STRINGSTRING
AHM58434.1 AHM58434.1 AHM58934.1 AHM58934.1 AHM58938.1 AHM58938.1 AHM58959.1 AHM58959.1 AHM59395.1 AHM59395.1 AHM59413.1 AHM59413.1 hisB hisB hisC hisC hisD hisD hisG hisG AHM59756.1 AHM59756.1 trpA trpA trpB trpB trpF trpF AHM59760.1 AHM59760.1 trpD trpD AHM59762.1 AHM59762.1 AHM59763.1 AHM59763.1 aroQ aroQ AHM59826.1 AHM59826.1 AHM59854.1 AHM59854.1 AHM60401.1 AHM60401.1 hisA hisA aroE aroE AHM60970.1 AHM60970.1 AHM60990.1 AHM60990.1 aroC aroC AHM61364.1 AHM61364.1 asd asd AHM61522.1 AHM61522.1 AHM61737.1 AHM61737.1 AHM61786.1 AHM61786.1 AHM61793.1 AHM61793.1 AHM61874.1 AHM61874.1 AHM61876.1 AHM61876.1 AHM61877.1 AHM61877.1 AHM62112.1 AHM62112.1 AHM62404.1 AHM62404.1 AHM62405.1 AHM62405.1 argC argC AHM62408.1 AHM62408.1 AHM62409.1 AHM62409.1 AHM62410.1 AHM62410.1 argB argB AHM62412.1 AHM62412.1 argH argH asnA asnA hisH hisH hisA-2 hisA-2 hisF hisF hisI hisI aroK aroK asnB asnB AHM63364.1 AHM63364.1 AHM63499.1 AHM63499.1 AHM63522.1 AHM63522.1 thrB thrB thrA thrA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AHM58434.1COG0367 Asparagine synthase (glutamine-hydrolyzing). (614 aa)
AHM58934.1D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (630 aa)
AHM58938.1Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. (366 aa)
AHM58959.1COG0147 Anthranilate/para-aminobenzoate synthases component I. (432 aa)
AHM59395.1L-asparaginase type I family protein; COG0252 L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D. (358 aa)
AHM59413.1D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein; COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (317 aa)
hisBImidazole glycerol-phosphate dehydratase/histidinol phosphatase; COG0241 Histidinol phosphatase and related phosphatases; In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family. (366 aa)
hisCCOG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (355 aa)
hisDHistidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (430 aa)
hisGATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily. (285 aa)
AHM59756.1COG2876 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase. (337 aa)
trpATryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (265 aa)
trpBTryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (400 aa)
trpFCOG0135 Phosphoribosylanthranilate isomerase; Belongs to the TrpF family. (219 aa)
AHM59760.1COG0134 Indole-3-glycerol phosphate synthase. (281 aa)
trpDAnthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (337 aa)
AHM59762.1COG0512 Anthranilate/para-aminobenzoate synthases component II. (191 aa)
AHM59763.1COG0147 Anthranilate/para-aminobenzoate synthases component I. (477 aa)
aroQ3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (142 aa)
AHM59826.1COG0075 Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase. (355 aa)
AHM59854.1COG0527 Aspartokinases; Belongs to the aspartokinase family. (417 aa)
AHM60401.1COG0436 Aspartate/tyrosine/aromatic aminotransferase. (398 aa)
hisAHistidine biosynthesis protein; COG0106 Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase. (244 aa)
aroECOG0169 Shikimate 5-dehydrogenase. (249 aa)
AHM60970.1COG0367 Asparagine synthase (glutamine-hydrolyzing). (640 aa)
AHM60990.1HAD family hydrolase; COG0560 Phosphoserine phosphatase. (205 aa)
aroCChorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (359 aa)
AHM61364.1Beta-aspartyl-peptidase; COG1446 Asparaginase. (337 aa)
asdAspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (331 aa)
AHM61522.1Asparagine synthetase B; COG0367 Asparagine synthase (glutamine-hydrolyzing). (626 aa)
AHM61737.1Glutamine amidotransferase of anthranilate synthase; COG0512 Anthranilate/para-aminobenzoate synthases component II. (191 aa)
AHM61786.1COG0367 Asparagine synthase (glutamine-hydrolyzing). (634 aa)
AHM61793.1COG0527 Aspartokinases; Belongs to the aspartokinase family. (439 aa)
AHM61874.13-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (409 aa)
AHM61876.13-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (352 aa)
AHM61877.1COG2876 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase. (350 aa)
AHM62112.1COG1605 Chorismate mutase. (358 aa)
AHM62404.1GCN5-related N-acetyltransferase; COG0454 Histone acetyltransferase HPA2 and related acetyltransferases. (243 aa)
AHM62405.1COG0137 Argininosuccinate synthase. (399 aa)
argCN-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (322 aa)
AHM62408.1COG4992 Ornithine/acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (382 aa)
AHM62409.1COG0078 Ornithine carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. (313 aa)
AHM62410.1Hypothetical protein; COG0055 F0F1-type ATP synthase, beta subunit. (189 aa)
argBN-acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (259 aa)
AHM62412.1Peptidase M20; COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases. (357 aa)
argHCOG0165 Argininosuccinate lyase. (447 aa)
asnACOG2502 Asparagine synthetase A. (347 aa)
hisHImidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (193 aa)
hisA-2COG0106 Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase. (243 aa)
hisFImidazole glycerol phosphate synthase cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (251 aa)
hisIphosphoribosyl-ATP pyrophosphohydrolase; COG0139 Phosphoribosyl-AMP cyclohydrolase; In the N-terminal section; belongs to the PRA-CH family. (203 aa)
aroKShikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (176 aa)
asnBAsparagine synthetase B; COG0367 Asparagine synthase (glutamine-hydrolyzing). (555 aa)
AHM63364.1COG0287 Prephenate dehydrogenase. (290 aa)
AHM63499.1Aminotransferase; COG0436 Aspartate/tyrosine/aromatic aminotransferase. (440 aa)
AHM63522.1COG0498 Threonine synthase. (431 aa)
thrBHomoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (315 aa)
thrABifunctional aspartokinase I/homoserine dehydrogenase I; COG0527 Aspartokinases. (816 aa)
Your Current Organism:
Flammeovirgaceae bacterium 311
NCBI taxonomy Id: 1257021
Other names: F. bacterium 311
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