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| | ALO45603.1 | Cys-tRNA(Pro)/Cys-tRNA(Cys) deacylase; Pfam:pfam04073 Aminoacyl-tRNA editing domain; Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily. (159 aa) |
| | prfC | Peptide chain release factor 3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily. (528 aa) |
| | ALO45689.1 | Pyruvate carboxylase subunit A; Pfam:pfam02786 Carbamoyl-phosphate synthase L chain, ATP binding domain. (471 aa) |
| | ileS | Isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. (944 aa) |
| | ALO45732.1 | Amidase; Pfam:pfam01425 Amidase. (520 aa) |
| | ALO45770.1 | Pfam:pfam13417 Glutathione S-transferase, N-terminal domain. (225 aa) |
| | ALO45779.1 | Pfam:pfam13409 Glutathione S-transferase, N-terminal domain; Belongs to the GST superfamily. (199 aa) |
| | valS | Valine--tRNA ligase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. (936 aa) |
| | ALO45853.1 | Amidohydrolase; Pfam:pfam01979 Amidohydrolase family. (966 aa) |
| | ALO45854.1 | Amidohydrolase; Pfam:pfam13147 Amidohydrolase. (439 aa) |
| | hisS | Histidine--tRNA ligase; Pfam:pfam13393 Histidyl-tRNA synthetase. (430 aa) |
| | rpsP | Pfam:pfam00886 Ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family. (86 aa) |
| | rplS | 50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. (121 aa) |
| | alaS | Alanine--tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (884 aa) |
| | ALO45935.1 | Acetyl-coenzyme A synthetase; Pfam:pfam00501 AMP-binding enzyme. (574 aa) |
| | pdhA | Dehydrogenase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (667 aa) |
| | ALO45944.1 | Hypothetical protein; Pfam:pfam00009 Elongation factor Tu GTP binding domain. (631 aa) |
| | selA | Selenocysteine synthase; Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis. (467 aa) |
| | fmt | Methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. (329 aa) |
| | ALO45963.1 | Pfam:pfam01019 Gamma-glutamyltranspeptidase. (585 aa) |
| | ALO46033.1 | GTPase; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily. (304 aa) |
| | rpsB | Pfam:pfam00318 Ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family. (259 aa) |
| | tsf | Elongation factor Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family. (292 aa) |
| | frr | Ribosome-recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. (185 aa) |
| | accA | Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (317 aa) |
| | def | Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. (170 aa) |
| | gltX | Glutamate--tRNA ligase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). (509 aa) |
| | argS | Arginine--tRNA ligase; Pfam:pfam00750 tRNA synthetases class I (R). (578 aa) |
| | rpmF | Pfam:pfam01783 Ribosomal L32p protein family; Belongs to the bacterial ribosomal protein bL32 family. (59 aa) |
| | ALO46168.1 | Pfam:pfam01063 Aminotransferase class IV. (289 aa) |
| | ALO46175.1 | Glutathione reductase; Pfam:pfam07992 Pyridine nucleotide-disulphide oxidoreductase. (455 aa) |
| | ALO46185.1 | Beta-lactamase hydrolase-family protein; Pfam:pfam04273 Putative phosphatase (DUF442). (195 aa) |
| | serS | Serine--tRNA ligase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (427 aa) |
| | infA | Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. (72 aa) |
| | ALO46249.1 | Pfam:pfam10502 Signal peptidase, peptidase S26; Belongs to the peptidase S26 family. (257 aa) |
| | lepA | Elongation factor 4; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. (599 aa) |
| | pheT | Phenylalanyl-tRNA synthetase; Pfam:pfam03483 B3/4 domain; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. (794 aa) |
| | pheS | Pfam:pfam01409 tRNA synthetases class II core domain (F); Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. (346 aa) |
| | rplT | 50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. (118 aa) |
| | rpmI | Pfam:pfam01632 Ribosomal protein L35; Belongs to the bacterial ribosomal protein bL35 family. (64 aa) |
| | infC | Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins. (176 aa) |
| | ALO46284.1 | 30S ribosomal protein S1; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence. (558 aa) |
| | trpS | tryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family. (404 aa) |
| | metG | Methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (697 aa) |
| | ALO46379.1 | Gamma-glutamyltransferase; Pfam:pfam01019 Gamma-glutamyltranspeptidase. (545 aa) |
| | ALO46382.1 | Pfam:pfam00202 Aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (451 aa) |
| | ALO46384.1 | Acetoacetyl-CoA synthetase; Pfam:pfam00501 AMP-binding enzyme. (649 aa) |
| | ALO46448.1 | Acetoacetyl-CoA synthetase; Pfam:pfam00682 HMGL-like. (952 aa) |
| | ALO46491.1 | Pfam:pfam01253 Translation initiation factor SUI1. (121 aa) |
| | ALO46495.1 | Folylpolyglutamate synthase; Pfam:pfam08245 Mur ligase middle domain; Belongs to the folylpolyglutamate synthase family. (456 aa) |
| | accD | Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (292 aa) |
| | efp | Elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. (188 aa) |
| | cysS | Pfam:pfam01406 tRNA synthetases class I (C) catalytic domain; Belongs to the class-I aminoacyl-tRNA synthetase family. (466 aa) |
| | glnS | Glutamine--tRNA ligase; Pfam:pfam00749 tRNA synthetases class I (E and Q), catalytic domain. (579 aa) |
| | lysS | Pfam:pfam00152 tRNA synthetases class II (D, K and N); Belongs to the class-II aminoacyl-tRNA synthetase family. (508 aa) |
| | prfB | Peptide chain release factor 2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. (299 aa) |
| | aspS | aspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. (593 aa) |
| | proS | Proline--tRNA ligase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacy [...] (579 aa) |
| | ALO46670.1 | Pfam:pfam13275 S4 domain. (71 aa) |
| | rpsT | 30S ribosomal protein S20; Binds directly to 16S ribosomal RNA. (88 aa) |
| | rpmA | Pfam:pfam01016 Ribosomal L27 protein; Belongs to the bacterial ribosomal protein bL27 family. (85 aa) |
| | rplU | 50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. (103 aa) |
| | leuS | Leucine--tRNA ligase; Pfam:pfam13603 Leucyl-tRNA synthetase, Domain 2; Belongs to the class-I aminoacyl-tRNA synthetase family. (826 aa) |
| | ALO46904.1 | 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (324 aa) |
| | ALO46949.1 | Stringent starvation protein A; Pfam:pfam13417 Glutathione S-transferase, N-terminal domain. (210 aa) |
| | rpsI | Pfam:pfam00380 Ribosomal protein S9/S16; Belongs to the universal ribosomal protein uS9 family. (130 aa) |
| | rplM | 50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. (142 aa) |
| | gluQ | Glutamyl-Q tRNA(Asp) synthetase; Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2- cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon; Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily. (301 aa) |
| | panB | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (270 aa) |
| | panC | Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (289 aa) |
| | acsA | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (645 aa) |
| | ALO46999.1 | Sulfide:quinone oxidoreductase; Pfam:pfam04273 Putative phosphatase (DUF442). (142 aa) |
| | ALO44932.1 | Addiction module toxin. (92 aa) |
| | ALO47036.1 | Beta-lactamase; Pfam:pfam00753 Metallo-beta-lactamase superfamily. (346 aa) |
| | rplQ | Pfam:pfam01196 Ribosomal protein L17. (130 aa) |
| | rpsD | 30S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. (206 aa) |
| | rpsK | 30S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family. (132 aa) |
| | rpsM | 30S ribosomal protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites. Belongs to the universal ribosomal protein uS13 family. (118 aa) |
| | rplO | 50S ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. (161 aa) |
| | rpmD | Pfam:pfam00327 Ribosomal protein L30p/L7e. (60 aa) |
| | rpsE | 30S ribosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family. (169 aa) |
| | rplR | 50S ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. (116 aa) |
| | rplF | 50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. (177 aa) |
| | rpsH | 30S ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. (131 aa) |
| | rpsN | 30S ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family. (101 aa) |
| | rplE | 50S ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. (189 aa) |
| | rplX | 50S ribosomal protein L24; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit. (103 aa) |
| | rplN | 50S ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. (122 aa) |
| | rpsQ | 30S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (92 aa) |
| | rpmC | Pfam:pfam00831 Ribosomal L29 protein; Belongs to the universal ribosomal protein uL29 family. (65 aa) |
| | rplP | 50S ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family. (137 aa) |
| | rpsC | 30S ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family. (222 aa) |
| | rplV | 50S ribosomal protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome. (110 aa) |
| | rpsS | 30S ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. (91 aa) |
| | rplB | 50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. (276 aa) |
| | rplW | 50S ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family. (99 aa) |
| | rplD | 50S ribosomal protein L4; Forms part of the polypeptide exit tunnel. (207 aa) |
| | rplC | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. (217 aa) |
| | rpsJ | 30S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. (103 aa) |
| | tuf | Elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (398 aa) |
| | fusA | Elongation factor G 1; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. (698 aa) |
| | rpsG | 30S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family. (156 aa) |
| | rpsL | 30S ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit. (124 aa) |
| | rplL | 50S ribosomal protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family. (126 aa) |
| | rplJ | 50S ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. (175 aa) |
| | rplA | 50S ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. (231 aa) |
| | rplK | 50S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. (144 aa) |
| | ALO47103.1 | Pfam:pfam00009 Elongation factor Tu GTP binding domain. (398 aa) |
| | tyrS | tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily. (429 aa) |
| | smpB | SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...] (160 aa) |
| | ALO47167.1 | Pfam:pfam00043 Glutathione S-transferase, C-terminal domain; Belongs to the GST superfamily. (284 aa) |
| | ALO47178.1 | Pfam:pfam13622 Thioesterase-like superfamily. (268 aa) |
| | ALO47209.1 | Pfam:pfam13409 Glutathione S-transferase, N-terminal domain. (206 aa) |
| | ALO47224.1 | Amidase; Pfam:pfam01425 Amidase. (515 aa) |
| | ALO47274.1 | Hypothetical protein; Pfam:pfam13147 Amidohydrolase. (449 aa) |
| | ALO44957.1 | Hydroxylase; Pfam:pfam12681 Glyoxalase-like domain. (114 aa) |
| | rpsO | 30S ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome. (89 aa) |
| | infB | Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. (860 aa) |
| | bioD | ATP-dependent dethiobiotin synthetase BioD; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. (230 aa) |
| | bioB | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (332 aa) |
| | bioA | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily. (435 aa) |
| | ALO47311.1 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Pfam:pfam01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). (183 aa) |
| | rpmE | 50S ribosomal protein L31; Binds the 23S rRNA. (69 aa) |
| | ALO47373.1 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Pfam:pfam01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). (173 aa) |
| | ALO47374.1 | Dihydroneopterin triphosphate 2'-epimerase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (123 aa) |
| | rpsU | Pfam:pfam01165 Ribosomal protein S21; Belongs to the bacterial ribosomal protein bS21 family. (71 aa) |
| | ALO47396.1 | Maleylacetoacetate isomerase; Pfam:pfam13409 Glutathione S-transferase, N-terminal domain. (211 aa) |
| | ALO47420.1 | 2-oxoisovalerate dehydrogenase subunit beta; Pfam:pfam02780 Transketolase, C-terminal domain. (715 aa) |
| | ALO47457.1 | Gamma-glutamyltransferase; Pfam:pfam01019 Gamma-glutamyltranspeptidase. (601 aa) |
| | ALO47468.1 | Hypothetical protein; Pfam:pfam13354 Beta-lactamase enzyme family. (293 aa) |
| | ALO47499.1 | Pfam:pfam01019 Gamma-glutamyltranspeptidase. (567 aa) |
| | ALO47538.1 | Pfam:pfam08443 RimK-like ATP-grasp domain. (300 aa) |
| | ALO47553.1 | Hypothetical protein; Pfam:pfam03781 Sulfatase-modifying factor enzyme 1. (274 aa) |
| | ALO47561.1 | Beta-lactamase; Pfam:pfam00753 Metallo-beta-lactamase superfamily. (290 aa) |
| | ALO47562.1 | NAD(FAD)-dependent dehydrogenase; Pfam:pfam04273 Putative phosphatase (DUF442). (574 aa) |
| | ALO47572.1 | PEGA domain family protein; Pfam:pfam03781 Sulfatase-modifying factor enzyme 1. (697 aa) |
| | rpmG | Pfam:pfam00471 Ribosomal protein L33; Belongs to the bacterial ribosomal protein bL33 family. (51 aa) |
| | rpmB | Pfam:pfam00830 Ribosomal L28 family; Belongs to the bacterial ribosomal protein bL28 family. (78 aa) |
| | ALO47603.1 | Phosphopantothenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (411 aa) |
| | ALO47629.1 | Carboxylate--amine ligase; Pfam:pfam13535 ATP-grasp domain. (408 aa) |
| | ALO47636.1 | Acetoacetyl-CoA synthase; Pfam:pfam00501 AMP-binding enzyme. (702 aa) |
| | ALO47660.1 | Acyl-CoA thioester hydrolase YciA; Pfam:pfam03061 Thioesterase superfamily. (139 aa) |
| | rpmH | Pfam:pfam00468 Ribosomal protein L34; Belongs to the bacterial ribosomal protein bL34 family. (44 aa) |
| | ALO45023.1 | Pfam:pfam02551 Acyl-CoA thioesterase. (290 aa) |
| | ALO45049.1 | Pfam:pfam13409 Glutathione S-transferase, N-terminal domain. (220 aa) |
| | efp-2 | Elongation factor P; Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation; Belongs to the elongation factor P family. (189 aa) |
| | ALO45080.1 | poxB regulator PoxA; Pfam:pfam00152 tRNA synthetases class II (D, K and N). (321 aa) |
| | ALO45089.1 | Pfam:pfam00717 Peptidase S24-like; Belongs to the peptidase S26 family. (235 aa) |
| | gshB | Pfam:pfam02955 Prokaryotic glutathione synthetase, ATP-grasp domain; Belongs to the prokaryotic GSH synthase family. (317 aa) |
| | gshA | Pfam:pfam04262 Glutamate-cysteine ligase; Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily. (520 aa) |
| | ALO45197.1 | acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (449 aa) |
| | ALO45207.1 | Putative alpha-L-glutamate ligase; Pfam:pfam08443 RimK-like ATP-grasp domain. (469 aa) |
| | rimK | Putative alpha-L-glutamate ligase 2; Pfam:pfam08443 RimK-like ATP-grasp domain; Belongs to the RimK family. (304 aa) |
| | ALO45265.1 | Glutathione synthase; Pfam:pfam14401 RimK-like ATPgrasp N-terminal domain. (488 aa) |
| | ALO45310.1 | Hypothetical protein. (494 aa) |
| | rpsF | 30S ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA. (158 aa) |
| | rpsR | 30S ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family. (76 aa) |
| | rplI | 50S ribosomal protein L9; Binds to the 23S rRNA. (148 aa) |
| | glyS | Pfam:pfam02092 Glycyl-tRNA synthetase beta subunit. (693 aa) |
| | pth | peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. (201 aa) |
| | rplY | 50S ribosomal protein L25; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily. (211 aa) |
| | prfA | Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. (360 aa) |
| | gatB | Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily. (477 aa) |
| | ALO45612.1 | Pfam:pfam03486 HI0933-like protein. (424 aa) |
| | gatA | glutamyl-tRNA amidotransferase; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). (482 aa) |
| | gatC | Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family. (95 aa) |
| | glyQ | Pfam:pfam02091 Glycyl-tRNA synthetase alpha subunit. (305 aa) |
| | ALO45481.1 | Beta-lactamase; Pfam:pfam00753 Metallo-beta-lactamase superfamily. (293 aa) |
| | ALO45518.1 | Class I peptide chain release factor; Pfam:pfam00472 RF-1 domain. (133 aa) |
