STRINGSTRING
KSB61286.1 KSB61286.1 rnpA rnpA KSB56124.1 KSB56124.1 KSB56117.1 KSB56117.1 umuD umuD umuC umuC rcsA rcsA SBOV20251 SBOV20251 fliA fliA uvrC uvrC KSB56943.1 KSB56943.1 narZ-2 narZ-2 narH-2 narH-2 trpD trpD trpE trpE fabI fabI hycE hycE nuoB-2 nuoB-2 norW norW recA recA KSB57516.1 KSB57516.1 nrdF nrdF KSB57501.1 KSB57501.1 eno eno cysD cysD cysN cysN cysC cysC mutS mutS KSB57930.1 KSB57930.1 hypB hypB hypA-2 hypA-2 rpoB rpoB rpoC rpoC thiH thiH thiG thiG KSB58550.1 KSB58550.1 KSB58549.1 KSB58549.1 accC accC accB accB tldD tldD sspB sspB KSB58706.1 KSB58706.1 gltB gltB KSB58695.1 KSB58695.1 pnp pnp KSB58842.1 KSB58842.1 KSB58840.1 KSB58840.1 pyk pyk ruvB ruvB ruvA ruvA ruvC ruvC rpoE rpoE yfhL yfhL iscS iscS nifU nifU iscA iscA hscB hscB hscA hscA KSB58932.1 KSB58932.1 dmsB-3 dmsB-3 dmsC_1 dmsC_1 KSB58922.1 KSB58922.1 xseA xseA ppk1 ppk1 KSB58904.1 KSB58904.1 KSB59130.1 KSB59130.1 KSB59090.1 KSB59090.1 KSB59089.1 KSB59089.1 KSB59060.1 KSB59060.1 cybH-2 cybH-2 KSB59367.1 KSB59367.1 prs prs KSB59352.1 KSB59352.1 cobQ cobQ KSB59315.1 KSB59315.1 KSB59314.1 KSB59314.1 hisH hisH uvrD uvrD xerC xerC rhlB rhlB ilvM ilvM KSB59637.1 KSB59637.1 KSB59635.1 KSB59635.1 fdoI fdoI fdxH fdxH fdnG-2 fdnG-2 pfkA pfkA hslU hslU hslV hslV ndh ndh KSB60118.1 KSB60118.1 KSB60715.1 KSB60715.1 KSB60713.1 KSB60713.1 KSB60710.1 KSB60710.1 rpoD rpoD dnaG dnaG hyb0 hyb0 KSB60602.1 KSB60602.1 KSB60601.1 KSB60601.1 KSB60600.1 KSB60600.1 hypA hypA KSB61297.1 KSB61297.1 KSB61294.1 KSB61294.1 fimY fimY dnaQ dnaQ KSB63058.1 KSB63058.1 dinB dinB KSB63043.1 KSB63043.1 KSB63015.1 KSB63015.1 KSB62973.1 KSB62973.1 KSB62918.1 KSB62918.1 ribH ribH nusB nusB xseB xseB KSB62896.1 KSB62896.1 KSB63106.1 KSB63106.1 KSB62895.1 KSB62895.1 cyoD cyoD cyoC cyoC clpX clpX KSB62871.1 KSB62871.1 dnaX dnaX cysK cysK cysM cysM eutC eutC KSB63942.1 KSB63942.1 glyS glyS glyQ glyQ cysE cysE gpsA gpsA radC radC coaBC coaBC rph rph rpoZ rpoZ recG recG ilvN ilvN KSB63807.1 KSB63807.1 KSB63764.1 KSB63764.1 KSB63763.1 KSB63763.1 glpA glpA glpB glpB nuoN nuoN KSB63732.1 KSB63732.1 KSB63731.1 KSB63731.1 nuoK nuoK nuoJ nuoJ nuoI nuoI nuoH nuoH KSB63726.1 KSB63726.1 nuoF nuoF nuoE nuoE nuoC nuoC nuoB nuoB nuoA nuoA KSB63715.1 KSB63715.1 accD accD SBOV24751 SBOV24751 recD recD recB recB recC recC xerD xerD gcvP gcvP gcvH gcvH gcvT gcvT trmB trmB KSB64427.1 KSB64427.1 KSB65782.1 KSB65782.1 nikC nikC KSB65772.1 KSB65772.1 KSB65722.1 KSB65722.1 pheS pheS pheT pheT sufA sufA KSB65671.1 KSB65671.1 KSB65561.1 KSB65561.1 dmsB-2 dmsB-2 KSB65558.1 KSB65558.1 KSB65555.1 KSB65555.1 hypA-3 hypA-3 cybH cybH hyaA2 hyaA2 treZ treZ KSB65492.1 KSB65492.1 fdnH fdnH fdnG fdnG KSB65489.1 KSB65489.1 narZ narZ narH narH nifJ nifJ pgmB pgmB KSB65786.1 KSB65786.1 accA accA dnaE dnaE dgt dgt KSB66643.1 KSB66643.1 lpdA lpdA aceF aceF aceE aceE guaC guaC ilvH ilvH KSB66562.1 KSB66562.1 leuC leuC leuD leuD KSB66542.1 KSB66542.1 carB carB carA carA nadR nadR rimI rimI holD holD KSB66400.1 KSB66400.1 KSB66399.1 KSB66399.1 KSB66398.1 KSB66398.1 KSB66349.1 KSB66349.1 argF-2 argF-2 argF argF pyrB pyrB pyrI pyrI pmbA pmbA KSB66196.1 KSB66196.1 KSB66191.1 KSB66191.1 dmsB dmsB KSB66189.1 KSB66189.1 dcuR dcuR phnG phnG phnH phnH KSB66167.1 KSB66167.1 KSB66166.1 KSB66166.1 phnK phnK phnL phnL KSB66155.1 KSB66155.1 uvrA uvrA rpoA rpoA tusB tusB tusC tusC tusD tusD mdcE mdcE KSB65991.1 KSB65991.1 glpD glpD glgC glgC tusA tusA KSB65875.1 KSB65875.1 KSB67081.1 KSB67081.1 KSB67072.1 KSB67072.1 KSB67071.1 KSB67071.1 KSB67070.1 KSB67070.1 KSB67064.1 KSB67064.1 KSB67046.1 KSB67046.1 ybjQ ybjQ moeB moeB moaE moaE moaD moaD uvrB uvrB sucD sucD sucC sucC KSB66905.1 KSB66905.1 sucA sucA sdhA sdhA sdhC sdhC KSB66891.1 KSB66891.1 holA holA dpiA dpiA KSB66803.1 KSB66803.1 KSB66801.1 KSB66801.1 ahpF ahpF ahpC ahpC
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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KSB61286.1Transcriptional regulator; Regulates type 1 fimbriae expression; Derived by automated computational analysis using gene prediction method: Protein Homology. (198 aa)
rnpARibonuclease P; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. (119 aa)
KSB56124.1DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] (366 aa)
KSB56117.1Catalyzes the reduction of trimethylamine-N-oxide to form trimethylamine; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (850 aa)
umuDBinds with UmuC protein to form functional DNA pol V (UmuD'2UmuC); involved in translesion polymerization; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S24 family. (139 aa)
umuCDNA polymerase V subunit UmuC; Binds processed UmuD protein to form functional DNA pol V (UmuD'2UmuC); involved in translesion polymerization; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DNA polymerase type-Y family. (422 aa)
rcsACapsule biosynthesis protein CapA; Component of the Rcs signaling system, which controls transcription of numerous genes. Binds, with RcsB, to the RcsAB box to regulate expression of genes. (207 aa)
SBOV20251Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sulfur carrier protein TusA family. (77 aa)
fliAFlagellar biosynthesis sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes; Belongs to the sigma-70 factor family. FliA subfamily. (239 aa)
uvrCExcinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. (610 aa)
KSB56943.1Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (174 aa)
narZ-2Nitrate reductase; With NarYV catalyzes the reduction of nitrate; the beta subunit is an iron sulfur cluster containing electron transfer subunit; one of 3 nitrate reductases in E. coli; expression of nitrate reductase Z is not dependent on nitrate levels; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (1247 aa)
narH-2Nitrate reductase; With NarGJI catalyzes the reduction of nitrate; the beta subunit is an iron sulfur cluster containing electron transfer subunit; one of 3 nitrate reductases in E. coli and in E. coli is expressed when nitrate levels are high; Derived by automated computational analysis using gene prediction method: Protein Homology. (511 aa)
trpDGlutamine amidotransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (531 aa)
trpEHypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (520 aa)
fabIenoyl-ACP reductase; Catalyzes a key regulatory step in fatty acid biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. (262 aa)
hycEHydrogenase 3 large subunit; Formate hydrogenlyase subunit 5; HycBCDEFG is part of the formate hydrogenlyase system which is involved in the cleaving of formate to dihydrogen and carbon dioxide; Derived by automated computational analysis using gene prediction method: Protein Homology. (291 aa)
nuoB-2Formate hydrogenlyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (255 aa)
norWNADH:flavorubredoxin oxidoreductase; One of at least two accessory proteins for anaerobic nitric oxide (NO) reductase. Reduces the rubredoxin moiety of NO reductase. (377 aa)
recARecombinase A; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. (353 aa)
KSB57516.16-phosphogluconate phosphatase; YqaB; catalyzes the dephosphorylation of fructose 1-phosphate, 6-phosphogluconate and p-nitrophenyl phosphate (pNPP); presents beta-phosphoglucomutase activity at a lower extent; Derived by automated computational analysis using gene prediction method: Protein Homology. (188 aa)
nrdFRibonucleotide-diphosphate reductase subunit beta; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. (319 aa)
KSB57501.1Hypothetical protein; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (714 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. (309 aa)
cysDSulfate adenylyltransferase subunit 2; With CysN catalyzes the formation of adenylylsulfate from sulfate and ATP; Derived by automated computational analysis using gene prediction method: Protein Homology. (302 aa)
cysNSulfate adenylyltransferase subunit 1; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. (479 aa)
cysCAdenylylsulfate kinase; Catalyzes the synthesis of activated sulfate. (201 aa)
mutSDNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. (853 aa)
KSB57930.1Transcriptional regulator; Activates Salmonella pathogenicity island 4 genes and weakly represses Salmonella pathogenicity island 1 genes; Derived by automated computational analysis using gene prediction method: Protein Homology. (251 aa)
hypBHydrogenase nickel incorporation protein HypB; GTP hydrolase involved in nickel liganding into hydrogenases; Derived by automated computational analysis using gene prediction method: Protein Homology. (290 aa)
hypA-2Hydrogenase nickel incorporation protein; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. (118 aa)
rpoBDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1342 aa)
rpoCDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1407 aa)
thiHIn Escherichia coli this enzyme functions in thiamine biosynthesis along with thiFSGI and iscS; with ThiFSG catalyzes the formation of thiazole phosphate from tyrosine, cysteine and 1-deoxy-D-xylulose-5-phosphate; forms a complex with ThiG; contains an iron-sulfur center; Derived by automated computational analysis using gene prediction method: Protein Homology. (375 aa)
thiGThiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. (256 aa)
KSB58550.1Thiamine biosynthesis protein ThiS; With ThiF, ThiG, and ThiO catalyzes the formation of the thiazole moiety of thiamine pyrophosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. (66 aa)
KSB58549.1Molybdopterin biosynthesis protein MoeB; ATP-dependent adenylate transferase, transfers adenyl moiety to the MoeD subunit of molybdopterin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (252 aa)
accCacetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (449 aa)
accBacetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (156 aa)
tldDProtease TldD; Responsible for the proteolytic maturation of the E. coli pMccB17 plasmid-encoded microcin B17, an exported protein that targets the essential topoisomerase II DNA gyrase; degrades the E. coli plasmid F-encoded CcdA; Derived by automated computational analysis using gene prediction method: Protein Homology. (481 aa)
sspBClp protease ClpP; Derived by automated computational analysis using gene prediction method: Protein Homology. (166 aa)
KSB58706.1Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (472 aa)
gltBCatalyzes the formation of glutamate from glutamine and alpha-ketoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology. (1486 aa)
KSB58695.1RNA polymerase factor sigma-54; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (477 aa)
pnpPolynucleotide phosphorylase/polyadenylase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. (711 aa)
KSB58842.1DNA polymerase III subunit theta; Derived by automated computational analysis using gene prediction method: Protein Homology. (76 aa)
KSB58840.13'-5' exonuclease activity on single or double-strand DNA; Derived by automated computational analysis using gene prediction method: Protein Homology. (232 aa)
pykPyruvate kinase; Catalyzes the formation of phosphoenolpyruvate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology. (480 aa)
ruvBATP-dependent DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (336 aa)
ruvAATP-dependent DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. (203 aa)
ruvCHolliday junction resolvase; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. (173 aa)
rpoERNA polymerase subunit sigma; Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor is involved in heat shock and oxidative stress response; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (191 aa)
yfhLFerredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. (86 aa)
iscSCysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur and selenium atoms from cysteine and selenocysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. Also functions as a selenium delivery protein in the pathway for the biosynthesis of selenophosphate. (404 aa)
nifUScaffolding protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. (128 aa)
iscAIron-sulfur cluster assembly protein; Is able to transfer iron-sulfur clusters to apo-ferredoxin. Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system TrxA/TrxB. (107 aa)
hscBCo-chaperone HscB; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family. (171 aa)
hscAChaperone protein HscA; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. Involved in the maturation of IscU. (616 aa)
KSB58932.1DMSO reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (792 aa)
dmsB-34Fe-4S ferredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. (209 aa)
dmsC_1Dimethyl sulfoxide reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (269 aa)
KSB58922.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (73 aa)
xseAExodeoxyribonuclease VII large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. (454 aa)
ppk1Polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family. (688 aa)
KSB58904.1Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (174 aa)
KSB59130.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (586 aa)
KSB59090.1Dihydropyrimidine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (411 aa)
KSB59089.1Dihydropyrimidine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (413 aa)
KSB59060.1Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (174 aa)
cybH-2Hydrogenase 1 b-type cytochrome subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (243 aa)
KSB59367.1Hydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (372 aa)
prsRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (315 aa)
KSB59352.1Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (174 aa)
cobQCobalamin biosynthesis protein CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. (506 aa)
KSB59315.1Catalyzes the methylation of either C-15 or C-5 in cobalt-precorrin-6Y to form cobalt-precorrin-7W; decarboxylating; Derived by automated computational analysis using gene prediction method: Protein Homology. (192 aa)
KSB59314.1Catalyzes the methylation of C-5 in cobalt-precorrin-6Y to form cobalt-precorrin-7W-a; Derived by automated computational analysis using gene prediction method: Protein Homology. (201 aa)
hisHImidazole glycerol phosphate synthase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (196 aa)
uvrDDNA-dependent helicase II; Unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present; involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair; Derived by automated computational analysis using gene prediction method: Protein Homology. (720 aa)
xerCRecombinase XerC; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Binds cooperatively to specific DNA consensus sequences that are separated from XerD binding sites by a short central region, forming the heterotetrameric XerC-XerD complex that recombines DNA substrates. The complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. In the complex XerC specifically exchanges the top DN [...] (300 aa)
rhlBATP-dependent RNA helicase RhlB; DEAD-box RNA helicase involved in RNA degradation. Has RNA- dependent ATPase activity and unwinds double-stranded RNA. Belongs to the DEAD box helicase family. RhlB subfamily. (421 aa)
ilvMAcetolactate synthase 2 regulatory subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (87 aa)
KSB59637.1Acetolactate synthase catalytic subunit; Catalyzes the formation of 2-acetolactate from pyruvate; also known as acetolactate synthase large subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (548 aa)
KSB59635.1Among the AAA+ ATPases, the YifB protease family belongs to the Helix 2 insert clade; unknown function; Derived by automated computational analysis using gene prediction method: Protein Homology. (506 aa)
fdoIFormate dehydrogenase; Cytochrome b556(FDO) component; heme containing; Derived by automated computational analysis using gene prediction method: Protein Homology. (211 aa)
fdxHFormate dehydrogenase; The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers. (300 aa)
fdnG-2Formate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (804 aa)
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (320 aa)
hslUATP-dependent protease ATP-binding subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. (443 aa)
hslVHypothetical protein; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. Belongs to the peptidase T1B family. HslV subfamily. (176 aa)
ndhNADH dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (434 aa)
KSB60118.1DNA polymerase III subunit delta; Catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA; Derived by automated computational analysis using gene prediction method: Protein Homology. (334 aa)
KSB60715.1Alpha-glucosidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (783 aa)
KSB60713.1Beta-galactosidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1046 aa)
KSB60710.1methionyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (110 aa)
rpoDRNA polymerase subunit sigma; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. (615 aa)
dnaGDNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (581 aa)
hyb0Hydrogenase 2 small subunit; Involved in hydrogen uptake; Derived by automated computational analysis using gene prediction method: Protein Homology. (372 aa)
KSB60602.1Hydrogenase 2 protein HybA; Fe-S ferrodoxin type component; participates in the periplasmic electron-transferring activity of hydrogenase 2; Derived by automated computational analysis using gene prediction method: Protein Homology. (328 aa)
KSB60601.1HybB; cytochrome b subunit of the hydrogenase 2 enzyme, composed of HybA, B, C, and O subunits; Derived by automated computational analysis using gene prediction method: Protein Homology. (392 aa)
KSB60600.1Hydrogenase 2 large subunit; Involved in hydrogen uptake; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. (567 aa)
hypAHydrogenase nickel incorporation protein; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. (113 aa)
KSB61297.1DNA repair protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (391 aa)
KSB61294.1Pyridine nucleotide-disulfide oxidoreductase; Involved in disulfide oxidoreductase activity and electron transport; Derived by automated computational analysis using gene prediction method: Protein Homology. (441 aa)
fimYFimbriae Y protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (240 aa)
dnaQDNA polymerase III subunit epsilon; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease. (243 aa)
KSB63058.1Glutamine amidotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (255 aa)
dinBDNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. (351 aa)
KSB63043.1Exodeoxyribonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. (971 aa)
KSB63015.1Terminase; Derived by automated computational analysis using gene prediction method: Protein Homology. (472 aa)
KSB62973.1Response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (213 aa)
KSB62918.1Peroxiredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. (200 aa)
ribH6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family. (156 aa)
nusBTranscription antiterminator NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. (139 aa)
xseBExodeoxyribonuclease VII small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. (80 aa)
KSB62896.1DMSO reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (777 aa)
KSB63106.14Fe-4S ferredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. (172 aa)
KSB62895.1Dimethyl sulfoxide reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (262 aa)
cyoDCytochrome o ubiquinol oxidase subunit IV; Derived by automated computational analysis using gene prediction method: Protein Homology. (109 aa)
cyoCCytochrome o ubiquinol oxidase subunit III; Derived by automated computational analysis using gene prediction method: Protein Homology. (204 aa)
clpXClp protease ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. (423 aa)
KSB62871.1Cysteine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (350 aa)
dnaXDNA polymerase III subunit gamma/tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (642 aa)
cysKCysteine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the cysteine synthase/cystathionine beta- synthase family. (323 aa)
cysMCysteine synthase; Catalyzes the formation of cysteine from 3-O-acetyl-L-serine and hydrogen sulfide; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the cysteine synthase/cystathionine beta- synthase family. (316 aa)
eutCEthanolamine ammonia-lyase; Catalyzes the formation of acetaldehyde from ethanolamine; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the EutC family. (298 aa)
KSB63942.1Ethanolamine ammonia-lyase; With EutC catalyzes the formation of acetaldehyde and ammonia from ethanolamine; Derived by automated computational analysis using gene prediction method: Protein Homology. (453 aa)
glySHypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (689 aa)
glyQglycyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (303 aa)
cysECatalyzes the O-acetylation of serine; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the transferase hexapeptide repeat family. (273 aa)
gpsAGlycerol-3-phosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (339 aa)
radCHypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0758 family. YicR subfamily. (221 aa)
coaBCBifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (407 aa)
rphRibonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. (238 aa)
rpoZDNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. (91 aa)
recGATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. (693 aa)
ilvNAcetolactate synthase 1 regulatory subunit; With IlvB catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (96 aa)
KSB63807.1Acetolactate synthase catalytic subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (562 aa)
KSB63764.1Ribonucleotide-diphosphate reductase subunit alpha; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (761 aa)
KSB63763.1Ribonucleotide-diphosphate reductase subunit beta; B2 or R2 protein; type 1a enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdA; Derived by automated computational analysis using gene prediction method: Protein Homology. (376 aa)
glpAGlycerol-3-phosphate dehydrogenase; Anaerobic, catalyzes the conversion of glycerol 3-phosphate to dihydroxyacetone using fumarate or nitrate as electron acceptor; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. (542 aa)
glpBGlycerol-3-phosphate dehydrogenase; Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor. (419 aa)
nuoNNADH:ubiquinone oxidoreductase subunit N; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 2 family. (485 aa)
KSB63732.1NADH:ubiquinone oxidoreductase subunit M; Derived by automated computational analysis using gene prediction method: Protein Homology. (509 aa)
KSB63731.1NADH:ubiquinone oxidoreductase subunit L; Catalyzes the transfer of electrons from NADH to ubiquinone; Derived by automated computational analysis using gene prediction method: Protein Homology. (613 aa)
nuoKNADH:ubiquinone oxidoreductase subunit K; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 4L family. (100 aa)
nuoJNADH:ubiquinone oxidoreductase subunit J; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (184 aa)
nuoINADH dehydrogenase; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (180 aa)
nuoHNADH:ubiquinone oxidoreductase; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone. (325 aa)
KSB63726.1NADH dehydrogenase; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. Belongs to the complex I 75 kDa subunit family. (908 aa)
nuoFNADH dehydrogenase; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Belongs to the complex I 51 kDa subunit family. (445 aa)
nuoENADH dehydrogenase; Catalyzes the transfer of electrons from NADH to quinone; Derived by automated computational analysis using gene prediction method: Protein Homology. (166 aa)
nuoCNADH:ubiquinone oxidoreductase; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the C-terminal section; belongs to the complex I 49 kDa subunit family. (600 aa)
nuoBNADH dehydrogenase; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (220 aa)
nuoANADH:ubiquinone oxidoreductase subunit A; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 3 family. (147 aa)
KSB63715.1Phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (232 aa)
accDacetyl-CoA carboxylase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (304 aa)
SBOV24751Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (108 aa)
recDExonuclease V subunit alpha; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Hol [...] (611 aa)
recBExonuclease V subunit beta; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holo [...] (1181 aa)
recCExonuclease V subunit gamma; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Hol [...] (1123 aa)
xerDRecombinase XerD; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Binds cooperatively to specific DNA consensus sequences that are separated from XerC binding sites by a short central region, forming the heterotetrameric XerC-XerD complex that recombines DNA substrates. The complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. In the complex XerD specifically exchanges the bottom [...] (298 aa)
gcvPGlycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (957 aa)
gcvHGlycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (129 aa)
gcvTGlycine cleavage system protein T; The glycine cleavage system catalyzes the degradation of glycine. (364 aa)
trmBtRNA (guanine-N7)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family. (239 aa)
KSB64427.1Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (174 aa)
KSB65782.1Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (174 aa)
nikCPeptide ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (270 aa)
KSB65772.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (215 aa)
KSB65722.1Endonuclease; 3' incision activity; acts with UvrC; Derived by automated computational analysis using gene prediction method: Protein Homology. (293 aa)
pheSphenylalanyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. (327 aa)
pheTphenylalanine--tRNA ligase; Catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. (795 aa)
sufAFunctions as a scaffold on which iron-sulfur clusters ([2Fe-2S]; [4Fe-4S]) are assembled; forms a homodimer; similar to IscA protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HesB/IscA family. (122 aa)
KSB65671.1Pyruvate kinase; Catalyzes the formation of phosphoenolpyruvate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology. (470 aa)
KSB65561.1Dimethyl sulfoxide reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (285 aa)
dmsB-2Dimethyl sulfoxide reductase; Oxidoreductase, Fe-S subunit; terminal electron transfer protein for the reduction of DMSO; Derived by automated computational analysis using gene prediction method: Protein Homology. (205 aa)
KSB65558.1Dimethyl sulfoxide reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (812 aa)
KSB65555.1Spermidine acetyltransferase; Catalyzes the formation of N(1)- and N(8)-acetylspermidine from spermidine; Derived by automated computational analysis using gene prediction method: Protein Homology. (186 aa)
hypA-3Hypothetical protein; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. (113 aa)
cybHNi/Fe hydrogenase 1 b-type cytochrome subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (247 aa)
hyaA2Uptake hydrogenase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (367 aa)
treZMalto-oligosyltrehalose trehalohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (594 aa)
KSB65492.1Formate dehydrogenase; Cytochrome b556(FDO) component; heme containing; Derived by automated computational analysis using gene prediction method: Protein Homology. (218 aa)
fdnHFormate dehydrogenase; The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers. (294 aa)
fdnGFormate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (803 aa)
KSB65489.1Sulfate ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (195 aa)
narZNitrate reductase; With NarYV catalyzes the reduction of nitrate; the beta subunit is an iron sulfur cluster containing electron transfer subunit; one of 3 nitrate reductases in E. coli; expression of nitrate reductase Z is not dependent on nitrate levels; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (1246 aa)
narHNitrate reductase; With NarGJI catalyzes the reduction of nitrate; the beta subunit is an iron sulfur cluster containing electron transfer subunit; one of 3 nitrate reductases in E. coli and in E. coli is expressed when nitrate levels are high; Derived by automated computational analysis using gene prediction method: Protein Homology. (514 aa)
nifJPyruvate-flavodoxin oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1174 aa)
pgmBBeta-phosphoglucomutase; Catalyzes the interconversion of beta-D-glucose 6-phosphate to beta-D-glucose 1-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. (219 aa)
KSB65786.1Transposase; Derived by automated computational analysis using gene prediction method: Protein Homology. (125 aa)
accAacetyl-CoA carboxylase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (319 aa)
dnaEDNA polymerase III subunit alpha; Catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1160 aa)
dgtDeoxyguanosinetriphosphate triphosphohydrolase; dGTPase preferentially hydrolyzes dGTP over the other canonical NTPs; Belongs to the dGTPase family. Type 1 subfamily. (505 aa)
KSB66643.12-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Catalyzes the formation of 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine and ATP; Derived by automated computational analysis using gene prediction method: Protein Homology. (159 aa)
lpdAE3 component of pyruvate and 2-oxoglutarate dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide; Derived by automated computational analysis using gene prediction method: Protein Homology. (474 aa)
aceFPyruvate dehydrogenase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (629 aa)
aceEPyruvate dehydrogenase; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (887 aa)
guaCGuanosine 5'-monophosphate oxidoreductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. (347 aa)
ilvHAcetolactate synthase 3 regulatory subunit; With IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (163 aa)
KSB66562.1Acetolactate synthase 3 catalytic subunit; Catalyzes the formation of 2-acetolactate from pyruvate, leucine sensitive; Derived by automated computational analysis using gene prediction method: Protein Homology. (574 aa)
leuCIsopropylmalate isomerase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (466 aa)
leuDIsopropylmalate isomerase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (201 aa)
KSB66542.1Has polymerase, DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95#C; Derived by automated computational analysis using gene prediction method: Protein Homology. (783 aa)
carBCarbamoyl phosphate synthase large subunit; Four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; Derived by automated computational analysis using gene prediction method: Protein Homology. (1074 aa)
carACarbamoyl phosphate synthase small subunit; Catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; Derived by automated computational analysis using gene prediction method: Protein Homology. (382 aa)
nadRTranscriptional regulator; Catalyzes the formation of NAD(+) from nicotinamide ribonucleotide; catalyzes the formation of nicotinamide mononucleotide from nicotinamide riboside; also has a regulatory function; Derived by automated computational analysis using gene prediction method: Protein Homology. (410 aa)
rimIRibosomal-protein-alanine acetyltransferase; Acetylates the N-terminal alanine of ribosomal protein S18. (148 aa)
holDDNA polymerase III subunit psi; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is unknown. (145 aa)
KSB66400.1DEAD/DEAH box helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. (809 aa)
KSB66399.1Restriction endonuclease subunit M; Derived by automated computational analysis using gene prediction method: Protein Homology. (489 aa)
KSB66398.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (584 aa)
KSB66349.1DNA polymerase III subunit chi; Binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB; Derived by automated computational analysis using gene prediction method: Protein Homology. (147 aa)
argF-2Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. (334 aa)
argFOrnithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. (334 aa)
pyrBAspartate carbamoyltransferase catalytic subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (311 aa)
pyrIAspartate carbamoyltransferase regulatory subunit; Involved in allosteric regulation of aspartate carbamoyltransferase. (153 aa)
pmbAPeptidase PmbA; Protease involved in proteolytic processing of the antibiotic Microcin B17 and in sensitivity to the DNA gyrase inhibitor LetD; Derived by automated computational analysis using gene prediction method: Protein Homology. (450 aa)
KSB66196.1Spore gernimation protein GerE; Derived by automated computational analysis using gene prediction method: Protein Homology. (90 aa)
KSB66191.1Dimethyl sulfoxide reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (257 aa)
dmsB4Fe-4S ferredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. (208 aa)
KSB66189.1Dimethyl sulfoxide reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (809 aa)
dcuRResponse regulator in two-component regulatory system with DcuS; phosphorylated DcuR activates transcription of genes involved in anaerobic fumarate respiration; Derived by automated computational analysis using gene prediction method: Protein Homology. (239 aa)
phnGPhosphonate C-P lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (150 aa)
phnHCarbon-phosphorus lyase complex subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (198 aa)
KSB66167.1Carbon-phosphorus lyase complex subunit PhnI; Required for the use of phosphonate and phosphite; Derived by automated computational analysis using gene prediction method: Protein Homology. (355 aa)
KSB66166.1Carbon-phosphorus lyase complex subunit PhnJ; Catalyzes the breakage of the C-P bond in alpha-D-ribose 1- methylphosphonate 5-phosphate (PRPn) forming alpha-D-ribose. Belongs to the PhnJ family. (282 aa)
phnKPhosphonate C-P lyase system protein PhnK; Derived by automated computational analysis using gene prediction method: Protein Homology. (252 aa)
phnLPhosphonate ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (226 aa)
KSB66155.1Spermidine/putrescine ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (139 aa)
uvrAExcinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (941 aa)
rpoADNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (329 aa)
tusBSulfur relay protein TusB; Part of a sulfur-relay system required for 2-thiolation of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. (95 aa)
tusCSulfur relay protein TusC; Part of a sulfur-relay system required for 2-thiolation of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. (118 aa)
tusDSulfur relay protein TusD; Part of a sulfur-relay system required for 2-thiolation of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE. (128 aa)
mdcEMalonate decarboxylase subunit gamma; Derived by automated computational analysis using gene prediction method: Protein Homology. (266 aa)
KSB65991.1The beta subunit catalyzes the decarboxylation of the malonyl moiety on coenzyme A; Derived by automated computational analysis using gene prediction method: Protein Homology. (277 aa)
glpDGlycerol-3-phosphate dehydrogenase; In Escherichia coli this homodimeric enzyme is expressed under aerobic conditions; anaerobic expression is repressed by the arcAB system; converts sn-glycerol-3-phosphate and ubiquinone-8 to dihydroxy acetone phosphate and ubiquinol-8; associates with the cytoplasmic membrane; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. (502 aa)
glgCGlucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc. (431 aa)
tusASulfur transfer protein SirA; Sulfur carrier protein involved in sulfur trafficking in the cell. Part of a sulfur-relay system required for 2-thiolation during synthesis of 2-thiouridine of the modified wobble base 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) in tRNA. Interacts with IscS and stimulates its cysteine desulfurase activity. Accepts an activated sulfur from IscS, which is then transferred to TusD, and thus determines the direction of sulfur flow from IscS to 2-thiouridine formation. Also appears to be involved in sulfur transfer for the biosynthesis of molybdopterin. (81 aa)
KSB65875.1Pyridine nucleotide-disulfide oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (400 aa)
KSB67081.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (230 aa)
KSB67072.1Dimethyl sulfoxide reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (287 aa)
KSB67071.1Dimethyl sulfoxide reductase; Oxidoreductase, Fe-S subunit; terminal electron transfer protein for the reduction of DMSO; Derived by automated computational analysis using gene prediction method: Protein Homology. (205 aa)
KSB67070.1Dimethyl sulfoxide reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (814 aa)
KSB67064.1Thioredoxin reductase; Catalyzes the transfer of electrons from NADPH to thioredoxin; FAD/NAD(P) binding; Derived by automated computational analysis using gene prediction method: Protein Homology. (322 aa)
KSB67046.1HCP oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (322 aa)
ybjQHypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0145 family. (107 aa)
moeBMolybdopterin-synthase adenylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (249 aa)
moaEMolybdenum cofactor biosynthesis protein MoaE; Catalyzes the conversion of molybdopterin precursor Z into molybdopterin; Derived by automated computational analysis using gene prediction method: Protein Homology. (150 aa)
moaDMolybdopterin synthase small subunit; Catalyzes the conversion of molybdopterin precursor Z into molybdopterin; Derived by automated computational analysis using gene prediction method: Protein Homology. (81 aa)
uvrBExcinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] (672 aa)
sucDsuccinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (289 aa)
sucCsuccinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (388 aa)
KSB66905.1Dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (402 aa)
sucA2-oxoglutarate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (933 aa)
sdhAPart of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (588 aa)
sdhCSuccinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (134 aa)
KSB66891.1DNA recombinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (188 aa)
holADNA polymerase III subunit delta; Required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA; Derived by automated computational analysis using gene prediction method: Protein Homology. (343 aa)
dpiATwo-component response regulator DpiA; Regulates the expression of citrate fermentation genes; Derived by automated computational analysis using gene prediction method: Protein Homology. (226 aa)
KSB66803.1Hydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (255 aa)
KSB66801.1DMSO reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (759 aa)
ahpFAlkyl hydroperoxide reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (521 aa)
ahpCAlkyl hydroperoxide reductase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily. (187 aa)
Your Current Organism:
Salmonella enterica salamae
NCBI taxonomy Id: 1243604
Other names: S. enterica subsp. salamae serovar 56:z10:e,n,x str. 1369-73, Salmonella enterica subsp. salamae serovar 56:z10:e,n,x str. 1369-73, Salmonella enterica subsp. salamae serovar 56:z10:enx str. SA20011914
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