04049 | PilT-like protein. (84 aa) |
| | C943_04041 | Hypothetical protein. (49 aa) |
| | gcvH | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (125 aa) |
| | C943_03991 | Enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (261 aa) |
| | C943_03990 | Isocitrate dehydrogenase [NADP]. (484 aa) |
| | C943_03814 | Pyruvate dehydrogenase E1 component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (326 aa) |
| | tpiA | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (253 aa) |
| | C943_03756 | Gluconolactonase. (312 aa) |
| | C943_03655 | Pyruvate kinase family protein; Belongs to the pyruvate kinase family. (499 aa) |
| | C943_03588 | Hypothetical protein. (641 aa) |
| | C943_03526 | Iron-sulfur-binding reductase. (263 aa) |
| | accD | Acetyl-coenzyme A carboxyl transferase beta chain; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA. (280 aa) |
| | gcvP | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (963 aa) |
| | pgk | Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (399 aa) |
| | C943_03256 | Threonine dehydratase, catabolic. (314 aa) |
| | pdhA | Pyruvate dehydrogenase E1 component alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (341 aa) |
| | C943_03187 | NAD-specific glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (425 aa) |
| | C943_03030 | Aconitate hydratase. (753 aa) |
| | tal | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. (219 aa) |
| | C943_02959 | O-acetylhomoserine sulfhydrylase. (424 aa) |
| | C943_02918 | Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (392 aa) |
| | C943_02909 | 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (317 aa) |
| | C943_02893 | Dihydrolipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex. (429 aa) |
| | icmF | Methylmalonyl-CoA mutase; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly. (1125 aa) |
| | C943_02834 | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. (698 aa) |
| | C943_02812 | NAD-dependent glyceraldehyde-3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (335 aa) |
| | C943_02730 | Dihydrolipoamide dehydrogenase. (466 aa) |
| | C943_02680 | Putative virulence-associated protein. (135 aa) |
| | C943_02609 | Serine acetyltransferase. (277 aa) |
| | C943_02603 | Putative propionyl-CoA carboxylase beta chain protein. (527 aa) |
| | C943_02588 | D-arabino-3-hexulose 6-phosphate formaldehyde lyase. (235 aa) |
| | C943_02546 | Methylmalonyl-CoA mutase; Overlaps another CDS with the same product name. (705 aa) |
| | C943_00039 | 3-carboxymuconate cyclase-like protein. (382 aa) |
| | C943_00084 | Pyruvate-flavodoxin oxidoreductase. (1632 aa) |
| | rnfC | Electron transport complex protein RnfC; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily. (448 aa) |
| | C943_00182 | Biotin carboxyl carrier protein of acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (161 aa) |
| | C943_00183 | Biotin carboxylase of acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (449 aa) |
| | C943_00217 | Hypothetical protein. (405 aa) |
| | folD | Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (294 aa) |
| | C943_00313 | 6-phosphogluconate dehydrogenase, decarboxylating; Belongs to the 6-phosphogluconate dehydrogenase family. (634 aa) |
| | C943_00316 | Putative sugar kinase, ROK family. (316 aa) |
| | C943_00327 | Hypothetical protein; Belongs to the ArsC family. (115 aa) |
| | mdh | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (312 aa) |
| | C943_00403 | Nucleic acid-binding protein. (89 aa) |
| | C943_00455 | L-serine dehydratase. (486 aa) |
| | eno | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (426 aa) |
| | C943_00570 | Dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (509 aa) |
| | C943_00571 | 2-oxoglutarate dehydrogenase E1 component. (934 aa) |
| | C943_00731 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. (630 aa) |
