STRINGSTRING
nrdJa nrdJa rdgB rdgB BAN46252.1 BAN46252.1 apaH apaH amn amn cysD cysD cysNC cysNC ndk ndk guaB guaB guaA guaA purL purL BAN46962.1 BAN46962.1 cysC cysC BAN47511.1 BAN47511.1 nrdB nrdB nrdA nrdA pyk pyk allA allA BAN47656.1 BAN47656.1 BAN47658.1 BAN47658.1 guaD guaD xdhB xdhB xdhA xdhA purF purF BAN47807.1 BAN47807.1 ppnP ppnP BAN47977.1 BAN47977.1 purB purB BAN48795.1 BAN48795.1 guaD-2 guaD-2 BAN49024.1 BAN49024.1 BAN49347.1 BAN49347.1 BAN49348.1 BAN49348.1 BAN49351.1 BAN49351.1 apt apt cyaB cyaB BAN50109.1 BAN50109.1 purC purC purM purM purN purN mazG mazG relA relA surE surE adk adk purT purT pykA pykA BAN50543.1 BAN50543.1 prs prs BAN50686.1 BAN50686.1 BAN50762.1 BAN50762.1 purH purH purD purD ureA ureA ureB ureB ureC ureC purA purA cpdA cpdA nudF nudF arcC arcC nudE nudE BAN51128.1 BAN51128.1 ppx ppx cyaA cyaA xpt xpt algC algC gmk gmk spoT spoT purK purK purE purE
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
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nrdJaRibonucleotide reductase subunit NrdJa; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. (715 aa)
rdgBdITP/XTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (197 aa)
BAN46252.1Putative hydantoin racemase. (245 aa)
apaHBis(5'-nucleosyl)-tetraphosphatase; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. (275 aa)
amnAMP nucleosidase; Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations. (490 aa)
cysDSulfate adenylyltransferase subunit 2. (305 aa)
cysNCSulfate adenylyltransferase subunit 1/adenylyl-sulfate kinase; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. (633 aa)
ndkNucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (143 aa)
guaBInosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (489 aa)
guaAGMP synthase; Catalyzes the synthesis of GMP from XMP. (525 aa)
purLPhosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. (1298 aa)
BAN46962.1Hypothetical protein. (327 aa)
cysCAdenylyl-sulfate kinase; Catalyzes the synthesis of activated sulfate. (205 aa)
BAN47511.1Hypothetical protein. (278 aa)
nrdBRibonucleoside-diphosphate reductase beta subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. (415 aa)
nrdARibonucleoside-diphosphate reductase alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (963 aa)
pykPyruvate kinase; Belongs to the pyruvate kinase family. (471 aa)
allAUreidoglycolate hydrolase; Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source. (167 aa)
BAN47656.1Hypothetical protein. (171 aa)
BAN47658.15-hydroxyisourate hydrolase; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily. (135 aa)
guaDGuanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family. (440 aa)
xdhBXanthine dehydrogenase large subunit. (798 aa)
xdhAXanthine dehydrogenase small subunit. (479 aa)
purFAmidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (501 aa)
BAN47807.1Putative deoxyguanosinetriphosphate triphosphohydrolase. (443 aa)
ppnPHypothetical protein; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions. (93 aa)
BAN47977.1Hypothetical protein. (235 aa)
purBAdenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (456 aa)
BAN48795.1Hypothetical protein. (497 aa)
guaD-2Guanine deaminase. (153 aa)
BAN49024.1Putative 5'-nucleotidase. (301 aa)
BAN49347.15-hydroxyisourate hydrolase; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily. (111 aa)
BAN49348.15-hydroxyisourate hydrolase. (100 aa)
BAN49351.1Hypothetical protein. (176 aa)
aptAdenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (182 aa)
cyaBAdenylyl cyclase CyaB. (457 aa)
BAN50109.1Hypothetical protein. (465 aa)
purCPhosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. (289 aa)
purMPhosphoribosylformylglycinamidine cyclo-ligase. (352 aa)
purNPhosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (216 aa)
mazGNucleoside triphosphate pyrophosphohydrolase. (276 aa)
relAGTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (748 aa)
surE5'-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (249 aa)
adkAdenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (215 aa)
purTPhosphoribosylglycinamide formyltransferase 2; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family. (393 aa)
pykAPyruvate kinase II; Belongs to the pyruvate kinase family. (483 aa)
BAN50543.1Putative hypoxanthine-guanine phosphoribosyltransferase. (185 aa)
prsRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (330 aa)
BAN50686.1Hypothetical protein. (225 aa)
BAN50762.1Adenine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism. (316 aa)
purHPhosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase. (535 aa)
purDPhosphoribosylamine--glycine ligase; Belongs to the GARS family. (429 aa)
ureAUrease subunit gamma; Belongs to the urease gamma subunit family. (100 aa)
ureBUrease subunit beta; Belongs to the urease beta subunit family. (101 aa)
ureCUrease subunit alpha. (566 aa)
purAAdenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (431 aa)
cpdA3',5'-cyclic AMP phosphodiesterase; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. (271 aa)
nudFADP-ribose pyrophosphatase. (205 aa)
arcCCarbamate kinase; Belongs to the carbamate kinase family. (310 aa)
nudEADP compound hydrolase. (188 aa)
BAN51128.1Putative hydrolase. (220 aa)
ppxExopolyphosphatase; Belongs to the GppA/Ppx family. (500 aa)
cyaAAdenylate cyclase. (945 aa)
xptXanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. (190 aa)
algCPhosphomannomutase/phosphoglucomutase AlgC. (864 aa)
gmkGuanylate kinase; Essential for recycling GMP and indirectly, cGMP. (206 aa)
spoT(p)ppGpp synthase/hydrolase SpoT; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (702 aa)
purKN5-carboxyaminoimidazole ribonucleotide synthase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (361 aa)
purEN5-carboxyaminoimidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (163 aa)
Your Current Organism:
Pseudomonas resinovorans NBRC106553
NCBI taxonomy Id: 1245471
Other names: P. resinovorans NBRC 106553, Pseudomonas resinovorans NBRC 106553
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