(5 nodes) L-phosphoserine phosphatase activity, and Serine dehydratase beta chain network (Pseudomonas resinovorans NBRC106553)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	sdaA	L-serine dehydratase; Belongs to the iron-sulfur dependent L-serine dehydratase family. (458 aa)
	thrH	Phosphoserine:homoserine phosphotransferase. (205 aa)
	glyA-3	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (417 aa)
	sdaA-3	L-serine dehydratase; Belongs to the iron-sulfur dependent L-serine dehydratase family. (458 aa)
	serB	Phosphoserine phosphatase. (404 aa)

Your Current Organism:

Pseudomonas resinovorans NBRC106553

NCBI taxonomy Id: 1245471
Other names: P. resinovorans NBRC 106553, Pseudomonas resinovorans NBRC 106553

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
glyA-3	sdaA	PCA10_43460	PCA10_04030	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	L-serine dehydratase; Belongs to the iron-sulfur dependent L-serine dehydratase family.	0.938
glyA-3	sdaA-3	PCA10_43460	PCA10_43470	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	L-serine dehydratase; Belongs to the iron-sulfur dependent L-serine dehydratase family.	0.982
glyA-3	serB	PCA10_43460	PCA10_51980	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	Phosphoserine phosphatase.	0.942
glyA-3	thrH	PCA10_43460	PCA10_32870	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	Phosphoserine:homoserine phosphotransferase.	0.916
sdaA	glyA-3	PCA10_04030	PCA10_43460	L-serine dehydratase; Belongs to the iron-sulfur dependent L-serine dehydratase family.	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	0.938
sdaA	sdaA-3	PCA10_04030	PCA10_43470	L-serine dehydratase; Belongs to the iron-sulfur dependent L-serine dehydratase family.	L-serine dehydratase; Belongs to the iron-sulfur dependent L-serine dehydratase family.	0.902
sdaA	serB	PCA10_04030	PCA10_51980	L-serine dehydratase; Belongs to the iron-sulfur dependent L-serine dehydratase family.	Phosphoserine phosphatase.	0.933
sdaA	thrH	PCA10_04030	PCA10_32870	L-serine dehydratase; Belongs to the iron-sulfur dependent L-serine dehydratase family.	Phosphoserine:homoserine phosphotransferase.	0.907
sdaA-3	glyA-3	PCA10_43470	PCA10_43460	L-serine dehydratase; Belongs to the iron-sulfur dependent L-serine dehydratase family.	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	0.982
sdaA-3	sdaA	PCA10_43470	PCA10_04030	L-serine dehydratase; Belongs to the iron-sulfur dependent L-serine dehydratase family.	L-serine dehydratase; Belongs to the iron-sulfur dependent L-serine dehydratase family.	0.902
sdaA-3	serB	PCA10_43470	PCA10_51980	L-serine dehydratase; Belongs to the iron-sulfur dependent L-serine dehydratase family.	Phosphoserine phosphatase.	0.933
sdaA-3	thrH	PCA10_43470	PCA10_32870	L-serine dehydratase; Belongs to the iron-sulfur dependent L-serine dehydratase family.	Phosphoserine:homoserine phosphotransferase.	0.907
serB	glyA-3	PCA10_51980	PCA10_43460	Phosphoserine phosphatase.	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	0.942
serB	sdaA	PCA10_51980	PCA10_04030	Phosphoserine phosphatase.	L-serine dehydratase; Belongs to the iron-sulfur dependent L-serine dehydratase family.	0.933
serB	sdaA-3	PCA10_51980	PCA10_43470	Phosphoserine phosphatase.	L-serine dehydratase; Belongs to the iron-sulfur dependent L-serine dehydratase family.	0.933
serB	thrH	PCA10_51980	PCA10_32870	Phosphoserine phosphatase.	Phosphoserine:homoserine phosphotransferase.	0.942
thrH	glyA-3	PCA10_32870	PCA10_43460	Phosphoserine:homoserine phosphotransferase.	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	0.916
thrH	sdaA	PCA10_32870	PCA10_04030	Phosphoserine:homoserine phosphotransferase.	L-serine dehydratase; Belongs to the iron-sulfur dependent L-serine dehydratase family.	0.907
thrH	sdaA-3	PCA10_32870	PCA10_43470	Phosphoserine:homoserine phosphotransferase.	L-serine dehydratase; Belongs to the iron-sulfur dependent L-serine dehydratase family.	0.907
thrH	serB	PCA10_32870	PCA10_51980	Phosphoserine:homoserine phosphotransferase.	Phosphoserine phosphatase.	0.942