(43 nodes) Tryptophan metabolism network (Pseudomonas resinovorans NBRC106553)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	gcdH	glutaryl-CoA dehydrogenase. (393 aa)
	BAN46084.1	Putative oxidoreductase. (491 aa)
	katG	Catalase-peroxidase; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity; Belongs to the peroxidase family. Peroxidase/catalase subfamily. (716 aa)
	BAN47073.1	enoyl-CoA hydratase/isomerase family protein. (287 aa)
	BAN47075.1	Putative enoyl-CoA hydratase. (252 aa)
	BAN47078.1	Putative acetyl-CoA acyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (382 aa)
	BAN47109.1	Putative acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (400 aa)
	BAN47204.1	Putative amidase; Belongs to the amidase family. (372 aa)
	BAN47220.1	Hypothetical protein. (289 aa)
	fadB	Fatty acid oxidation complex subunit alpha; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. (715 aa)
	sucB	2-oxoglutarate dehydrogenase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (406 aa)
	lpd	Dihydrolipoyl dehydrogenase. (478 aa)
	fadA-2	3-ketoacyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (401 aa)
	fadB-2	Fatty acid oxidation complex subunit alpha. (714 aa)
	BAN48000.1	enoyl-CoA hydratase/isomerase family protein. (229 aa)
	BAN48092.1	Putative amidase. (484 aa)
	BAN48190.1	Putative catalase; Has an organic peroxide-dependent peroxidase activity. Belongs to the catalase family. (352 aa)
	lpd-2	Dihydrolipoyl dehydrogenase. (466 aa)
	BAN48508.1	enoyl-CoA hydratase/isomerase family protein. (266 aa)
	BAN48523.1	Putative acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (395 aa)
	BAN48551.1	Putative enoyl-CoA hydratase. (255 aa)
	BAN48563.1	Putative enoyl-CoA hydratase. (263 aa)
	BAN48567.1	Putative enoyl-CoA hydratase. (264 aa)
	BAN48585.1	Putative acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (395 aa)
	BAN48713.1	Putative acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (394 aa)
	BAN48753.1	Putative catalase; Has an organic peroxide-dependent peroxidase activity. Belongs to the catalase family. (331 aa)
	BAN48972.1	Putative enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (257 aa)
	BAN48974.1	acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (396 aa)
	paaF	2,3-dehydroadipyl-CoA hydratase PaaF; Belongs to the enoyl-CoA hydratase/isomerase family. (257 aa)
	BAN49113.1	Putative amidase. (570 aa)
	BAN49173.1	Putative aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (484 aa)
	BAN49209.1	Putative acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (392 aa)
	BAN49399.1	Putative enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (270 aa)
	kynU	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. (416 aa)
	kynB	Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. (213 aa)
	BAN50292.1	Putative enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (277 aa)
	BAN50403.1	Putative amidase. (494 aa)
	BAN50479.1	Putative enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (257 aa)
	BAN50521.1	acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (391 aa)
	BAN50629.1	Putative acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (392 aa)
	BAN50786.1	acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (425 aa)
	BAN50883.1	Putative aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (496 aa)
	BAN51058.1	Hypothetical protein. (431 aa)

Your Current Organism:

Pseudomonas resinovorans NBRC106553

NCBI taxonomy Id: 1245471
Other names: P. resinovorans NBRC 106553, Pseudomonas resinovorans NBRC 106553

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BAN46084.1	BAN49113.1	PCA10_03520	PCA10_33810	Putative oxidoreductase.	Putative amidase.	0.404
BAN46084.1	BAN49173.1	PCA10_03520	PCA10_34410	Putative oxidoreductase.	Putative aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	0.901
BAN46084.1	BAN50883.1	PCA10_03520	PCA10_51510	Putative oxidoreductase.	Putative aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	0.901
BAN46084.1	BAN51058.1	PCA10_03520	PCA10_53260	Putative oxidoreductase.	Hypothetical protein.	0.928
BAN47073.1	BAN47075.1	PCA10_13410	PCA10_13430	enoyl-CoA hydratase/isomerase family protein.	Putative enoyl-CoA hydratase.	0.820
BAN47073.1	BAN47078.1	PCA10_13410	PCA10_13460	enoyl-CoA hydratase/isomerase family protein.	Putative acetyl-CoA acyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	0.789
BAN47073.1	BAN47109.1	PCA10_13410	PCA10_13770	enoyl-CoA hydratase/isomerase family protein.	Putative acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	0.610
BAN47073.1	BAN48000.1	PCA10_13410	PCA10_22680	enoyl-CoA hydratase/isomerase family protein.	enoyl-CoA hydratase/isomerase family protein.	0.472
BAN47073.1	BAN48523.1	PCA10_13410	PCA10_27910	enoyl-CoA hydratase/isomerase family protein.	Putative acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	0.610
BAN47073.1	BAN48551.1	PCA10_13410	PCA10_28190	enoyl-CoA hydratase/isomerase family protein.	Putative enoyl-CoA hydratase.	0.587
BAN47073.1	BAN48563.1	PCA10_13410	PCA10_28310	enoyl-CoA hydratase/isomerase family protein.	Putative enoyl-CoA hydratase.	0.591
BAN47073.1	BAN48585.1	PCA10_13410	PCA10_28530	enoyl-CoA hydratase/isomerase family protein.	Putative acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	0.610
BAN47073.1	BAN48713.1	PCA10_13410	PCA10_29810	enoyl-CoA hydratase/isomerase family protein.	Putative acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	0.610
BAN47073.1	BAN48972.1	PCA10_13410	PCA10_32400	enoyl-CoA hydratase/isomerase family protein.	Putative enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.	0.579
BAN47073.1	BAN48974.1	PCA10_13410	PCA10_32420	enoyl-CoA hydratase/isomerase family protein.	acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	0.610
BAN47073.1	BAN49209.1	PCA10_13410	PCA10_34770	enoyl-CoA hydratase/isomerase family protein.	Putative acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	0.610
BAN47073.1	BAN49399.1	PCA10_13410	PCA10_36670	enoyl-CoA hydratase/isomerase family protein.	Putative enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.	0.584
BAN47073.1	BAN50292.1	PCA10_13410	PCA10_45600	enoyl-CoA hydratase/isomerase family protein.	Putative enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.	0.565
BAN47073.1	BAN50479.1	PCA10_13410	PCA10_47470	enoyl-CoA hydratase/isomerase family protein.	Putative enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.	0.564
BAN47073.1	BAN50521.1	PCA10_13410	PCA10_47890	enoyl-CoA hydratase/isomerase family protein.	acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	0.610