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miaB miaB S58_01470 S58_01470 nth nth yggW yggW S58_02470 S58_02470 rlmN rlmN leuC leuC S58_03920 S58_03920 S58_04010 S58_04010 S58_07920 S58_07920 S58_08550 S58_08550 ispH ispH S58_11740 S58_11740 S58_11760 S58_11760 S58_13410 S58_13410 S58_17780 S58_17780 pqqE pqqE thiC thiC S58_19240 S58_19240 S58_21070 S58_21070 S58_21610 S58_21610 soxA soxA leuC-2 leuC-2 S58_22590 S58_22590 sufB sufB nifH nifH S58_22740 S58_22740 nifB nifB S58_22870 S58_22870 S58_23100 S58_23100 phnJ phnJ S58_24080 S58_24080 S58_26740 S58_26740 S58_27080 S58_27080 S58_27090 S58_27090 cobG cobG moaA moaA S58_30590 S58_30590 nadA nadA S58_32710 S58_32710 nuoB nuoB S58_34150 S58_34150 S58_34160 S58_34160 nuoI nuoI S58_36630 S58_36630 S58_37000 S58_37000 S58_37480 S58_37480 rimO rimO S58_38390 S58_38390 lipA lipA S58_39790 S58_39790 S58_43710 S58_43710 S58_43830 S58_43830 S58_49760 S58_49760 ispH-2 ispH-2 S58_50020 S58_50020 bioB bioB S58_53690 S58_53690 S58_55120 S58_55120 S58_55130 S58_55130 S58_55250 S58_55250 S58_55480 S58_55480 S58_55510 S58_55510 queE queE S58_58410 S58_58410 S58_58550 S58_58550 hupU hupU S58_58860 S58_58860 bchL bchL bchB bchB bchN bchN S58_59180 S58_59180 S58_60280 S58_60280 S58_60370 S58_60370 napD-2 napD-2 S58_63090 S58_63090 S58_67910 S58_67910 S58_68140 S58_68140 S58_68250 S58_68250 S58_68260 S58_68260 S58_70010 S58_70010 ispG ispG
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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from curated databases
experimentally determined
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gene fusions
gene co-occurrence
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textmining
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miaBConserved hypothetical protein; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine. (473 aa)
S58_01470Conserved hypothetical protein. (345 aa)
nthEndonuclease III DNA-(apurinic or apyrimidinic site) lyase; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (290 aa)
yggWPutative oxygen-independent coproporphyrinogen III oxidase YggW; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. (385 aa)
S58_02470Succinate dehydrogenase, Fe-S protein; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (260 aa)
rlmNPutative pyruvate formate lyase activating enzyme 2; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family. (403 aa)
leuCIsopropylmalate isomerase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (468 aa)
S58_03920miaB-like tRNA modifying enzyme. (444 aa)
S58_04010Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (906 aa)
S58_07920Putative aldehyde or xanthine dehydrogenase, FAD-binding subunit. (352 aa)
S58_08550Radical SAM domain protein. (299 aa)
ispH4-hydroxy-3-methylbut-2-enyl diphosphate reductase 1; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (322 aa)
S58_11740Sulfite/ferredoxin-nitrite reductase. (551 aa)
S58_11760Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. (241 aa)
S58_13410Oxygen-independent coproporphyrinogen III oxidase; Belongs to the anaerobic coproporphyrinogen-III oxidase family. (450 aa)
S58_17780Oxydoreductase, 2Fe-2S ferredoxin like subunit. (97 aa)
pqqEPyrroloquinoline quinone biosynthesis protein PqqE; Catalyzes the cross-linking of a glutamate residue and a tyrosine residue in the PqqA protein as part of the biosynthesis of pyrroloquinoline quinone (PQQ). (398 aa)
thiCThiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. (633 aa)
S58_19240Putative xanthine dehydrogenase (YagS-like), FAD binding subunit. (338 aa)
S58_21070Molybdopterin dehydrogenase, FAD-binding protein. (306 aa)
S58_21610L-lysine 2,3-aminomutase. (438 aa)
soxASoxA protein. (98 aa)
leuC-2Isopropylmalate isomerase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (473 aa)
S58_22590Ferredoxin. (77 aa)
sufBCysteine desulfurase activator complex subunit SufB. (506 aa)
nifHNitrogenase reductase; The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein; Belongs to the NifH/BchL/ChlL family. (295 aa)
S58_22740Ferredoxin III. (95 aa)
nifBNitrogenase FeMo cofactor biosynthesis protein NifB. (520 aa)
S58_22870Ferredoxin-like protein. (74 aa)
S58_23100Nitrogenase reductase. (295 aa)
phnJPutative PhnJ protein, phosphonate metabolism; Catalyzes the breakage of the C-P bond in alpha-D-ribose 1- methylphosphonate 5-phosphate (PRPn) forming alpha-D-ribose. Belongs to the PhnJ family. (294 aa)
S58_24080Putative dimethyl sulfoxide reductase; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (709 aa)
S58_26740Fumarase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (551 aa)
S58_27080Formate dehydrogenase, alpha subunit. (959 aa)
S58_27090Formate dehydrogenase beta subunit. (518 aa)
cobGPutative precorrin-3B synthase CobG. (426 aa)
moaAMolybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (343 aa)
S58_30590Putative pyruvate ferredoxin/flavodoxin oxidoreductase. (1163 aa)
nadAQuinolinate synthetase A; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (328 aa)
S58_32710Putative uracil-DNA glycosylase. (234 aa)
nuoBNADH dehydrogenase subunit B; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (196 aa)
S58_34150NADH dehydrogenase I subunit F; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Belongs to the complex I 51 kDa subunit family. (441 aa)
S58_34160NADH dehydrogenase subunit G; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. Belongs to the complex I 75 kDa subunit family. (689 aa)
nuoINADH-quinone oxidoreductase chain I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (162 aa)
S58_36630Putative citrate utilization protein B, CitB. (372 aa)
S58_37000Cysteine desulfurase activator complex subunit SufB. (498 aa)
S58_37480Putative lysine 2,3-aminomutase. (364 aa)
rimORibosomal protein S12 methylthiotransferase; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily. (441 aa)
S58_38390Putative ferredoxin-nitrite reductase; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. (596 aa)
lipALipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (319 aa)
S58_39790Putative formate dehydrogenase (C-terminal), related to acid resistance with formate dehydrogenase/DMSO reductase, domains 1-3 and ADC-like domain; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (761 aa)
S58_43710Putative sarcosine oxidase alpha subunit. (97 aa)
S58_43830Hydrogenase expression/formation protein HypD; Belongs to the HypD family. (396 aa)
S58_49760Putative uracil-DNA glycosylase. (494 aa)
ispH-24-hydroxy-3-methylbut-2-enyl diphosphate reductase 2; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (308 aa)
S58_50020Hypothetical protein. (508 aa)
bioBBiotin synthetase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (334 aa)
S58_53690Putative RNA methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (411 aa)
S58_55120Putative electron transfer flavoprotein dehydrogenases; Accepts electrons from ETF and reduces ubiquinone. (552 aa)
S58_55130DNA polymerase. (273 aa)
S58_55250Hypothetical protein. (382 aa)
S58_55480Adenine glycosylase MutY. (67 aa)
S58_55510A/G-specific DNA-adenine glycosylase; Adenine glycosylase active on G-A mispairs. (367 aa)
queEConserved hypothetical protein, putative organic radical activating enzyme; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. (210 aa)
S58_58410Hydrogenase expression/formation protein; Belongs to the HypD family. (375 aa)
S58_58550Uptake hydrogenase small subunit. (363 aa)
hupUUptake hydrogenase accessory protein HupU. (339 aa)
S58_58860Mg-protoporphyrin IX monomethyl ester oxidative cyclase 66kD subunit. (531 aa)
bchLProtochlorophyllide reductase iron-sulfur ATP-binding protein; Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The L component serves as a unique electron donor to the NB-component of the complex, and binds Mg-ATP. (301 aa)
bchBLight-independent protochlorophyllide reductase subunit B; Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein (BchN-BchB) is the catalytic component of the complex. (517 aa)
bchNLight-independent protochlorophyllide reductase subunit N; Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein (BchN-BchB) is the catalytic component of the complex. (428 aa)
S58_59180Bacteriochlorophyllide reductase subunit; Belongs to the NifH/BchL/ChlL family. (332 aa)
S58_60280Hypothetical protein. (588 aa)
S58_60370Fe-S oxidoreductase. (512 aa)
napD-2Nitrate reductase catalytic subunit; Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite. (834 aa)
S58_63090Glycolate oxidase iron-sulfur subunit GlcF. (444 aa)
S58_67910Hypothetical protein. (675 aa)
S58_68140Hypothetical protein. (402 aa)
S58_68250Protease. (296 aa)
S58_68260Peptidase. (325 aa)
S58_70010Ferredoxin II; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. (112 aa)
ispG4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (437 aa)
Your Current Organism:
Bradyrhizobium oligotrophicum
NCBI taxonomy Id: 1245469
Other names: Agromonas oligotrophica LMG 10732, Agromonas oligotrophica S58, B. oligotrophicum S58, Bradyrhizobium oligotrophicum S58
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