STRINGSTRING
AHM63511.1 AHM63511.1 AHM58288.1 AHM58288.1 AHM58291.1 AHM58291.1 AHM58294.1 AHM58294.1 AHM58314.1 AHM58314.1 dinB dinB AHM58331.1 AHM58331.1 AHM58335.1 AHM58335.1 AHM58336.1 AHM58336.1 AHM58378.1 AHM58378.1 AHM58383.1 AHM58383.1 AHM58439.1 AHM58439.1 AHM58462.1 AHM58462.1 AHM58477.1 AHM58477.1 AHM58529.1 AHM58529.1 AHM58566.1 AHM58566.1 pdxH pdxH accA accA queA-2 queA-2 AHM58667.1 AHM58667.1 purU purU purL purL AHM58777.1 AHM58777.1 AHM58826.1 AHM58826.1 AHM58835.1 AHM58835.1 AHM58837.1 AHM58837.1 AHM58893.1 AHM58893.1 AHM58910.1 AHM58910.1 AHM58938.1 AHM58938.1 AHM58941.1 AHM58941.1 AHM58974.1 AHM58974.1 mobA mobA AHM58987.1 AHM58987.1 AHM58988.1 AHM58988.1 AHM58989.1 AHM58989.1 AHM58998.1 AHM58998.1 AHM59013.1 AHM59013.1 AHM59025.1 AHM59025.1 nadE nadE AHM59057.1 AHM59057.1 AHM59142.1 AHM59142.1 AHM59158.1 AHM59158.1 folE folE AHM59168.1 AHM59168.1 AHM59173.1 AHM59173.1 AHM59276.1 AHM59276.1 AHM59277.1 AHM59277.1 AHM59348.1 AHM59348.1 AHM59364.1 AHM59364.1 AHM59413.1 AHM59413.1 AHM59417.1 AHM59417.1 murA murA AHM59481.1 AHM59481.1 AHM59531.1 AHM59531.1 coaD coaD pyrE pyrE kdsB kdsB hemL hemL guaA guaA AHM59578.1 AHM59578.1 AHM59582.1 AHM59582.1 AHM59585.1 AHM59585.1 bioD bioD bioB bioB AHM59591.1 AHM59591.1 thyA thyA AHM59612.1 AHM59612.1 AHM59652.1 AHM59652.1 AHM59653.1 AHM59653.1 AHM59714.1 AHM59714.1 trpA trpA trpB trpB trpF trpF AHM59760.1 AHM59760.1 trpD trpD pyrG pyrG cmk cmk AHM59819.1 AHM59819.1 pyrD pyrD AHM59865.1 AHM59865.1 purD purD hemA hemA purC purC AHM59948.1 AHM59948.1 AHM59970.1 AHM59970.1 AHM59973.1 AHM59973.1 AHM60024.1 AHM60024.1 AHM60106.1 AHM60106.1 AHM60112.1 AHM60112.1 AHM60163.1 AHM60163.1 carA carA rpoA rpoA rpoC rpoC rpoB rpoB nusG nusG pyrH pyrH nadD nadD AHM60217.1 AHM60217.1 AHM60219.1 AHM60219.1 AHM60235.1 AHM60235.1 AHM60267.1 AHM60267.1 AHM60269.1 AHM60269.1 AHM60270.1 AHM60270.1 AHM60290.1 AHM60290.1 AHM60378.1 AHM60378.1 AHM60402.1 AHM60402.1 hemE hemE upp upp AHM60419.1 AHM60419.1 adk adk AHM60454.1 AHM60454.1 atpD atpD AHM60458.1 AHM60458.1 AHM60465.1 AHM60465.1 AHM60489.1 AHM60489.1 AHM60503.1 AHM60503.1 AHM60516.1 AHM60516.1 AHM60537.1 AHM60537.1 AHM60611.1 AHM60611.1 accD accD AHM60642.1 AHM60642.1 rho rho AHM60651.1 AHM60651.1 AHM60721.1 AHM60721.1 coaE coaE AHM60734.1 AHM60734.1 AHM60772.1 AHM60772.1 AHM60805.1 AHM60805.1 kynU kynU kmo kmo AHM60934.1 AHM60934.1 AHM60995.1 AHM60995.1 AHM61004.1 AHM61004.1 AHM61008.1 AHM61008.1 coaX coaX purK purK purE purE atpG atpG atpA atpA atpH atpH atpF atpF atpE atpE atpB atpB AHM61048.1 AHM61048.1 guaB guaB AHM61072.1 AHM61072.1 AHM61075.1 AHM61075.1 AHM61082.1 AHM61082.1 polA polA AHM61286.1 AHM61286.1 nusA nusA AHM61329.1 AHM61329.1 AHM63638.1 AHM63638.1 thiC thiC AHM61331.1 AHM61331.1 AHM61332.1 AHM61332.1 thiE thiE thiG thiG AHM61335.1 AHM61335.1 AHM61336.1 AHM61336.1 AHM61375.1 AHM61375.1 AHM61376.1 AHM61376.1 AHM61389.1 AHM61389.1 AHM61421.1 AHM61421.1 AHM61454.1 AHM61454.1 AHM61518.1 AHM61518.1 AHM61585.1 AHM61585.1 AHM63549.1 AHM63549.1 fcl fcl tdk tdk AHM61642.1 AHM61642.1 AHM61657.1 AHM61657.1 AHM61666.1 AHM61666.1 AHM61667.1 AHM61667.1 AHM61675.1 AHM61675.1 AHM61682.1 AHM61682.1 AHM61719.1 AHM61719.1 AHM61724.1 AHM61724.1 AHM61732.1 AHM61732.1 pdxJ pdxJ ppnK ppnK purH purH purN purN AHM61769.1 AHM61769.1 ribH ribH pdhA pdhA hemH hemH AHM61821.1 AHM61821.1 AHM61830.1 AHM61830.1 hemC hemC AHM61836.1 AHM61836.1 AHM61837.1 AHM61837.1 comB comB AHM61889.1 AHM61889.1 dxs dxs ndk ndk AHM61927.1 AHM61927.1 AHM61947.1 AHM61947.1 AHM61957.1 AHM61957.1 lipA lipA AHM61994.1 AHM61994.1 queA queA AHM62043.1 AHM62043.1 dnaX dnaX AHM62055.1 AHM62055.1 AHM62058.1 AHM62058.1 AHM62064.1 AHM62064.1 AHM62065.1 AHM62065.1 AHM62066.1 AHM62066.1 AHM62068.1 AHM62068.1 AHM62090.1 AHM62090.1 AHM62097.1 AHM62097.1 AHM62104.1 AHM62104.1 AHM62139.1 AHM62139.1 AHM62155.1 AHM62155.1 pyrB pyrB AHM62175.1 AHM62175.1 AHM62190.1 AHM62190.1 thiL thiL fcl-2 fcl-2 AHM62209.1 AHM62209.1 AHM62353.1 AHM62353.1 AHM62389.1 AHM62389.1 proC proC AHM62425.1 AHM62425.1 folD folD queE queE AHM62450.1 AHM62450.1 purA purA AHM62492.1 AHM62492.1 AHM62494.1 AHM62494.1 AHM62498.1 AHM62498.1 AHM62499.1 AHM62499.1 ctaB ctaB AHM62510.1 AHM62510.1 AHM62542.1 AHM62542.1 AHM62543.1 AHM62543.1 AHM62551.1 AHM62551.1 AHM62572.1 AHM62572.1 dut dut dacA dacA AHM62595.1 AHM62595.1 AHM62608.1 AHM62608.1 AHM62685.1 AHM62685.1 AHM62696.1 AHM62696.1 AHM62763.1 AHM62763.1 AHM62767.1 AHM62767.1 AHM62805.1 AHM62805.1 AHM62894.1 AHM62894.1 AHM62900.1 AHM62900.1 AHM62962.1 AHM62962.1 ackA ackA AHM62975.1 AHM62975.1 AHM62984.1 AHM62984.1 AHM63009.1 AHM63009.1 AHM63012.1 AHM63012.1 AHM63090.1 AHM63090.1 AHM63234.1 AHM63234.1 priA priA ribBA ribBA dnaG dnaG apaG apaG AHM63333.1 AHM63333.1 AHM63334.1 AHM63334.1 pncB pncB tgt tgt AHM63372.1 AHM63372.1 AHM63410.1 AHM63410.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AHM63511.1Bifunctional deaminase-reductase domain-containing protein; COG0262 Dihydrofolate reductase. (168 aa)
AHM58288.1Ribose-phosphate pyrophosphokinase; COG0462 Phosphoribosylpyrophosphate synthetase. (308 aa)
AHM58291.1Protoporphyrinogen oxidase; COG4635 Flavodoxin. (174 aa)
AHM58294.1COG0046 Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain. (87 aa)
AHM58314.1Class I and II aminotransferase; COG0156 7-keto-8-aminopelargonate synthetase and related enzymes. (419 aa)
dinBDNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. (365 aa)
AHM58331.1Hypothetical protein. (745 aa)
AHM58335.1COG1428 Deoxynucleoside kinases. (220 aa)
AHM58336.1Hypothetical protein; COG1678 Putative transcriptional regulator; Belongs to the UPF0301 (AlgH) family. (193 aa)
AHM58378.1COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog. (148 aa)
AHM58383.1ECF subfamily RNA polymerase sigma-24 factor; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily. (190 aa)
AHM58439.1COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ). (345 aa)
AHM58462.1Beta-lactamase; COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I. (260 aa)
AHM58477.1Inosine 5-monophosphate dehydrogenase; COG0516 IMP dehydrogenase/GMP reductase. (497 aa)
AHM58529.1RpoD subfamily RNA polymerase sigma-70 subunit; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (287 aa)
AHM58566.1RNA polymerase, sigma 70 subunit, rpod subfamily protein; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (287 aa)
pdxHPyridoxamine-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). (214 aa)
accAacetyl-CoA carboxylase carboxyltransferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (315 aa)
queA-2S-adenosylmethionine--tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). (416 aa)
AHM58667.1COG0656 Aldo/keto reductases, related to diketogulonate reductase. (315 aa)
purUFormyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (279 aa)
purLPhosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. (1229 aa)
AHM58777.1RNA polymerase, sigma-24 subunit, ecf subfamily protein; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily. (185 aa)
AHM58826.1Amine oxidase; COG1233 Phytoene dehydrogenase and related proteins. (412 aa)
AHM58835.1COG0285 Folylpolyglutamate synthase; Belongs to the folylpolyglutamate synthase family. (426 aa)
AHM58837.1Hypothetical protein; COG0135 Phosphoribosylanthranilate isomerase. (210 aa)
AHM58893.1Hypothetical protein; COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain). (210 aa)
AHM58910.1COG1466 DNA polymerase III, delta subunit. (355 aa)
AHM58938.1Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. (366 aa)
AHM58941.1COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily. (187 aa)
AHM58974.1COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily. (182 aa)
mobABifunctional molybdopterin-guanine dinucleotide biosynthesis protein MobB/MobA; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor. (393 aa)
AHM58987.1COG0315 Molybdenum cofactor biosynthesis enzyme. (158 aa)
AHM58988.1Molybdenum cofactor synthesis domain protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. (401 aa)
AHM58989.1Primary replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. (508 aa)
AHM58998.1Von willebrand factor type a; COG2304 Uncharacterized protein containing a von Willebrand factor type A (vWA) domain. (476 aa)
AHM59013.1Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (325 aa)
AHM59025.1COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I. (253 aa)
nadEGlutamine-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (628 aa)
AHM59057.1COG0535 Predicted Fe-S oxidoreductases. (409 aa)
AHM59142.1COG0500 SAM-dependent methyltransferases. (258 aa)
AHM59158.1COG0720 6-pyruvoyl-tetrahydropterin synthase. (135 aa)
folECOG0302 GTP cyclohydrolase I. (222 aa)
AHM59168.1RNA polymerase, sigma-24 subunit, ecf subfamily protein; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily. (179 aa)
AHM59173.1Riboflavin kinase/FMN adenylyltransferase; COG0196 FAD synthase; Belongs to the ribF family. (310 aa)
AHM59276.1RNA-directed DNA polymerase; COG3344 Retron-type reverse transcriptase. (192 aa)
AHM59277.1RNA-directed DNA polymerase; COG3344 Retron-type reverse transcriptase. (199 aa)
AHM59348.1RepB; COG5527 Protein involved in initiation of plasmid replication. (353 aa)
AHM59364.1COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog. (185 aa)
AHM59413.1D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein; COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (317 aa)
AHM59417.14-hydroxythreonine-4-phosphate dehydrogenase; COG1995 Pyridoxal phosphate biosynthesis protein; Belongs to the PdxA family. (337 aa)
murAUDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (438 aa)
AHM59481.1DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] (374 aa)
AHM59531.1Mg-chelatase subunit ChlD; COG2304 Uncharacterized protein containing a von Willebrand factor type A (vWA) domain. (350 aa)
coaDPhosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (155 aa)
pyrEOrotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (216 aa)
kdsB3-deoxy-manno-octulosonate cytidylyltransferase (CMP-KDO synthetase); Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. (252 aa)
hemLCOG0001 Glutamate-1-semialdehyde aminotransferase. (434 aa)
guaAGMP synthase; Catalyzes the synthesis of GMP from XMP. (509 aa)
AHM59578.1Dihydrofolate reductase region; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. (165 aa)
AHM59582.1Competence/damage-inducible protein CinA; COG1058 Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA; Belongs to the CinA family. (417 aa)
AHM59585.1COG0161 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (440 aa)
bioDDethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. (201 aa)
bioBBiotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (364 aa)
AHM59591.12-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase. (160 aa)
thyAThymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. (264 aa)
AHM59612.1COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily. (174 aa)
AHM59652.1COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases. (559 aa)
AHM59653.1Hypothetical protein. (134 aa)
AHM59714.1Acyltransferase; COG0454 Histone acetyltransferase HPA2 and related acetyltransferases. (143 aa)
trpATryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (265 aa)
trpBTryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (400 aa)
trpFCOG0135 Phosphoribosylanthranilate isomerase; Belongs to the TrpF family. (219 aa)
AHM59760.1COG0134 Indole-3-glycerol phosphate synthase. (281 aa)
trpDAnthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (337 aa)
pyrGCTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (541 aa)
cmkCOG0283 Cytidylate kinase. (233 aa)
AHM59819.1COG0284 Orotidine-5'-phosphate decarboxylase. (276 aa)
pyrDDihydroorotate dehydrogenase 2; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (373 aa)
AHM59865.1Hypothetical protein; COG0500 SAM-dependent methyltransferases. (271 aa)
purDCOG0151 Phosphoribosylamine-glycine ligase; Belongs to the GARS family. (427 aa)
hemAglutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (425 aa)
purCCOG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; Belongs to the SAICAR synthetase family. (316 aa)
AHM59948.1Hypothetical protein; Involved in the import of queuosine (Q) precursors, required for Q precursor salvage; Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily. (263 aa)
AHM59970.1COG0408 Coproporphyrinogen III oxidase. (302 aa)
AHM59973.1COG0307 Riboflavin synthase alpha chain. (198 aa)
AHM60024.1COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily. (185 aa)
AHM60106.1COG3530 Uncharacterized protein conserved in bacteria. (71 aa)
AHM60112.1Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase, long form; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (561 aa)
AHM60163.1Hypothetical protein. (204 aa)
carACOG0505 Carbamoylphosphate synthase small subunit; Belongs to the CarA family. (355 aa)
rpoADNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (329 aa)
rpoCDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1440 aa)
rpoBDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1288 aa)
nusGTranscription antitermination protein nusg; Participates in transcription elongation, termination and antitermination. (184 aa)
pyrHUridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (236 aa)
nadDNicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (190 aa)
AHM60217.1COG0194 Guanylate kinase. (200 aa)
AHM60219.1COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily. (245 aa)
AHM60235.1WbqC-like family protein. (213 aa)
AHM60267.1COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily. (197 aa)
AHM60269.1Hypothetical protein. (351 aa)
AHM60270.1Phage/plasmid primase, P4 family protein; COG3378 Predicted ATPase. (507 aa)
AHM60290.1COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily. (196 aa)
AHM60378.1COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily. (164 aa)
AHM60402.1PfkB domain-containing protein; COG2870 ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase. (331 aa)
hemEUroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. (347 aa)
uppCOG0035 Uracil phosphoribosyltransferase. (231 aa)
AHM60419.1COG0634 Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (175 aa)
adkAdenylate kinase-like kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (192 aa)
AHM60454.1COG0355 F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit). (83 aa)
atpDATP synthase F1 subcomplex subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. (501 aa)
AHM60458.1COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily. (234 aa)
AHM60465.1rfaE bifunctional protein; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. (163 aa)
AHM60489.1COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily. (170 aa)
AHM60503.1ATP:cob(I)alamin adenosyltransferase; Belongs to the Cob(I)alamin adenosyltransferase family. (185 aa)
AHM60516.1COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog. (486 aa)
AHM60537.1Family 3 adenylate cyclase; COG0784 FOG: CheY-like receiver; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (386 aa)
AHM60611.1Radical SAM protein; COG0535 Predicted Fe-S oxidoreductases. (364 aa)
accDacetyl-CoA carboxylase, carboxyl transferase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA. (279 aa)
AHM60642.1Hypothetical protein; COG3839 ABC-type sugar transport systems, ATPase components. (101 aa)
rhoTranscription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. (699 aa)
AHM60651.1COG4992 Ornithine/acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (425 aa)
AHM60721.1COG0044 Dihydroorotase and related cyclic amidohydrolases. (447 aa)
coaEdephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (218 aa)
AHM60734.1Nusb antitermination factor; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. (381 aa)
AHM60772.1ECF subfamily RNA polymerase sigma-70 factor; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily. (191 aa)
AHM60805.1COG3193 Uncharacterized protein, possibly involved in utilization of glycolate and propanediol. (132 aa)
kynUKynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. (433 aa)
kmoKynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid; Belongs to the aromatic-ring hydroxylase family. KMO subfamily. (456 aa)
AHM60934.1dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. (164 aa)
AHM60995.1RNA polymerase, sigma-24 subunit, ECF subfamily protein; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. (192 aa)
AHM61004.1COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily. (176 aa)
AHM61008.1COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily. (188 aa)
coaXPantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. (243 aa)
purKPhosphoribosylaminoimidazole carboxylase, ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (378 aa)
purEPhosphoribosylaminoimidazole carboxylase catalytic subunit PurE; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (178 aa)
atpGATP synthase subunit gamma; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (302 aa)
atpAProton translocating ATP synthase, F1 subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. (526 aa)
atpHATP synthase f1, delta subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (186 aa)
atpFATP synthase F0 subcomplex subunit B; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family. (164 aa)
atpEATP synthase subunit c; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (91 aa)
atpBATP synthase F0 subunit A; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. Belongs to the ATPase A chain family. (361 aa)
AHM61048.1COG1587 Uroporphyrinogen-III synthase. (259 aa)
guaBInosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (490 aa)
AHM61072.1COG3172 Predicted ATPase/kinase involved in NAD metabolism. (171 aa)
AHM61075.1Hypothetical protein. (211 aa)
AHM61082.1Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (337 aa)
polADNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. (960 aa)
AHM61286.1Iron-sulfur cluster binding protein; COG1600 Uncharacterized Fe-S protein. (260 aa)
nusATranscription elongation factor NusA; Participates in both transcription termination and antitermination. (413 aa)
AHM61329.1COG2104 Sulfur transfer protein involved in thiamine biosynthesis. (67 aa)
AHM63638.1Cytochrome oxidase assembly; COG1612 Uncharacterized protein required for cytochrome oxidase assembly. (359 aa)
thiCPhosphomethylpyrimidine synthase ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. (622 aa)
AHM61331.1COG0352 Thiamine monophosphate synthase. (204 aa)
AHM61332.1COG0351 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase. (246 aa)
thiEThiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. (217 aa)
thiGThiazole biosynthesis family protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. (253 aa)
AHM61335.1COG1060 Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes. (369 aa)
AHM61336.1RNA polymerase, sigma-24 subunit, ECF subfamily protein; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. (282 aa)
AHM61375.1Ribonucleoside-diphosphate reductase subunit alpha; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (799 aa)
AHM61376.1COG0208 Ribonucleotide reductase, beta subunit. (330 aa)
AHM61389.1Hypothetical protein; COG3298 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB. (243 aa)
AHM61421.1RNA polymerase, sigma-24 subunit, ECF subfamily protein; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily. (204 aa)
AHM61454.1Phosphoribosylformylglycinamidine cyclo-ligase; COG0150 Phosphoribosylaminoimidazole (AIR) synthetase. (387 aa)
AHM61518.1ECF subfamily RNA polymerase sigma-70 factor; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily. (199 aa)
AHM61585.1Radical SAM domain protein; COG0535 Predicted Fe-S oxidoreductases. (274 aa)
AHM63549.1COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily. (183 aa)
fclGDP-L-fucose synthase; Catalyzes the two-step NADP-dependent conversion of GDP-4- dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction. (314 aa)
tdkCOG1435 Thymidine kinase. (199 aa)
AHM61642.1Hypothetical protein; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. (375 aa)
AHM61657.1COG0157 Nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family. (294 aa)
AHM61666.1COG0113 Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. (329 aa)
AHM61667.1Ankyrin repeat-containing protein. (416 aa)
AHM61675.1COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily. (169 aa)
AHM61682.1Hypothetical protein; COG4119 Predicted NTP pyrophosphohydrolase. (150 aa)
AHM61719.1COG2154 Pterin-4a-carbinolamine dehydratase. (77 aa)
AHM61724.1Nucleotide sugar dehydrogenase; COG1004 Predicted UDP-glucose 6-dehydrogenase. (444 aa)
AHM61732.1Hypothetical protein. (65 aa)
pdxJPyridoxine 5'-phosphate synthase; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate. (239 aa)
ppnKInorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (291 aa)
purHBifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful). (508 aa)
purNPhosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (199 aa)
AHM61769.1COG0110 Acetyltransferase (isoleucine patch superfamily). (156 aa)
ribH6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. (163 aa)
pdhAPyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (346 aa)
hemHFerrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (346 aa)
AHM61821.1Spheroidene monooxygenase; COG0480 Translation elongation factors (GTPases). (230 aa)
AHM61830.1dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. (304 aa)
hemCPorphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. (310 aa)
AHM61836.1COG2812 DNA polymerase III, gamma/tau subunits. (403 aa)
AHM61837.1UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon). (402 aa)
comB2-phosphosulfolactate phosphatase; COG2045 Phosphosulfolactate phosphohydrolase and related enzymes; Belongs to the ComB family. (241 aa)
AHM61889.1Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (121 aa)
dxs1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (644 aa)
ndkNucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (140 aa)
AHM61927.1COG0572 Uridine kinase; Belongs to the uridine kinase family. (205 aa)
AHM61947.1COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily. (188 aa)
AHM61957.1COG0212 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. (193 aa)
lipALipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (292 aa)
AHM61994.1COG1239 Mg-chelatase subunit ChlI. (515 aa)
queAS-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). (348 aa)
AHM62043.1DNA polymerase III subunits gamma and tau. (158 aa)
dnaXDNA polymerase III subunits tau/gamma; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (388 aa)
AHM62055.1uroporphyrin-III C-methyltransferase; COG0007 Uroporphyrinogen-III methylase. (249 aa)
AHM62058.1Molybdenum cofactor synthesis protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. (411 aa)
AHM62064.1GTP cyclohydrolase subunit MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (315 aa)
AHM62065.1Hypothetical protein; COG1977 Molybdopterin converting factor, small subunit. (77 aa)
AHM62066.1COG0314 Molybdopterin converting factor, large subunit. (159 aa)
AHM62068.1Molybdenum cofactor guanylyltransferase; COG0746 Molybdopterin-guanine dinucleotide biosynthesis protein A. (176 aa)
AHM62090.1COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily. (179 aa)
AHM62097.1Ribose-phosphate pyrophosphokinase; COG0462 Phosphoribosylpyrophosphate synthetase. (313 aa)
AHM62104.1COG1981 Predicted membrane protein. (203 aa)
AHM62139.1Radical SAM superfamily protein; COG0535 Predicted Fe-S oxidoreductases. (353 aa)
AHM62155.1PHP family phosphohydrolase, histidinol phosphatase; COG1796 DNA polymerase IV (family X). (571 aa)
pyrBCOG0540 Aspartate carbamoyltransferase, catalytic chain; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (308 aa)
AHM62175.1Glyoxalase/bleomycin resistance protein/dioxygenase; COG2764 Uncharacterized protein conserved in bacteria. (136 aa)
AHM62190.1Amidophosphoribosyltransferase; COG0034 Glutamine phosphoribosylpyrophosphate amidotransferase. (629 aa)
thiLThiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. (347 aa)
fcl-2GDP-L-fucose synthase; Catalyzes the two-step NADP-dependent conversion of GDP-4- dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction. (283 aa)
AHM62209.1NGN domain-containing protein; COG0250 Transcription antiterminator. (177 aa)
AHM62353.1COG0259 Pyridoxamine-phosphate oxidase. (155 aa)
AHM62389.1Cobalamin synthesis protein P47K; COG0523 Putative GTPases (G3E family). (326 aa)
proCPyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (268 aa)
AHM62425.1COG0635 Coproporphyrinogen III oxidase and related Fe-S oxidoreductases; Belongs to the anaerobic coproporphyrinogen-III oxidase family. (452 aa)
folD5,10-methylenetetrahydrofolate dehydrogenase (nadp+); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (300 aa)
queERadical SAM domain-containing protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. (214 aa)
AHM62450.1COG0720 6-pyruvoyl-tetrahydropterin synthase. (140 aa)
purAAdenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (429 aa)
AHM62492.1COG0720 6-pyruvoyl-tetrahydropterin synthase. (178 aa)
AHM62494.1Ribonucleoside-diphosphate reductase; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. (1099 aa)
AHM62498.1Quinolinate synthetase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (346 aa)
AHM62499.1L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate. (522 aa)
ctaBProtoheme ix farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group. (298 aa)
AHM62510.1COG1648 Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain). (202 aa)
AHM62542.1Hypothetical protein. (666 aa)
AHM62543.1Dihydroorotase, multifunctional complex type; COG0044 Dihydroorotase and related cyclic amidohydrolases. (427 aa)
AHM62551.1COG0015 Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (450 aa)
AHM62572.1Hypothetical protein; COG2902 NAD-specific glutamate dehydrogenase. (2423 aa)
dutDeoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. (148 aa)
dacAHypothetical protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. (303 aa)
AHM62595.1COG0294 Dihydropteroate synthase and related enzymes. (259 aa)
AHM62608.1Von willebrand factor type a; COG2304 Uncharacterized protein containing a von Willebrand factor type A (vWA) domain. (322 aa)
AHM62685.1Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. (638 aa)
AHM62696.1Cytochrome oxidase assembly; COG1612 Uncharacterized protein required for cytochrome oxidase assembly. (356 aa)
AHM62763.1Glyoxalase/bleomycin resistance protein/dioxygenase; COG2764 Uncharacterized protein conserved in bacteria. (157 aa)
AHM62767.1Von Willebrand factor type A-like protein. (397 aa)
AHM62805.1Hypothetical protein. (207 aa)
AHM62894.1Transposase; COG2764 Uncharacterized protein conserved in bacteria. (133 aa)
AHM62900.1COG3344 Retron-type reverse transcriptase. (501 aa)
AHM62962.1NIPSNAP family containing protein. (269 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (398 aa)
AHM62975.1Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. (696 aa)
AHM62984.1RNA polymerase, sigma-24 subunit, ECF subfamily protein; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily. (259 aa)
AHM63009.1Acetylornithine transaminase; COG0160 4-aminobutyrate aminotransferase and related aminotransferases; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (452 aa)
AHM63012.1COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily. (183 aa)
AHM63090.1RNA polymerase, sigma-24 subunit, ecf subfamily protein; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily. (190 aa)
AHM63234.1Haloacid dehalogenase-like hydrolase; COG1011 Predicted hydrolase (HAD superfamily). (215 aa)
priAPrimosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (840 aa)
ribBAGTP cyclohydrolase II/3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. (408 aa)
dnaGDNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (638 aa)
apaGCO2+/MG2+ efflux protein ApaG; COG2967 Uncharacterized protein affecting Mg2+/Co2+ transport. (128 aa)
AHM63333.1Hypothetical protein; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. (108 aa)
AHM63334.1Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (408 aa)
pncBNicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. (394 aa)
tgttRNA-guanine transglycosylase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the [...] (376 aa)
AHM63372.1RNA polymerase, sigma-24 subunit, ecf subfamily protein; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily. (204 aa)
AHM63410.1COG2176 DNA polymerase III, alpha subunit (gram-positive type). (1413 aa)
Your Current Organism:
Flammeovirgaceae bacterium 311
NCBI taxonomy Id: 1257021
Other names: F. bacterium 311
Server load: low (12%) [HD]