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purD purD purH purH pyrC pyrC pyrB pyrB pyrR pyrR purC purC purE purE purK purK pyrC-2 pyrC-2 cvpA cvpA purF purF pyrD pyrD pyrF pyrF purL purL glyA glyA carB carB carA carA folD folD purM purM purN purN AGA35379.1 AGA35379.1 pyrE pyrE
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
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gene fusions
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purDPhosphoribosylamine--glycine ligase; Belongs to the GARS family. (428 aa)
purHIMP cyclohydrolase / Phosphoribosylaminoimidazolecarboxamide formyltransferase. (521 aa)
pyrCDihydroorotase. (430 aa)
pyrBAspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (335 aa)
pyrRUracil phosphoribosyltransferase / Pyrimidine operon regulatory protein PyrR. (168 aa)
purCPhosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. (295 aa)
purEPhosphoribosylaminoimidazole carboxylase catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (156 aa)
purKPhosphoribosylaminoimidazole carboxylase ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (388 aa)
pyrC-2Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate. (345 aa)
cvpAColicin V production protein. (169 aa)
purFAmidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (501 aa)
pyrDDihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (340 aa)
pyrFOrotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. (246 aa)
purLPhosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. (1295 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (419 aa)
carBCarbamoyl-phosphate synthase large chain; Belongs to the CarB family. (1079 aa)
carACarbamoyl-phosphate synthase small chain; Belongs to the CarA family. (377 aa)
folDMethylenetetrahydrofolate dehydrogenase (NADP+)/Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (289 aa)
purMPhosphoribosylformylglycinamidine cyclo-ligase. (353 aa)
purNPhosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (244 aa)
AGA35379.1Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. (358 aa)
pyrEOrotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (214 aa)
Your Current Organism:
Thioalkalivibrio nitratireducens
NCBI taxonomy Id: 1255043
Other names: T. nitratireducens DSM 14787, Thioalkalivibrio nitratireducens ALEN 2, Thioalkalivibrio nitratireducens DSM 14787, Thioalkalivibrio nitratireducens str. DSM 14787, Thioalkalivibrio nitratireducens strain DSM 14787
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