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S58_02100 S58_02100 S58_03040 S58_03040 S58_07840 S58_07840 S58_08050 S58_08050 S58_08070 S58_08070 S58_09210 S58_09210 S58_09570 S58_09570 ispH ispH S58_11190 S58_11190 S58_11720 S58_11720 S58_13410 S58_13410 S58_13580 S58_13580 S58_19200 S58_19200 S58_19830 S58_19830 S58_19840 S58_19840 S58_19850 S58_19850 S58_19860 S58_19860 S58_19870 S58_19870 S58_24390 S58_24390 cobT cobT cobC cobC cobS cobS S58_27760 S58_27760 cobD cobD cobQ cobQ S58_27790 S58_27790 S58_27800 S58_27800 S58_27810 S58_27810 cobW cobW cobN cobN cobG cobG S58_27850 S58_27850 S58_27860 S58_27860 S58_27870 S58_27870 S58_27880 S58_27880 S58_27890 S58_27890 cobE cobE S58_27910 S58_27910 cbiD cbiD cobB-2 cobB-2 BluB BluB S58_30930 S58_30930 S58_31050 S58_31050 S58_32140 S58_32140 S58_33110 S58_33110 S58_34560 S58_34560 dxr dxr S58_36080 S58_36080 S58_37560 S58_37560 ispDF ispDF S58_43350 S58_43350 S58_45630 S58_45630 S58_49860 S58_49860 ispH-2 ispH-2 S58_49880 S58_49880 S58_49890 S58_49890 S58_49900 S58_49900 S58_49910 S58_49910 S58_49920 S58_49920 S58_49930 S58_49930 S58_49960 S58_49960 S58_51160 S58_51160 S58_51800 S58_51800 bioD bioD S58_51820 S58_51820 bioB bioB S58_52280 S58_52280 S58_53600 S58_53600 xseB xseB dxs dxs S58_53760 S58_53760 S58_55090 S58_55090 ispE ispE hemF hemF hemE hemE S58_56830 S58_56830 S58_56940 S58_56940 S58_56950 S58_56950 S58_58850 S58_58850 S58_58860 S58_58860 S58_58870 S58_58870 S58_58880 S58_58880 acsF acsF S58_58900 S58_58900 S58_58910 S58_58910 S58_58920 S58_58920 S58_58930 S58_58930 S58_58940 S58_58940 S58_58950 S58_58950 bchL bchL S58_58970 S58_58970 bchB bchB bchN bchN S58_59000 S58_59000 S58_59010 S58_59010 S58_59020 S58_59020 S58_59030 S58_59030 S58_59040 S58_59040 S58_59050 S58_59050 S58_59060 S58_59060 S58_59080 S58_59080 S58_59090 S58_59090 S58_59110 S58_59110 S58_59120 S58_59120 S58_59130 S58_59130 S58_59140 S58_59140 S58_59150 S58_59150 S58_59160 S58_59160 S58_59170 S58_59170 S58_59180 S58_59180 S58_59190 S58_59190 S58_59200 S58_59200 S58_59210 S58_59210 S58_59220 S58_59220 S58_59230 S58_59230 S58_59250 S58_59250 S58_59260 S58_59260 S58_59270 S58_59270 S58_59280 S58_59280 S58_59290 S58_59290 S58_59300 S58_59300 S58_60380 S58_60380 S58_62300 S58_62300 xseA xseA hemH hemH S58_64230 S58_64230 S58_67930 S58_67930 S58_68120 S58_68120 S58_68200 S58_68200 S58_70210 S58_70210 S58_70220 S58_70220 S58_70690 S58_70690 S58_70880 S58_70880 ispG ispG S58_72670 S58_72670
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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S58_02100Conserved membrane hypothetical protein. (140 aa)
S58_03040uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. (245 aa)
S58_078405-aminolevulinic acid synthase. (409 aa)
S58_08050Conserved hypothetical protein. (427 aa)
S58_08070Hypothetical protein. (212 aa)
S58_09210Putative AtrB glutamate-1-semialdehyde 2,1-aminomutase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (459 aa)
S58_09570Hypothetical protein. (252 aa)
ispH4-hydroxy-3-methylbut-2-enyl diphosphate reductase 1; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (322 aa)
S58_11190Putative putative ATP/cob(I)alamin adenosyltransferase; Belongs to the Cob(I)alamin adenosyltransferase family. (190 aa)
S58_11720Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. (476 aa)
S58_13410Oxygen-independent coproporphyrinogen III oxidase; Belongs to the anaerobic coproporphyrinogen-III oxidase family. (450 aa)
S58_13580S-adenosyl-L-methionine-dependent methyltransferase. (234 aa)
S58_19200Aminotransferase. (556 aa)
S58_19830Conserved membrane hypothetical protein. (207 aa)
S58_19840Putative NAD dependent epimerase/dehydratase family protein. (341 aa)
S58_19850Conserved membrane hypothetical protein. (183 aa)
S58_19860Putative outer membrane protein. (227 aa)
S58_19870Signal peptide. (138 aa)
S58_24390Putative uroporphyrinogen-III synthase. (280 aa)
cobTNicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). (351 aa)
cobCPutative anaerobic pathway of cobalamin biosynthesis CobC. (197 aa)
cobSCobalamin synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. (239 aa)
S58_27760Putative threonine-phosphate decarboxylase. (343 aa)
cobDAnaerobic pathway of cobalamin biosynthesis CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. (323 aa)
cobQCobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. (497 aa)
S58_27790cob(I)yrinic acid a,c-diamide adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. (204 aa)
S58_27800Adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. (178 aa)
S58_27810Conserved hypothetical protein. (119 aa)
cobWCobalamin synthesis protein CobW. (345 aa)
cobNPutative cobaltochelatase CobN. (1140 aa)
cobGPutative precorrin-3B synthase CobG. (426 aa)
S58_27850precorrin-8X methylmutase. (210 aa)
S58_27860Precorrin-2 C(20)-methyltransferase; Belongs to the precorrin methyltransferase family. (252 aa)
S58_27870Precorrin-3 methyltransferase. (255 aa)
S58_27880precorrin-6A reductase. (257 aa)
S58_27890precorrin-6Y C(5,15)-methyltransferase. (411 aa)
cobEPutative CobE protein. (132 aa)
S58_27910Precorrin-4 C(11)-methyltransferase; Belongs to the precorrin methyltransferase family. (253 aa)
cbiDcobalt-precorrin-6A synthase; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. (376 aa)
cobB-2Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. (446 aa)
BluBPutative Cob(II)yrinic acid a,c-diamide reductase BluB. (218 aa)
S58_309305-aminolevulinate synthase. (425 aa)
S58_31050Exported hypothetical protein. (168 aa)
S58_32140Isochorismatase. (187 aa)
S58_33110Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. (353 aa)
S58_34560UDP pyrophosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. (252 aa)
dxr1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (407 aa)
S58_36080Putative phytoene synthase. (287 aa)
S58_375605-aminolevulinate synthase. (409 aa)
ispDF2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF). (393 aa)
S58_43350Conserved hypothetical protein. (140 aa)
S58_45630Putative phosphoglycerate mutase family protein. (218 aa)
S58_49860Putative protein export membrane protein. (862 aa)
ispH-24-hydroxy-3-methylbut-2-enyl diphosphate reductase 2; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (308 aa)
S58_49880Hypothetical protein. (382 aa)
S58_49890Putative nucleoside phosphorylase. (250 aa)
S58_49900Putative phytoene dehydrogenase. (416 aa)
S58_49910Putative phytoene synthase. (279 aa)
S58_49920Phytoene synthase. (292 aa)
S58_49930Conserved exported hypothetical protein. (77 aa)
S58_49960Conserved hypothetical protein. (528 aa)
S58_51160Conserved hypothetical protein. (275 aa)
S58_518007,8-diaminopelargonic acid synthetase, PLP-dependent; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (421 aa)
bioDDithiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. (210 aa)
S58_518208-amino-7-oxononanoate synthase. (381 aa)
bioBBiotin synthetase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (334 aa)
S58_52280Hypothetical protein. (494 aa)
S58_53600Putative monomeric sarcosine oxidase. (397 aa)
xseBExodeoxyribonuclease small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. (83 aa)
dxs1-deoxy-D-xylulose 5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (641 aa)
S58_53760Phosphoglycerate mutase. (199 aa)
S58_55090Octaprenyl diphosphate synthase; Belongs to the FPP/GGPP synthase family. (340 aa)
ispE4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (300 aa)
hemFCoproporphyrinogen III oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX. (295 aa)
hemEUroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. (348 aa)
S58_56830Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (325 aa)
S58_56940Putative methyltransferase. (239 aa)
S58_56950Conserved exported hypothetical protein. (103 aa)
S58_588504-vinyl protochlorophyllide reductase. (216 aa)
S58_58860Mg-protoporphyrin IX monomethyl ester oxidative cyclase 66kD subunit. (531 aa)
S58_588705-aminolevulinate synthase. (403 aa)
S58_58880Hypothetical protein. (341 aa)
acsFMagnesium-protoporphyrin IX monomethyl ester cyclase; Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME); Belongs to the AcsF family. (353 aa)
S58_58900Hypothetical protein. (101 aa)
S58_58910Conserved hypothetical protein. (155 aa)
S58_58920Conserved hypothetical protein. (206 aa)
S58_58930Reaction center protein H chain. (260 aa)
S58_58940Photosynthetic complex (LH1) assembly protein LhaA, Major Facilitator Superfamily (MFS) transporter. (476 aa)
S58_58950Mg-protoporphyrin IX methyl transferase. (233 aa)
bchLProtochlorophyllide reductase iron-sulfur ATP-binding protein; Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The L component serves as a unique electron donor to the NB-component of the complex, and binds Mg-ATP. (301 aa)
S58_58970Magnesium chelatase subunit H. (1197 aa)
bchBLight-independent protochlorophyllide reductase subunit B; Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein (BchN-BchB) is the catalytic component of the complex. (517 aa)
bchNLight-independent protochlorophyllide reductase subunit N; Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein (BchN-BchB) is the catalytic component of the complex. (428 aa)
S58_590002-vinyl bacteriochlorophyllide hydratase. (196 aa)
S58_59010Putative regulator with a cobalamin (vitamin B12)-binding domain, AerR-like. (265 aa)
S58_59020Fis family transcriptional regulator. (455 aa)
S58_59030Bacteriochlorophyll synthase 33 kDa chain. (304 aa)
S58_59040Light harvesting pigment major facilitator family (MFS) transporter, Bch2-like protein. (444 aa)
S58_59050Geranylgeranyl reductase. (403 aa)
S58_59060Conserved hypothetical protein. (87 aa)
S58_59080Transcriptional regulator PpsR2. (456 aa)
S58_59090Bacteriophytochrome. (724 aa)
S58_59110Photosynthetic reaction center subunit M; The reaction center is a membrane-bound complex that mediates the initial photochemical event in the electron transfer process of photosynthesis. (308 aa)
S58_59120Photosynthetic reaction center subunit L. (278 aa)
S58_59130Light harvesting 1 subunit alpha; Antenna complexes are light-harvesting systems, which transfer the excitation energy to the reaction centers. (62 aa)
S58_59140Light harvesting 1 subunit beta; Antenna complexes are light-harvesting systems, which transfer the excitation energy to the reaction centers. (76 aa)
S58_59150Conserved hypothetical protein. (75 aa)
S58_59160Bacteriochlorophyllide reductase Z subunit. (483 aa)
S58_59170Bacteriochlorophyllide reductase subunit 52.5 kDa chain. (515 aa)
S58_59180Bacteriochlorophyllide reductase subunit; Belongs to the NifH/BchL/ChlL family. (332 aa)
S58_591902-desacetyl-2-hydroxyethyl bacteriochlorophyllide A dehydrogenase. (313 aa)
S58_59200hydroxyneurosporene-O-methyltransferase. (381 aa)
S58_59210Geranylgeranyl pyrophosphate synthetase; Belongs to the FPP/GGPP synthase family. (289 aa)
S58_59220Hydroxyneurosporene and rhodopin dehydrogenase. (509 aa)
S58_59230Neurosporene and anhydrorhodovibrin hydratase. (270 aa)
S58_59250Phytoene synthase. (346 aa)
S58_59260Phytoene dehydrogenase. (512 aa)
S58_59270Putative Alpha/beta hydrolase, protoporphyrin IX magnesium chelatase bchO-like. (305 aa)
S58_59280Putative alpha/beta hydrolase fold. (322 aa)
S58_59290Magnesium-chelatase 60 kDa subunit. (580 aa)
S58_59300Magnesium-chelatase 38 kDa subunit; Involved in bacteriochlorophyll biosynthesis; introduces a magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX. (348 aa)
S58_603805-aminolevulinate synthase. (436 aa)
S58_62300Putative membrane protein. (139 aa)
xseAExodeoxyribonuclease VII large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. (538 aa)
hemHFerrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (355 aa)
S58_64230Squalene-hopene cyclase. (684 aa)
S58_67930Conserved hypothetical protein. (506 aa)
S58_68120Conserved hypothetical protein. (265 aa)
S58_68200uroporphyrinogen-III C-methyltransferase; Belongs to the precorrin methyltransferase family. (259 aa)
S58_70210Aerobic cobaltochelatase subunit CobT. (633 aa)
S58_70220Cobalt chelatase small subunit. (332 aa)
S58_70690Conserved hypothetical protein. (155 aa)
S58_70880Putative geranyltranstransferase; Belongs to the FPP/GGPP synthase family. (307 aa)
ispG4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (437 aa)
S58_72670UDP pyrophosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. (247 aa)
Your Current Organism:
Bradyrhizobium oligotrophicum
NCBI taxonomy Id: 1245469
Other names: Agromonas oligotrophica LMG 10732, Agromonas oligotrophica S58, B. oligotrophicum S58, Bradyrhizobium oligotrophicum S58
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