Putative replication protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.

ELONGATION FACTOR P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

Putative replication protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.

Ribosome releasing factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family.

Putative replication protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.

Protein chain elongation factor EF-G, GTP-binding; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase f [...]

Putative replication protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.

GTP-binding elongation factor; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.

Putative replication protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.

Peptide chain release factor RF-1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

Putative replication protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.

50S ribosomal subunit protein L1, regulates synthesis of L1 and L11; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.

Putative replication protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.

50S ribosomal subunit protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.

Putative replication protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.

50S ribosomal subunit protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

Putative replication protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.

50S ribosomal subunit protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.

Putative replication protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.

50S ribosomal protein L9; Binds to the 23S rRNA.

Putative replication protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.

50S ribosomal subunit protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.

Putative replication protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.

50S ribosomal subunit protein L11, N-terminal believed to regulate RelA; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.

Putative replication protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.

50S ribosomal subunit protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family.

Putative replication protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.

50S ribosomal subunit protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family.

Putative replication protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.

50S ribosomal subunit protein L17; Function of strongly homologous gene; structure.

Putative replication protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.

50S ribosomal subunit protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

Putative replication protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.

50S ribosomal subunit protein L20, also posttranslational autoregulator; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

Putative replication protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.

50S ribosomal subunit protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.

Putative replication protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.

50S ribosomal subunit protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family.

Putative replication protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.

50S ribosomal subunit protein L27; Function of homologous gene experimentally demonstrated in an other organism; structure; Belongs to the bacterial ribosomal protein bL27 family.