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ACA1_145560 ACA1_145560 ACA1_191150 ACA1_191150 ACA1_261440 ACA1_261440 ACA1_274150 ACA1_274150 ACA1_353580 ACA1_353580 ACA1_091330 ACA1_091330 ACA1_093760 ACA1_093760 ACA1_241720 ACA1_241720 ACA1_038550 ACA1_038550 ACA1_366600 ACA1_366600 ACA1_271340 ACA1_271340 ACA1_191560 ACA1_191560 ACA1_131000 ACA1_131000 ACA1_106370 ACA1_106370 ACA1_066870 ACA1_066870 ACA1_130560 ACA1_130560 ACA1_309320 ACA1_309320 ACA1_177470 ACA1_177470 ACA1_177380 ACA1_177380 ACA1_042250 ACA1_042250 ACA1_383710 ACA1_383710 ACA1_061870 ACA1_061870 ACA1_368710 ACA1_368710 ACA1_369570 ACA1_369570 ACA1_155810 ACA1_155810 ACA1_200220 ACA1_200220 ACA1_201580 ACA1_201580 ACA1_263160 ACA1_263160 ACA1_054360 ACA1_054360 ACA1_053240 ACA1_053240 ACA1_280600 ACA1_280600 ACA1_385410 ACA1_385410 ACA1_325590 ACA1_325590 ACA1_158530 ACA1_158530 ACA1_360340 ACA1_360340 ACA1_149380 ACA1_149380 ACA1_398190 ACA1_398190 ACA1_360260 ACA1_360260 ACA1_175190 ACA1_175190 ACA1_295600 ACA1_295600 ACA1_175510 ACA1_175510 ACA1_287820 ACA1_287820 ACA1_288720 ACA1_288720 ACA1_291490 ACA1_291490
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ACA1_145560UBA/TS-N domain containing protein. (616 aa)
ACA1_191150Triosephosphate isomerase. (211 aa)
ACA1_261440Poly [ADP-ribose] polymerase. (742 aa)
ACA1_2741506PF2K domain-containing protein. (309 aa)
ACA1_353580ROK family protein, putative. (316 aa)
ACA1_091330Pyruvate kinase; Belongs to the pyruvate kinase family. (524 aa)
ACA1_093760ADPdependent glucokinase. (493 aa)
ACA1_241720ROK family protein. (314 aa)
ACA1_038550Phosphoglucomutase, putative. (1302 aa)
ACA1_366600Xylulose kinase. (558 aa)
ACA1_271340Phosphoribosylpyrophosphate synthetase. (307 aa)
ACA1_1915606-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (480 aa)
ACA1_131000Hydrolase, NUDIX family. (192 aa)
ACA1_106370Glyoxylate reductase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (368 aa)
ACA1_066870Glucose-6-phosphate isomerase; Belongs to the GPI family. (561 aa)
ACA1_130560Glucosyl hydrolase family protein; Belongs to the glycosyl hydrolase 43 family. (347 aa)
ACA1_309320Glucose-6-phosphate 1-epimerase; Belongs to the glucose-6-phosphate 1-epimerase family. (297 aa)
ACA1_177470ADP-sugar pyrophosphatase, putative; Belongs to the Nudix hydrolase family. (211 aa)
ACA1_177380Glucokinase. (352 aa)
ACA1_042250Phosphoglucomutase, putative; Belongs to the phosphohexose mutase family. (571 aa)
ACA1_383710Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. (532 aa)
ACA1_061870Gluconokinase; Belongs to the gluconokinase GntK/GntV family. (172 aa)
ACA1_368710Pyrophosphate--fructose 6-phosphate 1-phosphotransferase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (572 aa)
ACA1_369570Tetratricopeptide repeat domain containing protein. (359 aa)
ACA1_155810Fructose6-phosphate-2-kinase, putative. (580 aa)
ACA1_200220Fructose-1,6-bisphosphatase, putative; Belongs to the FBPase class 1 family. (342 aa)
ACA1_2015806-phosphofructokinase family protein. (362 aa)
ACA1_263160Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. (321 aa)
ACA1_054360Mannose-6-phosphate isomerase; Belongs to the mannose-6-phosphate isomerase type 1 family. (457 aa)
ACA1_053240Phosphoglycerate kinase. (417 aa)
ACA1_280600Phosphoribosylpyrophosphate synthetase. (309 aa)
ACA1_385410Transketolase, putative. (851 aa)
ACA1_325590Phosphoglycerate mutase family domain containing protein. (327 aa)
ACA1_158530Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. (499 aa)
ACA1_360340Urb2 domain-containing protein. (1921 aa)
ACA1_149380Ribose 5phosphate isomerase A, putative. (258 aa)
ACA1_3981906-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (500 aa)
ACA1_360260SMP30/CGR1 family protein. (298 aa)
ACA1_1751906phosphofructokinase. (888 aa)
ACA1_2956006-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (199 aa)
ACA1_175510Xylose isomerase. (437 aa)
ACA1_287820Transketolase. (705 aa)
ACA1_288720Aldose 1epimerase subfamily protein. (328 aa)
ACA1_291490Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (225 aa)
Your Current Organism:
Acanthamoeba castellanii
NCBI taxonomy Id: 1257118
Other names: A. castellanii str. Neff, Acanthamoeba castellanii Neff strain, Acanthamoeba castellanii str. Neff, Acanthamoeba castellanii strain Neff
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