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hisC | Pfam:pfam00155 Aminotransferase class I and II; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (367 aa) | ||||
ALO45689.1 | Pyruvate carboxylase subunit A; Pfam:pfam02786 Carbamoyl-phosphate synthase L chain, ATP binding domain. (471 aa) | ||||
ALO45794.1 | Hypothetical protein. (318 aa) | ||||
ALO45834.1 | 2-isopropylmalate synthase; Pfam:pfam00682 HMGL-like; Belongs to the alpha-IPM synthase/homocitrate synthase family. (515 aa) | ||||
ALO45837.1 | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. (369 aa) | ||||
leuA | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. (561 aa) | ||||
ALO45907.1 | Pfam:pfam00742 Homoserine dehydrogenase. (447 aa) | ||||
ALO45908.1 | Pfam:pfam14821 Threonine synthase N terminus. (463 aa) | ||||
ALO45913.1 | Aspartokinase; Pfam:pfam00696 Amino acid kinase family; Belongs to the aspartokinase family. (405 aa) | ||||
ALO45938.1 | Phosphopantetheine-binding protein; Pfam:pfam00550 Phosphopantetheine attachment site. (82 aa) | ||||
ALO45980.1 | Short-chain alcohol dehydrogenase; Pfam:pfam00106 short chain dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (254 aa) | ||||
ALO45984.1 | Glutamate synthase; Pfam:pfam01645 Conserved region in glutamate synthase; Belongs to the glutamate synthase family. (540 aa) | ||||
ALO46000.1 | 3-oxoacyl-ACP synthase; Pfam:pfam08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal. (379 aa) | ||||
fabZ | 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (157 aa) | ||||
accA | Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (317 aa) | ||||
kdsA | 2-dehydro-3-deoxyphosphooctonate aldolase; Pfam:pfam00793 DAHP synthetase I family; Belongs to the KdsA family. (286 aa) | ||||
ALO46115.1 | Sulfite reductase; Pfam:pfam01077 Nitrite and sulphite reductase 4Fe-4S domain. (561 aa) | ||||
ALO46118.1 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1232 aa) | ||||
ALO44844.1 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. (181 aa) | ||||
argA | N-acetylglutamate synthase; Pfam:pfam00696 Amino acid kinase family; Belongs to the acetyltransferase family. ArgA subfamily. (440 aa) | ||||
plsX | Phosphate acyltransferase; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. (335 aa) | ||||
ALO46164.1 | Malonyl CoA-acyl carrier protein transacylase; Pfam:pfam00698 Acyl transferase domain. (311 aa) | ||||
ALO46165.1 | 3-ketoacyl-ACP reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (248 aa) | ||||
acpP | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (77 aa) | ||||
ALO44846.1 | Acetylornithine deacetylase; Pfam:pfam01546 Peptidase family M20/M25/M40. (387 aa) | ||||
ALO46167.1 | 3-oxoacyl-ACP synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. (417 aa) | ||||
ALO46168.1 | Pfam:pfam01063 Aminotransferase class IV. (289 aa) | ||||
ALO46196.1 | Pfam:pfam01546 Peptidase family M20/M25/M40. (456 aa) | ||||
serS | Serine--tRNA ligase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (427 aa) | ||||
metXS | Homoserine O-acetyltransferase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine. (399 aa) | ||||
ALO46228.1 | Phosphoserine phosphatase; Pfam:pfam00702 haloacid dehalogenase-like hydrolase. (205 aa) | ||||
proC | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (269 aa) | ||||
dapD | 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase; Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA. (344 aa) | ||||
dapE | Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. (382 aa) | ||||
ALO46245.1 | Cysteine synthase; Pfam:pfam00291 Pyridoxal-phosphate dependent enzyme; Belongs to the cysteine synthase/cystathionine beta- synthase family. (305 aa) | ||||
ALO44857.1 | Glutamate synthase, NADH/NADPH, small subunit; Pfam:pfam14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster. (478 aa) | ||||
ALO44858.1 | Glutamate synthase [NADPH] large chain; Pfam:pfam01645 Conserved region in glutamate synthase. (1524 aa) | ||||
ALO46286.1 | 3-phosphoshikimate 1-carboxyvinyltransferase; Pfam:pfam02153 Prephenate dehydrogenase. (593 aa) | ||||
pheA | Pfam:pfam00800 Prephenate dehydratase. (282 aa) | ||||
argG | Pfam:pfam00764 Arginosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (404 aa) | ||||
ALO46382.1 | Pfam:pfam00202 Aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (451 aa) | ||||
ALO46391.1 | Pfam:pfam03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain. (388 aa) | ||||
argD | Pfam:pfam00202 Aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (394 aa) | ||||
ALO46445.1 | 3-methylcrotonyl-CoA carboxylase beta subunit; Pfam:pfam01039 Carboxyl transferase domain. (533 aa) | ||||
mtnC | Enolase-phosphatase E1; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family. (229 aa) | ||||
aroE | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (280 aa) | ||||
mtnD | Acireductone dioxygenase; Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway. (187 aa) | ||||
ALO46482.1 | Pfam:pfam01063 Aminotransferase class IV. (350 aa) | ||||
ALO46495.1 | Folylpolyglutamate synthase; Pfam:pfam08245 Mur ligase middle domain; Belongs to the folylpolyglutamate synthase family. (456 aa) | ||||
accD | Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (292 aa) | ||||
trpA | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (270 aa) | ||||
trpB | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (414 aa) | ||||
trpF | Pfam:pfam00697 N-(5'phosphoribosyl)anthranilate (PRA) isomerase; Belongs to the TrpF family. (216 aa) | ||||
asd | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (339 aa) | ||||
leuD | 3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (215 aa) | ||||
leuC | 3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (476 aa) | ||||
aroC | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (361 aa) | ||||
dapA | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (291 aa) | ||||
ALO46562.1 | Quinolinate synthetase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (361 aa) | ||||
folD | 5,10-methylene-tetrahydrofolate dehydrogenase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (295 aa) | ||||
ALO46718.1 | Phospho-2-dehydro-3-deoxyheptonate aldolase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). (359 aa) | ||||
proB | Gamma-glutamyl kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (374 aa) | ||||
ALO46755.1 | Pfam:pfam06426 Serine acetyltransferase, N-terminal. (259 aa) | ||||
ilvC | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (489 aa) | ||||
ALO46767.1 | Pfam:pfam10369 Small subunit of acetolactate synthase. (163 aa) | ||||
ALO46768.1 | Thiamine pyrophosphate-requiring protein; Pfam:pfam02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain. (574 aa) | ||||
proA | Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (419 aa) | ||||
ALO46817.1 | Pfam:pfam00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain. (393 aa) | ||||
serC | MFS transporter; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (362 aa) | ||||
ALO46825.1 | Pfam:pfam00109 Beta-ketoacyl synthase, N-terminal domain; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (637 aa) | ||||
ALO46840.1 | Homoserine O-acetyltransferase; Pfam:pfam00561 alpha/beta hydrolase fold; Belongs to the AB hydrolase superfamily. MetX family. (401 aa) | ||||
ALO46847.1 | Hypothetical protein; Pfam:pfam00550 Phosphopantetheine attachment site. (93 aa) | ||||
ALO46904.1 | 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (324 aa) | ||||
argJ | Arginine biosynthesis bifunctional protein ArgJ; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (407 aa) | ||||
hisD | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (444 aa) | ||||
hisG | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily. (218 aa) | ||||
panB | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (270 aa) | ||||
panC | Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (289 aa) | ||||
ALO47115.1 | Pfam:pfam01436 NHL repeat. (366 aa) | ||||
argC | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (355 aa) | ||||
ALO47186.1 | Pfam:pfam01040 UbiA prenyltransferase family; Belongs to the UbiA prenyltransferase family. (475 aa) | ||||
ALO47216.1 | Parallel beta-helix repeat-containing protein; Pfam:pfam13229 Right handed beta helix region. (420 aa) | ||||
hisZ | ATP phosphoribosyltransferase regulatory subunit; Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine. (402 aa) | ||||
carB | Pfam:pfam02786 Carbamoyl-phosphate synthase L chain, ATP binding domain; Belongs to the CarB family. (1075 aa) | ||||
carA | Pfam:pfam00988 Carbamoyl-phosphate synthase small chain, CPSase domain; Belongs to the CarA family. (382 aa) | ||||
dapB | 4-hydroxy-tetrahydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (270 aa) | ||||
bioD | ATP-dependent dethiobiotin synthetase BioD; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. (230 aa) | ||||
bioB | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (332 aa) | ||||
bioA | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily. (435 aa) | ||||
ALO47311.1 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Pfam:pfam01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). (183 aa) | ||||
aroB | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (362 aa) | ||||
aroK | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (188 aa) | ||||
trpC | Pfam:pfam00218 Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. (265 aa) | ||||
trpD | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (342 aa) | ||||
ALO47349.1 | Pfam:pfam04055 Radical SAM superfamily. (320 aa) | ||||
kynU | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. (411 aa) | ||||
lipA | Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (357 aa) | ||||
trpE | Anthranilate/para-aminobenzoate synthases component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorisma [...] (510 aa) | ||||
ALO47373.1 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Pfam:pfam01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). (173 aa) | ||||
ALO47374.1 | Dihydroneopterin triphosphate 2'-epimerase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (123 aa) | ||||
ilvD | Pfam:pfam00920 Dehydratase family; Belongs to the IlvD/Edd family. (558 aa) | ||||
ALO47401.1 | 2-keto-3-deoxy-D-arabino-heptulosonate-7- phosphate synthase II; Pfam:pfam01474 Class-II DAHP synthetase family. (451 aa) | ||||
ALO47430.1 | Pfam:pfam00180 Isocitrate/isopropylmalate dehydrogenase. (489 aa) | ||||
pqqE | Pyrroloquinoline quinone biosynthesis protein PqqE; Catalyzes the cross-linking of a glutamate residue and a tyrosine residue in the PqqA protein as part of the biosynthesis of pyrroloquinoline quinone (PQQ). (381 aa) | ||||
ALO47437.1 | Pfam:pfam05402 Coenzyme PQQ synthesis protein D (PqqD). (90 aa) | ||||
pqqC | Pyrroloquinoline-quinone synthase; Ring cyclization and eight-electron oxidation of 3a-(2-amino- 2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9- dicarboxylic-acid to PQQ. (246 aa) | ||||
pqqB | Coenzyme PQQ synthesis protein B; May be involved in the transport of PQQ or its precursor to the periplasm; Belongs to the PqqB family. (305 aa) | ||||
ilvD-2 | Pfam:pfam00920 Dehydratase family; Belongs to the IlvD/Edd family. (616 aa) | ||||
ALO44980.1 | Pfam:pfam01546 Peptidase family M20/M25/M40. (471 aa) | ||||
fabV | trans-2-enoyl-CoA reductase; Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon- carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP); Belongs to the TER reductase family. (398 aa) | ||||
ALO47517.1 | Glutamate carboxypeptidase; Pfam:pfam01546 Peptidase family M20/M25/M40. (427 aa) | ||||
ALO47546.1 | Pfam:pfam00583 Acetyltransferase (GNAT) family. (153 aa) | ||||
thrB | Homoserine kinase; Pfam:pfam01636 Phosphotransferase enzyme family; Belongs to the pseudomonas-type ThrB family. (327 aa) | ||||
ALO47582.1 | Pfam:pfam00561 alpha/beta hydrolase fold. (344 aa) | ||||
argB | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (305 aa) | ||||
ALO47629.1 | Carboxylate--amine ligase; Pfam:pfam13535 ATP-grasp domain. (408 aa) | ||||
ALO47644.1 | Periplasmic ATP/GTP-binding protein; Pfam:pfam08450 SMP-30/Gluconolaconase/LRE-like region. (307 aa) | ||||
selD | Selenide, water dikinase; Synthesizes selenophosphate from selenide and ATP. (350 aa) | ||||
ALO45047.1 | Phospho-2-dehydro-3-deoxyheptonate aldolase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). (358 aa) | ||||
dapF | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (319 aa) | ||||
lysA | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (418 aa) | ||||
argH | Pfam:pfam00206 Lyase. (490 aa) | ||||
ALO45115.1 | Hypothetical protein; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. (262 aa) | ||||
hisB | Pfam:pfam00475 Imidazoleglycerol-phosphate dehydratase. (246 aa) | ||||
hisH | Imidazole glycerol phosphate synthase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (217 aa) | ||||
hisA | 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; Pfam:pfam00977 Histidine biosynthesis protein. (247 aa) | ||||
hisF | Imidazole glycerol phosphate synthase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (257 aa) | ||||
ALO45180.1 | Pfam:pfam00120 Glutamine synthetase, catalytic domain. (469 aa) | ||||
hisE | Pfam:pfam01503 Phosphoribosyl-ATP pyrophosphohydrolase. (110 aa) | ||||
hisI | phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. (144 aa) | ||||
ALO45197.1 | acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (449 aa) | ||||
ALO45198.1 | acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (155 aa) | ||||
aroQ | 3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (148 aa) | ||||
ALO45201.1 | Pfam:pfam00109 Beta-ketoacyl synthase, N-terminal domain; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (405 aa) | ||||
fabA | 3-hydroxydecanoyl-ACP dehydratase; Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E- (2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length. (175 aa) | ||||
ALO45305.1 | Serum paraoxonase/arylesterase; Pfam:pfam01731 Arylesterase. (361 aa) | ||||
ALO45333.1 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. (393 aa) | ||||
aroA | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (426 aa) | ||||
ALO45384.1 | Hypothetical protein; Pfam:pfam08282 haloacid dehalogenase-like hydrolase. (286 aa) | ||||
glyA | Serine hydroxymethyltransferase 2; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (419 aa) | ||||
mtnA | Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). (371 aa) | ||||
ALO45506.1 | Hypothetical protein; Pfam:pfam00155 Aminotransferase class I and II. (372 aa) | ||||
PS2015_86 | Pfam:pfam02219 Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (281 aa) | ||||
ALO45538.1 | Di-and tripeptidase; Pfam:pfam01546 Peptidase family M20/M25/M40. (413 aa) | ||||
ALO45547.1 | Integrase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. (1013 aa) | ||||
ectC | Ectoine synthase; Catalyzes the circularization of gamma-N-acetyl-alpha,gamma- diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4- pyrimidine carboxylic acid), which is an excellent osmoprotectant. (128 aa) | ||||
ectA | L-2,4-diaminobutyric acid acetyltransferase; Catalyzes the acetylation of L-2,4-diaminobutyrate (DABA) to gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) with acetyl coenzyme A. (180 aa) | ||||
PS2015_95 | Pfam:pfam00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain. (409 aa) | ||||
ALO45634.1 | Phosphoserine phosphatase; Pfam:pfam13740 ACT domain. (403 aa) | ||||
ilvA | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (523 aa) |