STRINGSTRING
rsgA rsgA ALO46168.1 ALO46168.1 mltG mltG ALO46173.1 ALO46173.1 folE folE ALO46546.1 ALO46546.1 ALO46904.1 ALO46904.1 coaE coaE pcnB pcnB panB panB panC panC ALO47183.1 ALO47183.1 ALO47221.1 ALO47221.1 ALO47295.1 ALO47295.1 ALO47311.1 ALO47311.1 ALO47373.1 ALO47373.1 ALO47374.1 ALO47374.1 ALO47377.1 ALO47377.1 mutM mutM coaD coaD ALO47603.1 ALO47603.1 ALO45390.1 ALO45390.1 ALO45394.1 ALO45394.1 ALO45395.1 ALO45395.1 ALO45396.1 ALO45396.1 ALO45397.1 ALO45397.1 ALO45398.1 ALO45398.1 ALO45399.1 ALO45399.1 nrdR nrdR ALO45402.1 ALO45402.1 ALO45403.1 ALO45403.1 ribB ribB ribH ribH nusB nusB thiL thiL ribA ribA
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
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rsgAPutative ribosome biogenesis GTPase RsgA; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily. (336 aa)
ALO46168.1Pfam:pfam01063 Aminotransferase class IV. (289 aa)
mltGPutative BCR, YceG family; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family. (343 aa)
ALO46173.1Pfam:pfam04214 Protein of unknown function, DUF. (161 aa)
folEPfam:pfam01227 GTP cyclohydrolase I. (194 aa)
ALO46546.1Pfam:pfam01242 6-pyruvoyl tetrahydropterin synthase. (118 aa)
ALO46904.12-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (324 aa)
coaEDephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (204 aa)
pcnBpoly(A) polymerase; Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control. Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. (511 aa)
panB3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (270 aa)
panCPantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (289 aa)
ALO47183.1Metallophosphatase; Pfam:pfam09423 PhoD-like phosphatase. (351 aa)
ALO47221.1Pfam:pfam00245 Alkaline phosphatase; Belongs to the alkaline phosphatase family. (519 aa)
ALO47295.1Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. (298 aa)
ALO47311.12-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Pfam:pfam01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). (183 aa)
ALO47373.12-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Pfam:pfam01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). (173 aa)
ALO47374.1Dihydroneopterin triphosphate 2'-epimerase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (123 aa)
ALO47377.1Transamidase GatB domain protein; Pfam:pfam09424 Yqey-like protein. (152 aa)
mutM5-hydroxymethyluracil DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. (272 aa)
coaDPhosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (164 aa)
ALO47603.1Phosphopantothenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (411 aa)
ALO45390.1Hypothetical protein; Pfam:pfam05099 Tellurite resistance protein TerB. (147 aa)
ALO45394.1Hypothetical protein. (90 aa)
ALO45395.1Succinylglutamate desuccinylase; Pfam:pfam08856 Protein of unknown function (DUF1826). (199 aa)
ALO45396.1Putative metal chaperone; Pfam:pfam02492 CobW/HypB/UreG, nucleotide-binding domain. (406 aa)
ALO45397.1ABC-type antimicrobial peptide transport system; Pfam:pfam12704 MacB-like periplasmic core domain. (406 aa)
ALO45398.1ABC transporter, ATP-binding protein; Pfam:pfam00005 ABC transporter. (238 aa)
ALO45399.1Pfam:pfam11736 Protein of unknown function (DUF3299). (205 aa)
nrdRNrdR family transcriptional regulator; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. (150 aa)
ALO45402.1Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (371 aa)
ALO45403.1Riboflavin synthase subunit alpha; Pfam:pfam00677 Lumazine binding domain. (218 aa)
ribB3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. (373 aa)
ribH6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family. (158 aa)
nusBN utilization substance protein B; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. (174 aa)
thiLThiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. (344 aa)
ribAGTP cyclohydrolase; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. (196 aa)
Your Current Organism:
Pseudohongiella spirulinae
NCBI taxonomy Id: 1249552
Other names: KCTC 32221, LMG 27470, LMG:27470, Nonhongiella spirulinensis, P. spirulinae, Pseudohongiella spirulinae corrig. Wang et al. 2015, gamma proteobacterium Ma-20, strain Ma-20
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