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puuA-4 puuA-4 spuI spuI spuB spuB gshB gshB bioD bioD puuA puuA birA birA mpl mpl nadE-2 nadE-2 gatB gatB gatA gatA gatC gatC murE murE murF murF murD murD murC murC ddlB ddlB guaA guaA purL purL asnB asnB BAN47160.1 BAN47160.1 puuA-2 puuA-2 nadE nadE pncB pncB BAN47375.1 BAN47375.1 BAN47421.1 BAN47421.1 cobB-2 cobB-2 folC folC BAN47984.1 BAN47984.1 BAN48089.1 BAN48089.1 panC panC BAN48987.1 BAN48987.1 BAN49113.1 BAN49113.1 BAN49362.1 BAN49362.1 BAN49459.1 BAN49459.1 puuA-3 puuA-3 BAN49788.1 BAN49788.1 BAN49878.1 BAN49878.1 BAN50041.1 BAN50041.1 argG argG purC purC queC queC purM purM pyrG pyrG tilS tilS BAN50527.1 BAN50527.1 panC-2 panC-2 carB carB carA carA BAN50691.1 BAN50691.1 accC accC purD purD BAN50838.1 BAN50838.1 BAN50893.1 BAN50893.1 purA purA glnA glnA rimK rimK gshA gshA BAN51178.1 BAN51178.1 coaBC coaBC purK purK pycA pycA
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
puuA-4Gamma-glutamylputrescine synthetase; Belongs to the glutamine synthetase family. (457 aa)
spuIGamma-glutamylpolyamine synthetase SpuI; Belongs to the glutamine synthetase family. (423 aa)
spuBGamma-glutamylpolyamine synthetase SpuB; Belongs to the glutamine synthetase family. (452 aa)
gshBGlutathione synthetase; Belongs to the prokaryotic GSH synthase family. (323 aa)
bioDATP-dependent dethiobiotin synthetase BioD; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. (231 aa)
puuAGamma-glutamylputrescine synthetase; Belongs to the glutamine synthetase family. (450 aa)
birABiotin protein ligase/biotin operon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. (333 aa)
mplUDP-N-acetylmuramate--L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase; Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl- meso-diaminopimelate by linking it to UDP-N-acetylmuramate. Belongs to the MurCDEF family. Mpl subfamily. (450 aa)
nadE-2Putative glutamine-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (543 aa)
gatBaspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily. (481 aa)
gatAglutamyl-tRNA(Gln) amidotransferase subunit A; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). (483 aa)
gatCaspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family. (95 aa)
murEUDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. (487 aa)
murFUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. (454 aa)
murDUDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (446 aa)
murCUDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. (486 aa)
ddlBD-alanine--D-alanine ligase B; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. (315 aa)
guaAGMP synthase; Catalyzes the synthesis of GMP from XMP. (525 aa)
purLPhosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. (1298 aa)
asnBAsparagine synthetase. (589 aa)
BAN47160.1Putative glutamine synthetase. (444 aa)
puuA-2Gamma-glutamylputrescine synthetase; Belongs to the glutamine synthetase family. (454 aa)
nadENH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family. (276 aa)
pncBNicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. (401 aa)
BAN47375.1Hypothetical protein. (271 aa)
BAN47421.1Hypothetical protein. (198 aa)
cobB-2Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. (429 aa)
folCFolylpolyglutamate synthetase; Belongs to the folylpolyglutamate synthase family. (428 aa)
BAN47984.1Hypothetical protein. (469 aa)
BAN48089.1Putative carboxylate-amine ligase; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily. (379 aa)
panCPantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (283 aa)
BAN48987.1Putative glutamate--ammonia ligase; Belongs to the glutamine synthetase family. (457 aa)
BAN49113.1Putative amidase. (570 aa)
BAN49362.1Hypothetical protein. (422 aa)
BAN49459.1Hypothetical protein. (328 aa)
puuA-3Gamma-glutamylputrescine synthetase; Belongs to the glutamine synthetase family. (452 aa)
BAN49788.1Putative glutamate--ammonia ligase; Belongs to the glutamine synthetase family. (447 aa)
BAN49878.1Hypothetical protein. (232 aa)
BAN50041.1Putative urea carboxylase. (1199 aa)
argGArgininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (405 aa)
purCPhosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. (289 aa)
queC7-cyano-7-deazaguanine synthase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. (224 aa)
purMPhosphoribosylformylglycinamidine cyclo-ligase. (352 aa)
pyrGCTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (507 aa)
tilStRNA(Ile)-lysidine synthase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. (449 aa)
BAN50527.1Hypothetical protein. (147 aa)
panC-2Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (286 aa)
carBCarbamoyl-phosphate synthase large chain; Belongs to the CarB family. (1073 aa)
carACarbamoyl-phosphate synthase small chain; Belongs to the CarA family. (378 aa)
BAN50691.1Hypothetical protein; Belongs to the glutamine synthetase family. (458 aa)
accCacetyl-CoA carboxylase biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (449 aa)
purDPhosphoribosylamine--glycine ligase; Belongs to the GARS family. (429 aa)
BAN50838.1Allophanate hydrolase. (605 aa)
BAN50893.1Hypothetical protein. (832 aa)
purAAdenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (431 aa)
glnAGlutamine synthetase. (467 aa)
rimKRibosomal protein S6 modification protein; Belongs to the RimK family. (301 aa)
gshAGlutamate--cysteine ligase; Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily. (528 aa)
BAN51178.15-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. (201 aa)
coaBCPhosphopantothenoylcysteine decarboxylase/phosphopantothenoylcysteine synthetase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (402 aa)
purKN5-carboxyaminoimidazole ribonucleotide synthase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (361 aa)
pycAPyruvate carboxylase subunit A; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (471 aa)
Your Current Organism:
Pseudomonas resinovorans NBRC106553
NCBI taxonomy Id: 1245471
Other names: P. resinovorans NBRC 106553, Pseudomonas resinovorans NBRC 106553
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