node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BAN47984.1 | BAN48089.1 | PCA10_22520 | PCA10_23570 | Hypothetical protein. | Putative carboxylate-amine ligase; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily. | 0.872 |
BAN47984.1 | BAN50893.1 | PCA10_22520 | PCA10_51610 | Hypothetical protein. | Hypothetical protein. | 0.752 |
BAN48089.1 | BAN47984.1 | PCA10_23570 | PCA10_22520 | Putative carboxylate-amine ligase; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily. | Hypothetical protein. | 0.872 |
BAN48089.1 | gshA | PCA10_23570 | PCA10_54220 | Putative carboxylate-amine ligase; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily. | Glutamate--cysteine ligase; Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily. | 0.920 |
BAN48089.1 | gshB | PCA10_23570 | PCA10_03400 | Putative carboxylate-amine ligase; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily. | Glutathione synthetase; Belongs to the prokaryotic GSH synthase family. | 0.928 |
BAN50893.1 | BAN47984.1 | PCA10_51610 | PCA10_22520 | Hypothetical protein. | Hypothetical protein. | 0.752 |
coaBC | folC | PCA10_55220 | PCA10_20160 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenoylcysteine synthetase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Folylpolyglutamate synthetase; Belongs to the folylpolyglutamate synthase family. | 0.475 |
coaBC | panC | PCA10_55220 | PCA10_27510 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenoylcysteine synthetase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.891 |
coaBC | panC-2 | PCA10_55220 | PCA10_48900 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenoylcysteine synthetase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.891 |
ddlB | mpl | PCA10_10800 | PCA10_07810 | D-alanine--D-alanine ligase B; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | UDP-N-acetylmuramate--L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase; Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl- meso-diaminopimelate by linking it to UDP-N-acetylmuramate. Belongs to the MurCDEF family. Mpl subfamily. | 0.823 |
ddlB | murC | PCA10_10800 | PCA10_10790 | D-alanine--D-alanine ligase B; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.998 |
ddlB | murD | PCA10_10800 | PCA10_10760 | D-alanine--D-alanine ligase B; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.985 |
ddlB | murE | PCA10_10800 | PCA10_10730 | D-alanine--D-alanine ligase B; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.963 |
ddlB | murF | PCA10_10800 | PCA10_10740 | D-alanine--D-alanine ligase B; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.998 |
folC | coaBC | PCA10_20160 | PCA10_55220 | Folylpolyglutamate synthetase; Belongs to the folylpolyglutamate synthase family. | Phosphopantothenoylcysteine decarboxylase/phosphopantothenoylcysteine synthetase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.475 |
folC | murF | PCA10_20160 | PCA10_10740 | Folylpolyglutamate synthetase; Belongs to the folylpolyglutamate synthase family. | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.424 |
gshA | BAN48089.1 | PCA10_54220 | PCA10_23570 | Glutamate--cysteine ligase; Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily. | Putative carboxylate-amine ligase; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily. | 0.920 |
gshA | gshB | PCA10_54220 | PCA10_03400 | Glutamate--cysteine ligase; Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily. | Glutathione synthetase; Belongs to the prokaryotic GSH synthase family. | 0.935 |
gshB | BAN48089.1 | PCA10_03400 | PCA10_23570 | Glutathione synthetase; Belongs to the prokaryotic GSH synthase family. | Putative carboxylate-amine ligase; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily. | 0.928 |
gshB | gshA | PCA10_03400 | PCA10_54220 | Glutathione synthetase; Belongs to the prokaryotic GSH synthase family. | Glutamate--cysteine ligase; Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily. | 0.935 |